(Q33724465)

28 July 2017

title

Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting (English)

1 reference

28 July 2017

1 reference

Flávio S J de Souza

1

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28 July 2017

Andrea M Santangelo

2

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28 July 2017

Viviana Bumaschny

3

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28 July 2017

María Elena Avale

4

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28 July 2017

James L Smart

5

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28 July 2017

Malcolm J Low

6

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28 July 2017

Marcelo Rubinstein

7

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28 July 2017

language of work or name

English

0 references

publication date

1 April 2005

1 reference

Molecular and Cellular Biology

28 July 2017

published in

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28 July 2017

volume

25

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28 July 2017

issue

8

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28 July 2017

page(s)

3076-3086

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rVISTA 2.0: evolutionary analysis of transcription factor binding sites

28 July 2017

cites work

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Proopiomelanocortin and energy balance: insights from human and murine genetics

21 June 2018

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21 June 2018

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Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36).

21 June 2018

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21 June 2018

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The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1.

21 June 2018

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21 June 2018

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21 June 2018

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Proopiomelanocortin, a polypeptide precursor with multiple functions: from physiology to pathological conditions

21 June 2018

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Proopiomelanocortin gene expression and DNA methylation: implications for Cushing's syndrome and beyond

21 June 2018

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Tpit determines alternate fates during pituitary cell differentiation

21 June 2018

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STAT3 signalling is required for leptin regulation of energy balance but not reproduction

21 June 2018

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21 June 2018

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21 June 2018

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Gut hormone PYY(3-36) physiologically inhibits food intake

21 June 2018

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Pituitary development: regulatory codes in mammalian organogenesis

21 June 2018

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Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors

21 June 2018

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Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals

21 June 2018

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Vertebrate genome sequencing: building a backbone for comparative genomics

21 June 2018

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Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

21 June 2018

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A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins

21 June 2018

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Obesity and the regulation of energy balance

21 June 2018

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21 June 2018

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Central nervous system control of food intake

21 June 2018

1 reference

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Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

21 June 2018

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Discovery and modeling of transcriptional regulatory regions

21 June 2018

1 reference

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Sequence and distribution of pro-opiomelanocortin in the pituitary and the brain of the chicken (Gallus gallus).

21 June 2018

1 reference

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Analysis of vertebrate SCL loci identifies conserved enhancers

21 June 2018

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The Pit-1 homeodomain and beta-domain interact with Ets-1 and modulate synergistic activation of the rat prolactin promoter

21 June 2018

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The quantitative trait locus on chromosome 2 for serum leptin levels is confirmed in African-Americans

21 June 2018

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Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

21 June 2018

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The pan-pituitary activator of transcription, Ptx1 (pituitary homeobox 1), acts in synergy with SF-1 and Pit1 and is an upstream regulator of the Lim-homeodomain gene Lim3/Lhx3.

21 June 2018

1 reference

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NeuroD1/beta2 contributes to cell-specific transcription of the proopiomelanocortin gene

21 June 2018

1 reference

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Antagonism between Nur77 and glucocorticoid receptor for control of transcription.

21 June 2018

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A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

A dot-matrix program with dynamic threshold control suited for genomic DNA and protein sequence analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

DNA elements with AT-rich core sequences direct pituitary cell-specific expression of the pro-opiomelanocortin gene in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

A PCR-based method for high stringency screening of DNA libraries

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Rat and mouse proopiomelanocortin gene sequences target tissue-specific expression to the pituitary gland but not to the hypothalamus of transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

The POU homeodomain transcription factor Oct-1 is essential for activity of the gonadotropin-releasing hormone neuron-specific enhancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

A transgenic marker for newly born granule cells in dentate gyrus.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

The central melanocortin system regulates food intake in goldfish.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Transgenic mice engineered to target Cre/loxP-mediated DNA recombination into catecholaminergic neurons

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Role of Signal Transducer and Activator of Transcription 3 in Regulation of Hypothalamic Proopiomelanocortin Gene Expression by Leptin

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Functional analysis of chicken Sox2 enhancers highlights an array of diverse regulatory elements that are conserved in mammals.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Pituitary corticotroph ontogeny and regulation in transgenic zebrafish

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Activation of central melanocortin pathways by fenfluramine

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Brn-4 transcription factor expression targeted to the early developing mouse pancreas induces ectopic glucagon gene expression in insulin-producing beta cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Comparative genomics of the SOX9 region in human and Fugu rubripes: conservation of short regulatory sequence elements within large intergenic regions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Linkage and association studies between the proopiomelanocortin (POMC) gene and obesity in caucasian families

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Immunohistochemical localization and biochemical characterization of two novel decapeptides derived from POMC-A in the trout hypothalamus.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Authentic cell-specific and developmentally regulated expression of pro-opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069613

A role for estrogen-related receptor alpha in the control of mitochondrial fatty acid beta-oxidation during brown adipocyte differentiation

30 October 2018

1 reference

12 December 2020

A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10

1 reference

12 December 2020

Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin

1 reference

12 December 2020

Normal variation in leptin levels in associated with polymorphisms in the proopiomelanocortin gene, POMC

1 reference

12 December 2020

10.1128/MCB.25.8.3076-3086.2005

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference