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Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
title
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
(English)
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
main subject
obesity
0 references
Signal transducer and activator of transcription 3
1 reference
stated in
GOA release 2020-03-11
author
Katsutaro Morino
object named as
Katsutaro Morino
series ordinal
4
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Gerald I. Shulman
series ordinal
6
object named as
Gerald I. Shulman
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
Susanne Neschen
series ordinal
3
object named as
Susanne Neschen
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
author name string
Qian Gao
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
Michael J. Wolfgang
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
Tamas L. Horvath
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
Xin-Yuan Fu
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
language of work or name
English
0 references
publication date
30 March 2004
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stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
published in
Proceedings of the National Academy of Sciences of the United States of America
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stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
volume
101
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
issue
13
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stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
page(s)
4661–4666
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stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
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Targeted disruption of the melanocortin-4 receptor results in obesity in mice
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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
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Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
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Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
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Congenital leptin deficiency is associated with severe early-onset obesity in humans
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7 April 2017
Endothelial cells require STAT3 for protection against endotoxin-induced inflammation
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PubMed Central
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STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity
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Leukemia inhibitory factor inhibits neuronal terminal differentiation through STAT3 activation
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Direct regulation of pituitary proopiomelanocortin by STAT3 provides a novel mechanism for immuno-neuroendocrine interfacing
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Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei.
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29 September 2017
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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29 September 2017
STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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29 September 2017
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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29 September 2017
Defective STAT signaling by the leptin receptor in diabetic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
retrieved
29 September 2017
Reflections on STAT3, STAT5, and STAT6 as fat STATs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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29 September 2017
The interleukin-6-activated acute-phase response factor is antigenically and functionally related to members of the signal transducer and activator of transcription (STAT) family
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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29 September 2017
Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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29 September 2017
Role of brain insulin receptor in control of body weight and reproduction
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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3 June 2018
Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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27 November 2018
Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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27 November 2018
Interleukin-6-deficient mice develop mature-onset obesity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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27 November 2018
DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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27 November 2018
Role of STAT3 and PI 3-kinase/Akt in mediating the survival actions of cytokines on sensory neurons
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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27 November 2018
Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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27 November 2018
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
retrieved
27 November 2018
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
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27 November 2018
Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
retrieved
27 November 2018
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384803
retrieved
27 November 2018
Specific ablation of Stat3beta distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15070774
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Leptin activates neurons in ventrobasal hypothalamus and brainstem
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15070774
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15070774
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.0303992101
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
ADS bibcode
2004PNAS..101.4661G
0 references
PMCID
384803
0 references
PubMed ID
15070774
1 reference
stated in
PubMed
PubMed ID
15070774
retrieved
31 January 2017
ResearchGate publication ID
8630546
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