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Towards a molecular understanding of adaptive thermogenesis
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scholarly article
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Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
review article
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Europe PubMed Central
title
Towards a molecular understanding of adaptive thermogenesis
(English)
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Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
main subject
thermogenesis
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author name string
B B Lowell
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1
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Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
B M Spiegelman
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2
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Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
language of work or name
English
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publication date
1 April 2000
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Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
published in
Nature
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Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
volume
404
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Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
page(s)
652-660
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Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
issue
6778
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Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
exact match
https://scigraph.springernature.com/pub.10.1038/35007527
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Cold acclimation and the electromyogram of unanesthetized rats
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Regulation of shivering and non-shivering heat production during acclimation of rats
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Influence of mild cold on 24 h energy expenditure, resting metabolism and diet-induced thermogenesis.
1 reference
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reference URL
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Changes in energy expenditure resulting from altered body weight.
1 reference
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Crossref
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7 January 2021
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Expenditure and storage of energy in man.
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7 January 2021
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Regulatory alterations of daily energy expenditure induced by fasting or overfeeding in unrestrained rats.
1 reference
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7 January 2021
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Role of nonexercise activity thermogenesis in resistance to fat gain in humans.
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The response to long-term overfeeding in identical twins
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Consumption of a low protein diet increases norepinephrine turnover in brown adipose tissue of adult rats
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Effect of environmental temperature on energy balance and thermogenesis in rats fed normal or low protein diets
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Sympathoadrenal system and regulation of thermogenesis
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7 January 2021
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Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline
1 reference
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7 January 2021
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From lesions to leptin: hypothalamic control of food intake and body weight.
1 reference
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Crossref
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Brown adipose tissue thermogenesis and obesity
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The significance and mechanism of mitochondrial proton conductance
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Thyroid hormone control of thermogenesis and energy balance
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Contribution of mitochondrial proton leak to skeletal muscle respiration and to standard metabolic rate
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Role of leptin in the neuroendocrine response to fasting
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Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus.
1 reference
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Cellular energy utilization and molecular origin of standard metabolic rate in mammals
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Regulation of energy transduction and electron transfer in cytochrome c oxidase by adenine nucleotides.
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Abnormal brown and white fat development in transgenic mice overexpressing glycerol 3-phosphate dehydrogenase
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Thermogenic mechanisms in brown fat
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7 January 2021
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inferred from DOI database lookup
Structure and function of the uncoupling protein from brown adipose tissue
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7 January 2021
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inferred from DOI database lookup
Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese
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7 January 2021
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Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia
1 reference
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Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression
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7 January 2021
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UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue
1 reference
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7 January 2021
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Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
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Recombinant human uncoupling protein-3 increases thermogenesis in yeast cells
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7 January 2021
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Assessment of uncoupling activity of uncoupling protein 3 using a yeast heterologous expression system
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Transport function and regulation of mitochondrial uncoupling proteins 2 and 3
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BMCP1, a novel mitochondrial carrier with high expression in the central nervous system of humans and rodents, and respiration uncoupling activity in recombinant yeast
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UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells
1 reference
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7 January 2021
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Tissue-dependent upregulation of rat uncoupling protein-2 expression in response to fasting or cold.
1 reference
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7 January 2021
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Elevated free fatty acids induce uncoupling protein 3 expression in muscle: a potential explanation for the effect of fasting.
1 reference
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Oxidative Metabolism in Cells Isolated from Brown Adipose Tissue. 2. Catecholamine Regulated Respiratory Control
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Fatty acid cycling mechanism and mitochondrial uncoupling proteins.
1 reference
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Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs
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7 January 2021
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Function and regulation of the beta 3-adrenoceptor
1 reference
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7 January 2021
based on heuristic
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Targeted disruption of the beta 3-adrenergic receptor gene.
1 reference
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Crossref
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7 January 2021
based on heuristic
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Beta 3-adrenergic receptor stimulation restores message and expression of brown-fat mitochondrial uncoupling protein in adult dogs
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35007527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of leptin in fat regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35007527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor-mediated regional sympathetic nerve activation by leptin.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35007527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Satiety effect and sympathetic activation of leptin are mediated by hypothalamic melanocortin system.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic central leptin infusion enhances insulin-stimulated glucose metabolism and favors the expression of uncoupling proteins.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35007527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of fasting and refeeding on the level of uncoupling protein mRNA in rat brown adipose tissue: evidence for diet-induced and cold-induced responses.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
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Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
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7 January 2021
based on heuristic
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Reduced rate of energy expenditure as a risk factor for body-weight gain.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Energy expenditure and intake in infants born to lean and overweight mothers
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
inferred from DOI database lookup
Skeletal muscle metabolism is a major determinant of resting energy expenditure
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7 January 2021
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Nuclear respiratory factors 1 and 2 utilize similar glutamine-containing clusters of hydrophobic residues to activate transcription
1 reference
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Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis
1 reference
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7 January 2021
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1 reference
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7 January 2021
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Mitochondrial genes as sites of primary action of steroid hormones
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inferred from DOI database lookup
An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene
1 reference
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7 January 2021
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inferred from DOI database lookup
Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A
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Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor gamma
1 reference
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based on heuristic
inferred from DOI database lookup
Induction of uncoupling protein in brown adipose tissue. Synergy between norepinephrine and pioglitazone, an insulin-sensitizing agent
1 reference
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
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Activation of the nuclear receptor peroxisome proliferator-activated receptor gamma promotes brown adipocyte differentiation
1 reference
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
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Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
inferred from DOI database lookup
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
1 reference
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the beta(3)-adrenergic receptor and/or a putative beta(4)-adrenergic receptor on the expression of uncoupling proteins and peroxisome proliferator-activated receptor-gamma coactivator-1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35007527
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
inferred from DOI database lookup
Physiological approach to maturation of brown adipocytes in primary cell culture.
1 reference
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
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Characterization of the 5'-flanking and 5'-untranslated regions of the cyclic adenosine 3',5'-monophosphate-responsive human type 2 iodothyronine deiodinase gene
1 reference
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7 January 2021
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inferred from DOI database lookup
Body mass dependence of H+ leak in mitochondria and its relevance to metabolic rate
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
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inferred from DOI database lookup
Keilin's Respiratory Chain Concept and Its Chemiosmotic Consequences
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7 January 2021
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inferred from DOI database lookup
Regulation of oxidative phosphorylation in the mammalian cell
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7 January 2021
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The metabolic implications of intracellular circulation
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of calcium ions in regulation of mammalian intramitochondrial metabolism
1 reference
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
inferred from DOI database lookup
Control of respiration and ATP synthesis in mammalian mitochondria and cells
1 reference
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https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
inferred from DOI database lookup
Thermogenesis in muscle
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35007527
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7 January 2021
based on heuristic
inferred from DOI database lookup
Malignant hyperthermia
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of sarcoplasmic reticulum Ca2+ transport proteins in cold-acclimating ducklings
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35007527
retrieved
7 January 2021
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Identifiers
DOI
10.1038/35007527
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Dimensions Publication ID
1049556603
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PubMed ID
10766252
1 reference
stated in
Europe PubMed Central
PubMed ID
10766252
retrieved
29 July 2017
ResearchGate publication ID
12550798
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