(Q33725835)

28 July 2017

title

Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines (English)

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genome-wide association study

28 July 2017

main subject

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10

Dieter Egli

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28 July 2017

Jin Yang

1

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28 July 2017

Yao Li

2

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28 July 2017

Lawrence Chan

3

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28 July 2017

Yi-Ting Tsai

4

1 reference

28 July 2017

Wen-Hsuan Wu

5

1 reference

28 July 2017

Huy V Nguyen

6

1 reference

28 July 2017

Chun-Wei Hsu

7

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28 July 2017

Xiaorong Li

8

1 reference

28 July 2017

Lewis M Brown

9

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28 July 2017

Janet R Sparrow

11

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28 July 2017

Stephen H Tsang

12

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28 July 2017

publication date

4 February 2014

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28 July 2017

published in

Human Molecular Genetics

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28 July 2017

volume

23

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28 July 2017

issue

13

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28 July 2017

page(s)

3445-3455

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describes a project that uses

28 July 2017

genome-wide association study

1 reference

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4049304/fullTextXML

inferred from PubMed Central ID database lookup

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Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations

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21 June 2018

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Oxidative stress, polyunsaturated fatty acids-derived oxidation products and bisretinoids as potential inducers of CNS diseases: focus on age-related macular degeneration

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa

21 June 2018

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21 June 2018

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Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosa.

21 June 2018

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Involvement of c-Abl, p53 and the MAP kinase JNK in the cell death program initiated in A2E-laden ARPE-19 cells by exposure to blue light

21 June 2018

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A2E, a pigment of RPE lipofuscin, is generated from the precursor, A2PE by a lysosomal enzyme activity

21 June 2018

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A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration

21 June 2018

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Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration

21 June 2018

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SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: implications for age-related macular degeneration

21 June 2018

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Functional interaction between beta-catenin and FOXO in oxidative stress signaling

21 June 2018

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RPE lipofuscin and its role in retinal pathobiology

21 June 2018

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Anthocyanins protect against A2E photooxidation and membrane permeabilization in retinal pigment epithelial cells

21 June 2018

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21 June 2018

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 June 2018

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Oxidative stress affects the junctional integrity of retinal pigment epithelial cells.

21 June 2018

1 reference

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A2E, a byproduct of the visual cycle

21 June 2018

1 reference

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Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration

21 June 2018

1 reference

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Ocular pathology in mitochondrial superoxide dismutase (Sod2)-deficient mice

21 June 2018

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Fluorescent pigments of the retinal pigment epithelium and age-related macular degeneration

21 June 2018

1 reference

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Oral supplementation of lutein/zeaxanthin and omega-3 long chain polyunsaturated fatty acids in persons aged 60 years or older, with or without AMD.

21 June 2018

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21 January 2018

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Simultaneous qualitative and quantitative analysis of the Escherichia coli proteome: a sweet tale

21 January 2018

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Cu-NirK from Haloferax mediterranei as an example of metalloprotein maturation and exportation via Tat system.

21 January 2018

1 reference

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Characterization of peroxy-A2E and furan-A2E photooxidation products and detection in human and mouse retinal pigment epithelial cell lipofuscin

21 January 2018

1 reference

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SOD2 knockdown mouse model of early AMD.

21 January 2018

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[The multiple roles of FOXO transcription factors]

21 January 2018

1 reference

12 December 2020

Lipofuscin and melanin of human retinal pigment epithelium. Fluorescence, enzyme cytochemical, and ultrastructural studies

1 reference

12 December 2020

Age pigment structure

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12 December 2020

The structure of the age pigment, lipofuscin, and its accumulation site in the human eye

1 reference

12 December 2020

Biomarkers of oxidative stress in patients with wet age related macular degeneration

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12 December 2020

Identifiers

DOI

10.1093/HMG/DDU053

1 reference

28 July 2017

1 reference

28 July 2017

1 reference