(Q33727606)

28 July 2017

title

Transcriptome of the GSH-Depleted Lens Reveals Changes in Detoxification and EMT Signaling Genes, Transport Systems, and Lipid Homeostasis (English)

1 reference

28 July 2017

0 references

Jeremy A Whitson

1

1 reference

28 July 2017

Xiang Zhang

2

1 reference

28 July 2017

Mario Medvedovic

3

1 reference

28 July 2017

Jenny Chen

4

1 reference

28 July 2017

Zongbo Wei

5

1 reference

28 July 2017

Vincent M Monnier

6

1 reference

28 July 2017

Xingjun Fan

7

1 reference

28 July 2017

language of work or name

English

0 references

publication date

1 May 2017

1 reference

Investigative Ophthalmology Visual Science

28 July 2017

published in

1 reference

28 July 2017

volume

58

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28 July 2017

issue

5

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28 July 2017

page(s)

2666-2684

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

28 July 2017

copyright license

start time

19 May 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Evidence of Dual Mechanisms of Glutathione Uptake in the Rodent Lens: A Novel Role for Vitreous Humor in Lens Glutathione Homeostasis

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Evidence of Highly Conserved β-Crystallin Disulfidome that Can be Mimicked by In Vitro Oxidation in Age-related Human Cataract and Glutathione Depleted Mouse Lens

21 June 2018

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21 June 2018

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21 June 2018

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Comparative transcriptome analysis of epithelial and fiber cells in newborn mouse lenses with RNA sequencing

21 June 2018

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Statin use and risk for cataract: a nested case-control study of 2 populations in Canada and the United States

21 June 2018

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21 June 2018

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PCSK9 and LDLR degradation: regulatory mechanisms in circulation and in cells

21 June 2018

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Splicing factor SRSF6 promotes hyperplasia of sensitized skin

21 June 2018

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Aging and age-related diseases of the ocular lens and vitreous body

21 June 2018

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Integrative analyses identify osteopontin, LAMB3 and ITGB1 as critical pro-metastatic genes for lung cancer.

21 June 2018

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Role of Nrf2 in oxidative stress and toxicity

21 June 2018

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The LEGSKO mouse: a mouse model of age-related nuclear cataract based on genetic suppression of lens glutathione synthesis

21 June 2018

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Redox regulation by Nrf2: gatekeeping for the basal and diabetes-induced expression of thioredoxin interacting protein

21 June 2018

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Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver

21 June 2018

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Identification of the preferentially targeted proteins by carbamylation during whole lens incubation by using radio-labelled potassium cyanate and mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Functions of cholesterol and the cholesterol bilayer domain specific to the fiber-cell plasma membrane of the eye lens.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Focus on molecules: ALDH1A1: from lens and corneal crystallin to stem cell marker.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Galanin and consummatory behavior: special relationship with dietary fat, alcohol and circulating lipids.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Alpha-synuclein is a cellular ferrireductase

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Suppression of injury-induced epithelial-mesenchymal transition in a mouse lens epithelium lacking tenascin-C

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Aldo-keto reductases in the eye.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Lens gap junctions in growth, differentiation, and homeostasis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Type I collagen promotes epithelial-mesenchymal transition through ILK-dependent activation of NF-kappaB and LEF-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Human aldehyde dehydrogenase genes: alternatively spliced transcriptional variants and their suggested nomenclature

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Human carboxylesterases: an update on CES1, CES2 and CES3.

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1(-/-)/Aldh1a1(-/-) knock-out mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Thioredoxin-like domain of human kappa class glutathione transferase reveals sequence homology and structure similarity to the theta class enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Identification and functional clustering of global gene expression differences between age-related cataract and clear human lenses and aged human lenses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Role of aldehyde dehydrogenase isozymes in the defense of rat lens and human lens epithelial cells against oxidative stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Analysis of the glutathione S-transferase (GST) gene family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Gene expression changes during cataract progression in Sparc null mice: differential regulation of mouse globins in the lens.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Gene expression profiling in human age-related nuclear cataract.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Molecular solutions to mammalian lens transparency.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Gene expression analysis of an H(2)O(2)-resistant lens epithelial cell line

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Glutathione: a vital lens antioxidant

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Antioxidant role of metallothioneins: a comparative overview

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Oxidative stress induces differential gene expression in a human lens epithelial cell line.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Role of lipid peroxidation in the pathogenesis of myopic and senile cataract

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Toxicity of iron and hydrogen peroxide: the Fenton reaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Urea formation in rat, bovine, and human lens.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Effects of ultraviolet light on the eye: role of protective glasses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Lens GABA receptors are a target of GABA-related agonists that mitigate experimental myopia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Transcriptomic signature to oxidative stress exposure at the time of embryonic genome activation in bovine blastocysts.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Persistent FoxE3 expression blocks cytoskeletal remodeling and organelle degradation during lens fiber differentiation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Carnosine protects against the inactivation of esterase induced by glycation and a steroid

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Increased content of zinc and iron in human cataractous lenses

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Oxidative stress and metallothionein expression in the liver of rats with severe thermal injury

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

SPARC deficiency leads to early-onset cataractogenesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5444549

Gene expression and discovery during lens regeneration in mouse: regulation of epithelial to mesenchymal transition and lens differentiation

30 October 2018

1 reference

12 December 2020

On the metallothionein, glutathione and cysteine relationship in rat liver

1 reference

12 December 2020

Posterior capsule opacification

1 reference

12 December 2020

In vitro study of gamma-glutamyl transpeptidase in rat lens

1 reference

12 December 2020

An impediment to glutathione diffusion in older normal human lenses: a possible precondition for nuclear cataract

1 reference

12 December 2020

p53 regulates epithelial-mesenchymal transition induced by transforming growth factor β

1 reference

12 December 2020

Lens metabolism and aging: enzyme activities and enzyme alterations in lenses of different species during the process of aging

1 reference

12 December 2020

Activity loss of glutathione synthesis enzymes associated with human subcapsular cataract

1 reference

12 December 2020

Identifiers

DOI

10.1167/IOVS.16-21398

1 reference

28 July 2017

1 reference

28 July 2017

1 reference