(Q28114922)

3 January 2017

title

Lanosterol reverses protein aggregation in cataracts (English)

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regulation of protein stability

3 January 2017

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ChEBI release 2020-05-28

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GOA release 2020-03-11

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GOA release 2020-03-11

protein aggregation

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Erratum: Corrigendum: Lanosterol reverses protein aggregation in cataracts

inferred from title

corrigendum / erratum

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26

Ruben Abagyan

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Jun Wang

object named as

Jun Wang

39

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Yong-Bin Yan

object named as

Yong-Bin Yan

Harry Christianto Tjondro

42

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object named as

Harry Christianto Tjondro

28

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author name string

Ling Zhao

1

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3 January 2017

Xiang-Jun Chen

2

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3 January 2017

Jie Zhu

3

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3 January 2017

Yi-Bo Xi

4

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3 January 2017

Xu Yang

5

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3 January 2017

Li-Dan Hu

6

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3 January 2017

Hong Ouyang

7

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3 January 2017

Sherrina H. Patel

8

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3 January 2017

Xin Jin

9

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3 January 2017

Danni Lin

10

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3 January 2017

Frances Wu

11

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3 January 2017

Ken Flagg

12

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3 January 2017

Huimin Cai

13

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3 January 2017

Gen Li

14

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3 January 2017

Guiqun Cao

15

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3 January 2017

Ying Lin

16

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3 January 2017

Daniel Chen

17

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3 January 2017

Cindy Wen

18

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3 January 2017

Christopher Chung

19

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3 January 2017

Yandong Wang

20

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3 January 2017

Austin Qiu

21

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3 January 2017

Emily Yeh

22

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3 January 2017

Wenqiu Wang

23

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3 January 2017

Xun Hu

24

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3 January 2017

Seanna Grob

25

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3 January 2017

Zhiguang Su

27

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3 January 2017

Xi-Juan Zhao

29

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3 January 2017

Hongrong Luo

30

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3 January 2017

Rui Hou

31

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3 January 2017

J. Jefferson

32

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3 January 2017

P. Perry

33

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3 January 2017

Weiwei Gao

34

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3 January 2017

Igor Kozak

35

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3 January 2017

David Granet

36

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3 January 2017

Yingrui Li

37

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3 January 2017

Xiaodong Sun

38

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3 January 2017

Liangfang Zhang

40

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3 January 2017

Yizhi Liu

41

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3 January 2017

Kang Zhang

43

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3 January 2017

language of work or name

English

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publication date

30 July 2015

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3 January 2017

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3 January 2017

volume

523

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3 January 2017

issue

7562

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3 January 2017

page(s)

607–611

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Global estimates of visual impairment: 2010.

3 January 2017

cites work

1 reference

12 December 2020

A novel mutation impairing the tertiary structure and stability of γC-crystallin (CRYGC) leads to cataract formation in humans and zebrafish lens.

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Crystallin proteins and amyloid fibrils

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Multiple molecular architectures of the eye lens chaperone B-crystallin elucidated by a triple hybrid approach

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Self-assembled lipid--polymer hybrid nanoparticles: a robust drug delivery platform.

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12 December 2020

Direct perturbation of lens membrane structure may contribute to cataracts caused by U18666A, an oxidosqualene cyclase inhibitor

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MutationTaster2: mutation prediction for the deep-sequencing age.

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12 December 2020

Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat

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12 December 2020

Protein misfolding and aggregation in cataract disease and prospects for prevention

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12 December 2020

Saffron administration prevents selenite-induced cataractogenesis

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Human fetal lens epithelial cells in culture: an in vitro model for the study of crystallin expression and lens differentiation

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12 December 2020

Fast and accurate long-read alignment with Burrows-Wheeler transform

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12 December 2020

Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

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12 December 2020

Cataracts: when to refer

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12 December 2020

A method and server for predicting damaging missense mutations

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12 December 2020

Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear

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12 December 2020

A framework for variation discovery and genotyping using next-generation DNA sequencing data

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12 December 2020

Optimal protocol and trajectory visualization for conformational searches of peptides and proteins

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12 December 2020

The monotopic membrane protein human oxidosqualene cyclase is active as monomer

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12 December 2020

Prevention of selenite-induced cataractogenesis by acetyl-L-carnitine: an experimental study

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12 December 2020

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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12 December 2020

Predicting deleterious amino acid substitutions

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12 December 2020

The benefits of being β-crystallin heteromers: βB1-crystallin protects βA3-crystallin against aggregation during co-refolding

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12 December 2020

Homology modeling by the ICM method

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12 December 2020

Conformational and functional differences between recombinant human lens alphaA- and alphaB-crystallin

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12 December 2020

Detection of nonneutral substitution rates on mammalian phylogenies

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12 December 2020

Differential gene expression in anatomical compartments of the human eye.

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12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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12 December 2020

The congenital cataract-linked A2V mutation impairs tetramer formation and promotes aggregation of βB2-crystallin

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12 December 2020

A novel CRYGD mutation (p.Trp43Arg) causing autosomal dominant congenital cataract in a Chinese family

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12 December 2020

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

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12 December 2020

A novel mutation in AlphaA-crystallin (CRYAA) caused autosomal dominant congenital cataract in a large Chinese family

1 reference

12 December 2020