(Q33728329)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

INSIG1 influences obesity-related hypertriglyceridemia in humans (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

1 reference

1

1 reference

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13 February 2020

Eric K Moses

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Lisa J. Martin

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Y Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

T M Baye

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

S Gawrieh

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

R Cole

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

J Blangero

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

M A Carless

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

J E Curran

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

T D Dyer

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

L J Abraham

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

A H Kissebah

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

M Olivier

14

1 reference

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13 February 2020

publication date

21 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

Journal of Lipid Research

13 February 2020

published in

1 reference

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13 February 2020

volume

51

1 reference

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13 February 2020

issue

4

1 reference

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13 February 2020

page(s)

701-708

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

Genomic convergence of genome-wide investigations for complex traits

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Protein sensors for membrane sterols

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Efficiency and power in genetic association studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

The Invader assay for SNP genotyping

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Haploview: analysis and visualization of LD and haplotype maps

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Hepatic insig-1 or -2 overexpression reduces lipogenesis in obese Zucker diabetic fatty rats and in fasted/refed normal rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Comparison of linkage analysis methods for genome-wide scanning of extended pedigrees, with application to the TG/HDL-C ratio in the Framingham Heart Study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Genome-wide scan on plasma triglyceride and high density lipoprotein cholesterol levels, accounting for the effects of correlated quantitative phenotypes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Genetic determinants of obesity-related lipid traits

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

High-throughput genotyping of single nucleotide polymorphisms using new biplex invader technology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

A risk factor for atherosclerosis: triglyceride-rich lipoproteins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Triglycerides: risk factor or fellow traveler?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

A major susceptibility locus influencing plasma triglyceride concentrations is located on chromosome 15q in Mexican Americans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Multipoint quantitative-trait linkage analysis in general pedigrees

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Cloning, human chromosomal assignment, and adipose and hepatic expression of the CL-6/INSIG1 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

An in vitro transcription analysis of early responses of the human immunodeficiency virus type 1 long terminal repeat to different transcriptional activators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Isolated low HDL cholesterol: an insulin-resistant state only in the presence of fasting hypertriglyceridemia.

21 June 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

Genetic and environmental influences on serum lipid levels in twins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

Familial resemblance of plasma lipids, lipoproteins and postheparin lipoprotein and hepatic lipases in the HERITAGE Family Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

A general approach to single-nucleotide polymorphism discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

A common genetic variant is associated with adult and childhood obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

The single nucleotide polymorphism upstream of insulin-induced gene 2 ( INSIG2) is associated with the prevalence of hypercholesterolaemia, but not with obesity, in Japanese American women

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

Impact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the PROVE IT-TIMI 22 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

Prevalence of high plasma triglyceride combined with low HDL-C levels and its association with smoking, hypertension, obesity, diabetes, sedentariness and LDL-C levels in the Canadian population. Canadian Heart Health Surveys Research Group.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838707

Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham Study

30 October 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

Combining probability from independent tests: the weighted Z-method is superior to Fisher's approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001404

A genome scan for serum triglyceride in obese nuclear families

21 January 2018

1 reference

12 December 2020

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes

1 reference

12 December 2020

Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man: Normolipemic subjects, familial hypertriglyceridemia and familial combined hyperlipidemia

1 reference

12 December 2020

Risk factors for coronary heart disease in adult female twins. Genetic heritability and shared environmental influences

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M001404

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19965593%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

19965593

1 reference