(Q33729380)

29 July 2017

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title

Factor VIIa interaction with endothelial cells and endothelial cell protein C receptor (English)

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29 July 2017

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Usha R Pendurthi

1

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29 July 2017

L Vijaya Mohan Rao

series ordinal

2

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29 July 2017

publication date

14 February 2010

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29 July 2017

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29 July 2017

volume

125 Suppl 1

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29 July 2017

page(s)

S19-22

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Bio-distribution of pharmacologically administered recombinant factor VIIa (rFVIIa)

29 July 2017

cites work

1 reference

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Coagulation factor Xa cleaves protease-activated receptor-1 and mediates signaling dependent on binding to the endothelial protein C receptor.

21 June 2018

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FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men

21 June 2018

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Endothelial cell protein C receptor cellular localization and trafficking: potential functional implications

21 June 2018

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Endothelial protein C receptor-assisted transport of activated protein C across the mouse blood-brain barrier

21 June 2018

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Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1.

21 June 2018

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Tissue factor and factor VIIa as therapeutic targets in disorders of hemostasis

21 June 2018

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The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

21 June 2018

1 reference

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Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium

21 June 2018

1 reference

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Multifunctional specificity of the protein C/activated protein C Gla domain.

21 June 2018

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Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow

21 June 2018

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Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

21 June 2018

1 reference

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Tissue factor-factor VIIa signaling

21 June 2018

1 reference

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21 June 2018

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Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

21 June 2018

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Activation of endothelial cell protease activated receptor 1 by the protein C pathway

21 June 2018

1 reference

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Characterization of protein C receptor expression in monocytes

21 June 2018

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Identification of the protein C/activated protein C binding sites on the endothelial cell protein C receptor. Implications for a novel mode of ligand recognition by a major histocompatibility complex class 1-type receptor

21 June 2018

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Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa x tissue factor-induced signal transduction

21 June 2018

1 reference

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Human protein C receptor is present primarily on endothelium of large blood vessels: implications for the control of the protein C pathway

21 June 2018

1 reference

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The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

21 June 2018

1 reference

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Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR). The structural and functional conservation in human, bovine, and murine EPCR

21 June 2018

1 reference

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Activated protein C decreases tumor necrosis factor related apoptosis-inducing ligand by an EPCR- independent mechanism involving Egr-1/Erk-1/2 activation

21 June 2018

1 reference

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Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2838982

Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin.

30 October 2018

1 reference

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PAR1 cleavage and signaling in response to activated protein C and thrombin.

30 October 2018

1 reference

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Dimorphisms in the membrane-spanning domain of EPCR impact systemic coagulation

30 October 2018

1 reference

12 December 2020

The number of receptors for factor VII correlates with the ability of cultured cells to initiate coagulation

1 reference

12 December 2020

Two independent binding sites on monolayers of human endothelial cells are responsible for interaction with coagulation factor VII and factor VIIa

1 reference

12 December 2020

Receptor-mediated endocytosis of coagulation factor Xa requires cell surface-bound tissue factor pathway inhibitor

1 reference

12 December 2020

The endothelial cell protein C receptor. Inhibition of activated protein C anticoagulant function without modulation of reaction with proteinase inhibitors

1 reference

12 December 2020

10.1016/J.THROMRES.2010.01.026

Identifiers

DOI

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29 July 2017

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29 July 2017

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