(Q33730082)

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Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action

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scholarly article

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action (English)

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Europe PubMed Central

29 July 2017

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McKerrow JH

1

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Europe PubMed Central

29 July 2017

publication date

1 June 1999

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Europe PubMed Central

29 July 2017

International Journal for Parasitology

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Europe PubMed Central

29 July 2017

29

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Europe PubMed Central

29 July 2017

6

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Europe PubMed Central

29 July 2017

833-837

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Europe PubMed Central

29 July 2017

The proteases and pathogenicity of parasitic protozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Analysis of the proteinases of Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Cysteine protease inhibitors as chemotherapy for parasitic infections

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Safety, pharmacokinetics, and antiretroviral activity of the potent, specific human immunodeficiency virus protease inhibitor nelfinavir: results of a phase I/II trial and extended follow-up in patients infected with human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Intracellular proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

The crystal structure of cruzain: a therapeutic target for Chagas' disease

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Proteases from Trypanosoma brucei brucei. Purification, characterisation and interactions with host regulatory molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Leishmania major: molecular modeling of cysteine proteases and prediction of new nonpeptide inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Cysteine protease inhibitors block schistosome hemoglobin degradation in vitro and decrease worm burden and egg production in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0020-7519%2899%2900044-2

7 January 2021

Identifiers

10.1016/S0020-7519(99)00044-2

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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