(Q33731898)

29 July 2017

1 reference

title

What geriatricians should know about the Werner syndrome (English)

1 reference

29 July 2017

Martin GM

1

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29 July 2017

Oshima J

series ordinal

2

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29 July 2017

Gray MD

series ordinal

3

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29 July 2017

Poot M

series ordinal

4

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29 July 2017

language of work or name

English

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publication date

1 September 1999

1 reference

Journal of the American Geriatrics Society

29 July 2017

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29 July 2017

47

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29 July 2017

1136-1144

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29 July 2017

9

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The Werner syndrome protein is a DNA helicase

29 July 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

A Review of its Symptomatology, Natural History, Pathologic Features, Genetics And Relationship to the Natural Aging Process

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Genetic linkage of Werner's syndrome to five markers on chromosome 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Positional cloning of the Werner's syndrome gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Werner's syndrome associated with malignancies: five case reports with a survey of case histories in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Mutator phenotype of Werner syndrome is characterized by extensive deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

The serial cultivation of human diploid cell strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Extension of life-span by introduction of telomerase into normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

DNA repair fine structure in Werner's syndrome cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

RecQ DNA helicase is a suppressor of illegitimate recombination in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Extrachromosomal rDNA circles--a cause of aging in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Nucleolar localization of the Werner syndrome protein in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Werner helicase is localized to transcriptionally active nucleoli of cycling cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Replication focus-forming activity 1 and the Werner syndrome gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

The three faces of the WS helicase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Structure and function of the human Werner syndrome gene promoter: evidence for transcriptional modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Detection by epitope-defined monoclonal antibodies of Werner DNA helicases in the nucleoplasm and their upregulation by cell transformation and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Studies on environmental chemical carcinogenesis in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Genetics and the pathobiology of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Pleiotropy, Natural Selection, and the Evolution of Senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

Genetic associations with human longevity at the APOE and ACE loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1532-5415.1999.TB05240.X

10.1111/J.1532-5415.1999.TB05240.X

21 January 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference