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mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
title
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
main subject
gluconeogenesis
1 reference
based on heuristic
inferred from title
corrigendum / erratum
Correction for Laplante et al., mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis
0 references
author
David M. Sabatini
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
author name string
Mathieu Laplante
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
language of work or name
English
0 references
publication date
18 February 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
volume
107
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
issue
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
page(s)
3281-3282
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
cites work
Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
retrieved
21 June 2018
An emerging role of mTOR in lipid biosynthesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
retrieved
21 June 2018
mTOR signaling at a glance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
retrieved
21 June 2018
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
AMP-activated protein kinase suppresses LXR-dependent sterol regulatory element-binding protein-1c transcription in rat hepatoma McA-RH7777 cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
retrieved
21 June 2018
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
retrieved
21 June 2018
The FoxO code
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
retrieved
21 June 2018
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
retrieved
21 June 2018
Selective versus total insulin resistance: a pathogenic paradox
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
retrieved
21 June 2018
AKT/PKB signaling: navigating downstream
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
SREBP-1c transcription factor and lipid homeostasis: clinical perspective
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
Inflammation and metabolic disorders
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840435
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21 June 2018
Can imaging techniques measure neuroprotection and remyelination in multiple sclerosis?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.1000323107
retrieved
21 January 2018
The mammalian target of rapamycin regulates lipid metabolism in primary cultures of rat hepatocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.1000323107
retrieved
21 January 2018
Role of the PI3-kinase/mTor pathway in the regulation of the stearoyl CoA desaturase (SCD1) gene expression by insulin in liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.1000323107
retrieved
21 January 2018
Identifiers
DOI
10.1073/PNAS.1000323107
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
ADS bibcode
2010PNAS..107.3281L
0 references
PMC publication ID
2840435
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PubMed publication ID
20167806
1 reference
stated in
Europe PubMed Central
PMC publication ID
2840435
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20167806%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
ResearchGate publication ID
41486443
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