(Q33735813)

English

In the absence of Sonic hedgehog, p53 induces apoptosis and inhibits retinal cell proliferation, cell-cycle exit and differentiation in zebrafish

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

29 July 2017

In the absence of Sonic hedgehog, p53 induces apoptosis and inhibits retinal cell proliferation, cell-cycle exit and differentiation in zebrafish (English)

1 reference

Europe PubMed Central

29 July 2017

0 references

author name string

Sergey V Prykhozhij

1

1 reference

Europe PubMed Central

29 July 2017

language of work or name

0 references

publication date

21 October 2010

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

5

1 reference

Europe PubMed Central

29 July 2017

10

1 reference

Europe PubMed Central

29 July 2017

e13549

1 reference

Europe PubMed Central

29 July 2017

copyright license

Creative Commons Attribution 4.0 International

21 October 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2958845/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The role of cell cycle in retinal development: cyclin-dependent kinase inhibitors co-ordinate cell-cycle inhibition, cell-fate determination and differentiation in the developing retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Hedgehog signaling in development and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Integrative genomic analyses on GLI2: mechanism of Hedgehog priming through basal GLI2 expression, and interaction map of stem cell signaling network with P53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Hedgehog: functions and mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Hedgehog serves as a mitogen and survival factor during embryonic stem cell neurogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Detection of the p53 response in zebrafish embryos using new monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Essential role of stromally induced hedgehog signaling in B-cell malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

The role of the SPT6 chromatin remodeling factor in zebrafish embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

p53 activation by knockdown technologies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Hedgehog signaling and the retina: insights into the mechanisms controlling the proliferative properties of neural precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Notch targets the Cdk inhibitor Xic1 to regulate differentiation but not the cell cycle in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Loss of function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Retinal ganglion cell-derived sonic hedgehog locally controls proliferation and the timing of RGC development in the embryonic mouse retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Hedgehogs as negative regulators of the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Death squads enlisted by the tumour suppressor p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

The emergent design of the neural tube: prepattern, SHH morphogen and GLI code

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Dependence receptors: what is the mechanism?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Extraretinal and retinal hedgehog signaling sequentially regulate retinal differentiation in zebrafish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Zebrafish as a model organism for the identification and characterization of drugs and genes affecting p53 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Hedgehog signaling in animal development: paradigms and principles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

The p57Kip2 cyclin kinase inhibitor is expressed by a restricted set of amacrine cells in the rodent retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Effective targeted gene 'knockdown' in zebrafish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Patterning of the zebrafish retina by a wave of sonic hedgehog activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Inhibition of sonic hedgehog signaling in vivo results in craniofacial neural crest cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Sonic hedgehog opposes epithelial cell cycle arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Sonic hedgehog controls epaxial muscle determination through Myf5 activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Sonic hedgehog regulates the growth and patterning of the cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Sonic hedgehog promotes rod photoreceptor differentiation in mammalian retinal cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Inhibition of protein kinase A phenocopies ectopic expression of hedgehog in the CNS of wild-type and cyclops mutant embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

Oncogenic forms of p53 inhibit p53-regulated gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

14 July 2018

A critical role for sonic hedgehog signaling in the early expansion of the developing brain

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Embryonic retinal gene expression in sonic-you mutant zebrafish

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Development. Longing for ligand: hedgehog, patched, and cell death.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Sonic hedgehog regulates proliferation of the retinal ciliary marginal zone in posthatch chicks

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Shh directs cell-cycle exit by activating p57Kip2 in the zebrafish retina

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Functional characterization of the Bcl-2 gene family in the zebrafish.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Suppression of apoptosis by bcl-2 overexpression in lymphoid cells of transgenic zebrafish.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Oligodendrocyte specification in zebrafish requires notch-regulated cyclin-dependent kinase inhibitor function.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Rb regulates proliferation and rod photoreceptor development in the mouse retina

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

p53 deficiency rescues apoptosis and differentiation of multiple cell types in zebrafish flathead mutants deficient for zygotic DNA polymerase delta1.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Mutation of zebrafish caf-1b results in S phase arrest, defective differentiation, and p53-mediated apoptosis during organogenesis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Method for isolation of PCR-ready genomic DNA from zebrafish tissues.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013549

21 January 2018

Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

30 October 2018

Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

30 October 2018

Co-ordinating retinal histogenesis: early cell cycle exit enhances early cell fate determination in the Xenopus retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

30 October 2018

A characterization of the effects of Dpp signaling on cell growth and proliferation in the Drosophila wing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

30 October 2018

Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

30 October 2018

Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2958845

30 October 2018

Double in situ hybridization techniques in zebrafish

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of apoptosis and differentiation by p53 in human embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-apoptotic role of Sonic hedgehog protein at the early stages of nervous system organogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p27Xic1, a Cdk inhibitor, promotes the determination of glial cells in Xenopus retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a p53 responsive GFP reporter; identification of live cells with p53 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0013549

1 reference

Europe PubMed Central

29 July 2017

2010PLoSO...513549P

0 references

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33735813&oldid=1869927769"