(Q33736396)

29 July 2017

title

In vivo discovery of immunotherapy targets in the tumour microenvironment (English)

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29 July 2017

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18

Nir Hacohen

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David E Root

15

object named as

David E Root

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29 July 2017

9

Glenn S Cowley

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29 July 2017

14

Hidde L Ploegh

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29 July 2017

Penghui Zhou

1

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29 July 2017

Donald R Shaffer

2

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29 July 2017

Diana A Alvarez Arias

3

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29 July 2017

Yukoh Nakazaki

4

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29 July 2017

Wouter Pos

5

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29 July 2017

Alexis J Torres

6

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29 July 2017

Viviana Cremasco

7

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29 July 2017

Stephanie K Dougan

8

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29 July 2017

Kutlu Elpek

10

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29 July 2017

Jennifer Brogdon

11

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29 July 2017

John Lamb

12

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29 July 2017

Shannon J Turley

13

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29 July 2017

J Christopher Love

16

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29 July 2017

Glenn Dranoff

17

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29 July 2017

Harvey Cantor

19

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29 July 2017

Kai W Wucherpfennig

20

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29 July 2017

language of work or name

English

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publication date

29 January 2014

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29 July 2017

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29 July 2017

volume

506

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29 July 2017

issue

7486

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29 July 2017

page(s)

52-57

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Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology

29 July 2017

cites work

1 reference

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Nivolumab plus ipilimumab in advanced melanoma

21 June 2018

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Tumor-infiltrating regulatory T cells: phenotype, role, mechanism of expansion in situ and clinical significance

21 June 2018

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Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells

21 June 2018

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Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.

21 June 2018

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Engineered T cells for anti-cancer therapy.

21 June 2018

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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

21 June 2018

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

21 June 2018

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Adoptive immunotherapy for cancer: harnessing the T cell response

21 June 2018

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Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

21 June 2018

1 reference

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Expression of tumour-specific antigens underlies cancer immunoediting

21 June 2018

1 reference

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Immune microenvironments in solid tumors: new targets for therapy

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Suppressors of cytokine signaling (SOCS) proteins and JAK/STAT pathways: regulation of T-cell inflammation by SOCS1 and SOCS3.

21 June 2018

1 reference

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Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Greatwall phosphorylates an inhibitor of protein phosphatase 2A that is essential for mitosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Dephosphorylation of Carma1 by PP2A negatively regulates T-cell activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Cbl-b in T-cell activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Adoptive T cell therapy of cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Intraepithelial CD8-positive T lymphocytes predict survival for patients with serous stage III ovarian carcinomas: relevance of clonal selection of T lymphocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Focus on TILs: prognostic significance of tumor infiltrating lymphocytes in human melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Myeloid-derived suppressor cells as regulators of the immune system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Highly parallel identification of essential genes in cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Tumor-specific Th17-polarized cells eradicate large established melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Molecular regulation of T-cell anergy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

JNK2 negatively regulates CD8+ T cell effector function and anti-tumor immune response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

A genetic screen for candidate tumor suppressors identifies REST

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Enhancement of antitumor immunity by CTLA-4 blockade

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

T cell receptor antagonist peptides induce positive selection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Biological behavior of malignant melanoma cells correlated to their survival in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Protein phosphatases and the regulation of mitosis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

Relevance of the tumor antigen in the validation of three vaccination strategies for melanoma

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4052214

30 October 2018

Identifiers

DOI

10.1038/NATURE12988

1 reference

29 July 2017

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29 July 2017

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