(Q33737606)

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Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiov

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scholarly article

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Europe PubMed Central

29 July 2017

Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiov (English)

1 reference

Europe PubMed Central

29 July 2017

circulatory system

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inferred from title

6

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Myriam Fornage

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Europe PubMed Central

29 July 2017

Deborah A Nickerson

12

object named as

Deborah A Nickerson

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Europe PubMed Central

29 July 2017

Leslie A. Lange

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object named as

Leslie A Lange

1 reference

Europe PubMed Central

29 July 2017

David R. Jacobs

11

object named as

David R Jacobs

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Europe PubMed Central

29 July 2017

author name string

Alexander P Reiner

1

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Europe PubMed Central

29 July 2017

Myron D Gross

2

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Europe PubMed Central

29 July 2017

Christopher S Carlson

3

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Europe PubMed Central

29 July 2017

Suzette J Bielinski

4

1 reference

Europe PubMed Central

29 July 2017

Nancy S Jenny

7

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29 July 2017

Jeremy Walston

8

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29 July 2017

Russell P Tracy

9

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29 July 2017

O Dale Williams

10

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29 July 2017

publication date

6 April 2009

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29 July 2017

Circulation: Cardiovascular Genetics

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Europe PubMed Central

29 July 2017

2

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29 July 2017

244-254

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29 July 2017

3

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Europe PubMed Central

29 July 2017

On the adjustment for covariates in genetic association analysis: a novel, simple principle to infer direct causal effects

1 reference

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New susceptibility locus for coronary artery disease on chromosome 3q22.3.

1 reference

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Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study

1 reference

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Common variants at 30 loci contribute to polygenic dyslipidemia

1 reference

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Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

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Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein

1 reference

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Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study

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Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

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Transcriptional complex formation of c-Fos, STAT3, and hepatocyte NF-1 alpha is essential for cytokine-driven C-reactive protein gene expression.

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Common variants in HNF-1 alpha and risk of type 2 diabetes

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Efficiency and power in genetic association studies

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Calcified coronary artery plaque measurement with cardiac CT in population-based studies: standardized protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) study.

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Is serum gamma glutamyltransferase a marker of oxidative stress?

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Control of pancreas and liver gene expression by HNF transcription factors

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Thrombin, inflammation, and cardiovascular disease: an epidemiologic perspective

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The search for type 2 diabetes susceptibility genes using whole-genome scans: an epidemiologist's perspective

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Hepatocyte nuclear factor-1alpha recruits the transcriptional co-activator p300 on the GLUT2 gene promoter

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Dissecting the transcriptional network of pancreatic islets during development and differentiation

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Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841292

21 June 2018

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young

1 reference

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Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

1 reference

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Hepatocyte nuclear factor 1, a transcription factor at the crossroads of glucose homeostasis.

1 reference

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Role of general and gene-specific cofactors in the regulation of eukaryotic transcription

1 reference

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Liver-enriched transcription factors and hepatocyte differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841292

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Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome

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An indirect negative autoregulatory mechanism involved in hepatocyte nuclear factor-1 gene expression.

1 reference

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More potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processing

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Synergistic trans-activation of the human C-reactive protein promoter by transcription factor HNF-1 binding at two distinct sites.

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Characterization of tissue-specific enhancer elements in the second intron of the human apolipoprotein B gene

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HNF-1 shares three sequence motifs with the POU domain proteins and is identical to LF-B1 and APF.

1 reference

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1 reference

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1 reference

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A Genome Search for Genetic Determinants That Influence Plasma Fibrinogen Levels

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The transcription factor HNF1 acts with C/EBP alpha to synergistically activate the human albumin promoter through a novel domain

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Laboratory methods and quality assurance in the Cardiovascular Health Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20031592

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Surveillance and ascertainment of cardiovascular events. The Cardiovascular Health Study

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https://pubmed.ncbi.nlm.nih.gov/20031592

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Identifiers

10.1161/CIRCGENETICS.108.839506

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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