(Q33740176)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Kishan J Patel

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Michael Churchill

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Ralph Weissleder

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

21

Kenneth C Anderson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

22

David T Scadden

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Sonia Vallet

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Siddhartha Mukherjee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Nileshwari Vaghela

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Teru Hideshima

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Mariateresa Fulciniti

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Loredana Santo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Diana Cirstea

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Aliyah R Sohani

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Alex Guimaraes

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Wanling Xie

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Dharminder Chauhan

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Jesse A Schoonmaker

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Eyal Attar

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Edie Weller

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Nikhil Munshi

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Jasbir S Seehra

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Noopur Raje

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

1 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

5124-5129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

A soluble activin type IIA receptor induces bone formation and improves skeletal integrity

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

The beta1 integrin activates JNK independent of CagA, and JNK activation is required for Helicobacter pylori CagA+-induced motility of gastric cancer cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Changes in extracellular activin A:follistatin ratio during differentiation of a mesenchymal progenitor cell line, ROB-C26 into osteoblasts and adipocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Cancer metastasis: building a framework

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

New potential targets for treating myeloma bone disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

TGF-beta promotes the establishment of renal cell carcinoma bone metastasis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems and a myelomatous mouse model

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

A clinically relevant SCID-hu in vivo model of human multiple myeloma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Regulation of osteoblastogenesis and bone mass by Wnt10b

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Reconstitution and analysis of soluble inhibin and activin receptor complexes in a cell-free system

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Inhibin suppresses and activin stimulates osteoblastogenesis and osteoclastogenesis in murine bone marrow cultures

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Antisense inhibition of macrophage inflammatory protein 1-alpha blocks bone destruction in a model of myeloma bone disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

TGF-beta signaling in tumor suppression and cancer progression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclast-stimulating activity.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Human activin betaA gene. Identification of novel 5' exon, functional promoter, and enhancers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Single-dose, randomized, double-blind, placebo-controlled study of ACE-011 (ActRIIA-IgG1) in postmenopausal women

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Dlx5, a positive regulator of osteoblastogenesis, is essential for osteoblast-osteoclast coupling.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

The activin A-follistatin system: potent regulator of human extracellular matrix mineralization

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

BMP signals regulate Dlx5 during early avian skull development

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Calcium-regulated expression of activin A in RBL-2H3 mast cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Activin A is an essential cofactor for osteoclast induction.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

Regulation of cellular and system function by activin

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841922

CONTRASTING EFFECTS OF INFLAMMATROY CYTOKINES AND GLUCOCORTICOIDS ON THE PRODUCTION OF ACTIVIN A IN HUMAN MARROW STROMAL CELLS AND THEIR IMPLICATIONS

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20194748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibin A is an endocrine stimulator of bone mass and strength

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20194748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibitory effects of activin-A on osteoblast differentiation during cultures of fetal rat calvarial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20194748

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0911929107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20194748%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

20194748

1 reference