(Q33741183)

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Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21059263%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21059263%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

medulloblastoma

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Javier S. Castresana

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21059263%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Charles G Eberhart

4

object named as

Charles G Eberhart

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Europe PubMed Central

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16 January 2020

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Mehdi H Shahi

1

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16 January 2020

Mohammad Afzal

2

1 reference

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16 January 2020

Subrata Sinha

3

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16 January 2020

Juan A Rey

5

1 reference

Europe PubMed Central

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16 January 2020

Xing Fan

6

1 reference

Europe PubMed Central

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16 January 2020

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publication date

8 November 2010

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Europe PubMed Central

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16 January 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21059263%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

10

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Europe PubMed Central

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16 January 2020

614

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21059263%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Hedgehog signalling in medulloblastoma, glioblastoma and neuroblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor: effects on gene expression and growth of glioma cells in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

PAX6 suppresses the invasiveness of glioblastoma cells and the expression of the matrix metalloproteinase-2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

A model for PTCH1/Ptch1-associated tumors comprising mutational inactivation and gene silencing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Morphing into cancer: the role of developmental signaling pathways in brain tumor formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Interference with HH-GLI signaling inhibits prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

PAX6 suppresses growth of human glioblastoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Medulloblastoma: developmental mechanisms out of control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

From neural stem cells to myelinating oligodendrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Sonic hedgehog regulates the growth and patterning of the cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Increased expression of cyclin D2 during multiple states of growth arrest in primary and established cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Stability of patch methylation and its impact in regions of transcriptional initiation and elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Functional analysis of the human cyclin D2 and cyclin D3 promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Deregulated expression of PAX5 in medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Pax-6, a murine paired box gene, is expressed in the developing CNS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989332

14 July 2018

Medulloblastoma growth inhibition by hedgehog pathway blockade

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-614

21 January 2018

Functional Smoothened is required for expression of GLI3 in colorectal carcinoma cells

1 reference

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21 January 2018

Relevance of combinatorial profiles of intermediate filaments and transcription factors for glioma histogenesis

1 reference

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21 January 2018

Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma.

1 reference

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21 January 2018

Identification and characterization of multiple isoforms of a murine and human tumor suppressor, patched, having distinct first exons

1 reference

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21 January 2018

Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers.

1 reference

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21 January 2018

Correlation of gamma-catenin expression with good prognosis in medulloblastomas.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-614

21 January 2018

Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation

1 reference

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12 December 2020

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10.1186/1471-2407-10-614

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21059263%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21059263%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21059263%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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