(Q33741229)

29 July 2017

title

A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion (English)

1 reference

29 July 2017

1 reference

Soonkyu Chung

1

1 reference

29 July 2017

Abraham K Gebre

2

1 reference

29 July 2017

Jeongmin Seo

3

1 reference

29 July 2017

Gregory S Shelness

4

1 reference

29 July 2017

John S Parks

5

1 reference

29 July 2017

language of work or name

1 reference

1 April 2010

1 reference

Journal of Lipid Research

29 July 2017

published in

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29 July 2017

volume

51

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29 July 2017

issue

4

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29 July 2017

page(s)

729-742

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Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL.

29 July 2017

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1 reference

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

21 June 2018

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ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

21 June 2018

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21 June 2018

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The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis

21 June 2018

1 reference

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Role of LXRs in control of lipogenesis

21 June 2018

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Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes.

21 June 2018

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21 June 2018

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Rat McA-RH7777 cells efficiently assemble rat apolipoprotein B-48 or larger fragments into VLDL but not human apolipoprotein B of any size

21 June 2018

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21 June 2018

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The activity of microsomal triglyceride transfer protein is essential for accumulation of triglyceride within microsomes in McA-RH7777 cells. A unified model for the assembly of very low density lipoproteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

21 June 2018

1 reference

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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

21 June 2018

1 reference

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Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

21 June 2018

1 reference

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Phosphoinositide 3-kinase activity is necessary for insulin-dependent inhibition of apolipoprotein B secretion by rat hepatocytes and localizes to the endoplasmic reticulum

21 June 2018

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Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes

21 June 2018

1 reference

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Studies on the assembly of apolipoprotein B-100- and B-48-containing very low density lipoproteins in McA-RH7777 cells.

21 June 2018

1 reference

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LXR, a nuclear receptor that defines a distinct retinoid response pathway

21 June 2018

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Cholesterol is required for the secretion of the very-low-density lipoprotein: in vivo studies

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Effect of fish oil diet on hepatic lipid metabolism in nonhuman primates: lowering of secretion of hepatic triglyceride but not apoB.

21 June 2018

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Isolation and characterization of an apoA-II-containing lipoprotein (LP-A-II:B complex) from plasma very low density lipoproteins of patients with Tangier disease and type V hyperlipoproteinemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Hydrolysis of neutral lipid substrates by rat hepatic lipase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Conformational and thermodynamic properties of apo A-1 of human plasma high density lipoproteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Quantitative analysis of ABCA1-dependent compartmentalization and trafficking of apolipoprotein A-I: implications for determining cellular kinetics of nascent high density lipoprotein biogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Identification of an ABCA1-dependent phospholipid-rich plasma membrane apolipoprotein A-I binding site for nascent HDL formation: implications for current models of HDL biogenesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Minimal lipidation of pre-beta HDL by ABCA1 results in reduced ability to interact with ABCA1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

PI3-kinase activity modulates apo B available for hepatic VLDL production in apobec-1-/- mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Rapamycin, an mTOR inhibitor, disrupts triglyceride metabolism in guinea pigs.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Overproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Prebeta high density lipoprotein has two metabolic fates in human apolipoprotein A-I transgenic mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Identification of the lipoprotein initiating domain of apolipoprotein B.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Sirolimus changes lipid concentrations and lipoprotein metabolism in kidney transplant recipients

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Regulation of microsomal triglyceride transfer protein gene by insulin in HepG2 cells: roles of MAPKerk and MAPKp38.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Insulin inhibits the maturation phase of VLDL assembly via a phosphoinositide 3-kinase-mediated event

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

The assembly and secretion of apolipoprotein B-48-containing very low density lipoproteins in McA-RH7777 cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842152

Insulin effects on apolipoprotein B lipoprotein synthesis and secretion by primary cultures of rat hepatocytes

30 October 2018

1 reference

12 December 2020

Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: insulin negatively regulates MTP gene expression

1 reference

12 December 2020

Cholesteryl ester transfer protein activity enhances plasma cholesteryl ester formation. Studies in CETP transgenic mice and human genetic CETP deficiency

1 reference

12 December 2020

Lecithin-cholesterol acyltransferase. Assay of cholesterol esterification and phospholipase A2 activities

1 reference

12 December 2020

Subpopulations of high density lipoproteins in homozygous and heterozygous Tangier disease

1 reference

12 December 2020

Diabetic dyslipidaemia

1 reference

12 December 2020

Ratio determination of plasma wild-type and L159R apoA-I using mass spectrometry: tools for studying apoA-IFin

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M900083

1 reference

29 July 2017

1 reference

29 July 2017

1 reference