(Q33743195)

English

Streptococcus mutans extracellular DNA is upregulated during growth in biofilms, actively released via membrane vesicles, and influenced by components of the protein secretion machinery

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14 March 2020

Streptococcus mutans extracellular DNA is upregulated during growth in biofilms, actively released via membrane vesicles, and influenced by components of the protein secretion machinery (English)

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Europe PubMed Central

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14 March 2020

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Streptococcus mutans

object named as

Streptococcus mutans

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Marlise I. Klein

2

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14 March 2020

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14 March 2020

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14 March 2020

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Sumei Liao

1

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14 March 2020

Kyle P Heim

3

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14 March 2020

Jacob P Bitoun

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14 March 2020

San-Joon Ahn

6

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14 March 2020

Hyun Koo

8

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14 March 2020

L Jeannine Brady

9

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14 March 2020

Zezhang T Wen

10

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14 March 2020

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18 April 2014

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14 March 2020

Journal of Bacteriology

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14 March 2020

196

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14 March 2020

13

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14 March 2020

2355-2366

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14 March 2020

Bacterial social networks: structure and composition of Myxococcus xanthus outer membrane vesicle chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Streptococcus mutans: a new Gram-positive paradigm?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

DNA builds and strengthens the extracellular matrix in Myxococcus xanthus biofilms by interacting with exopolysaccharides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Role of Pseudomonas aeruginosa peptidoglycan-associated outer membrane proteins in vesicle formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Functional amyloid formation by Streptococcus mutans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Identification of the Streptococcus mutans LytST two-component regulon reveals its contribution to oxidative stress tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Enterococcus faecalis produces abundant extracellular structures containing DNA in the absence of cell lysis during early biofilm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

YidC1 and YidC2 are functionally distinct proteins involved in protein secretion, biofilm formation and cariogenicity of Streptococcus mutans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

The exopolysaccharide matrix modulates the interaction between 3D architecture and virulence of a mixed-species oral biofilm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Impact of extracellular nuclease production on the biofilm phenotype of Staphylococcus aureus under in vitro and in vivo conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

BrpA is involved in regulation of cell envelope stress responses in Streptococcus mutans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Staphylococcus aureus produces membrane-derived vesicles that induce host cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Hydrogen peroxide-dependent DNA release and transfer of antibiotic resistance genes in Streptococcus gordonii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Role of glucosyltransferase B in interactions of Candida albicans with Streptococcus mutans and with an experimental pellicle on hydroxyapatite surfaces.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

The major autolysin of Streptococcus gordonii is subject to complex regulation and modulates stress tolerance, biofilm formation, and extracellular-DNA release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Biology of Streptococcus mutans-derived glucosyltransferases: role in extracellular matrix formation of cariogenic biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Transcriptome analysis of LuxS-deficient Streptococcus mutans grown in biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Dynamics of Streptococcus mutans transcriptome in response to starch and sucrose during biofilm development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Protocols to study the physiology of oral biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

The Streptococcus mutans Cid and Lrg systems modulate virulence traits in response to multiple environmental signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Exopolysaccharides produced by Streptococcus mutans glucosyltransferases modulate the establishment of microcolonies within multispecies biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Role of extracellular DNA during biofilm formation by Listeria monocytogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Amyloid fibers provide structural integrity to Bacillus subtilis biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Cell death in Streptococcus mutans biofilms: a link between CSP and extracellular DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Streptococcus adherence and colonization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Characterization of hydrogen peroxide-induced DNA release by Streptococcus sanguinis and Streptococcus gordonii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Contribution of autolysin and Sortase a during Enterococcus faecalis DNA-dependent biofilm development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

A fratricidal mechanism is responsible for eDNA release and contributes to biofilm development of Enterococcus faecalis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Independent gene duplications of the YidC/Oxa/Alb3 family enabled a specialized cotranslational function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

DNA as an adhesin: Bacillus cereus requires extracellular DNA to form biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Characteristics of biofilm formation by Streptococcus mutans in the presence of saliva.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Effects of oxygen on virulence traits of Streptococcus mutans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Glucan-binding proteins are essential for shaping Streptococcus mutans biofilm architecture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Membrane composition changes and physiological adaptation by Streptococcus mutans signal recognition particle pathway mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

The atlA operon of Streptococcus mutans: role in autolysin maturation and cell surface biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Influence of BrpA on critical virulence attributes of Streptococcus mutans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Influence of apigenin on gtf gene expression in Streptococcus mutans UA159.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Streptococcal viability and diminished stress tolerance in mutants lacking the signal recognition particle pathway or YidC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Involvement of sortase anchoring of cell wall proteins in biofilm formation by Streptococcus mutans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

A hypothetical protein of Streptococcus mutans is critical for biofilm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Trigger factor in Streptococcus mutans is involved in stress tolerance, competence development, and biofilm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

DNA-containing membrane vesicles of Pseudomonas aeruginosa PAO1 and their genetic transformation potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

LuxS-mediated signaling in Streptococcus mutans is involved in regulation of acid and oxidative stress tolerance and biofilm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Death's toolbox: examining the molecular components of bacterial programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Glucan-binding proteins of the oral streptococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Roles of sortase in surface expression of the major protein adhesin P1, saliva-induced aggregation and adherence, and cariogenicity of Streptococcus mutans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Functional genomics approach to identifying genes required for biofilm development by Streptococcus mutans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Extracellular DNA Required for Bacterial Biofilm Formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Streptococcus gordonii biofilm formation: identification of genes that code for biofilm phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Regulation of expression of the fructan hydrolase gene of Streptococcus mutans GS-5 by induction and carbon catabolite repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Virulence of a spaP mutant of Streptococcus mutans in a gnotobiotic rat model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Oral streptococci... products of their environment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Electron microscopy during release and purification of mesosomal vesicles and protoplast membranes from Staphylococcus aureus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Isolation and characterization of monoclonal antibodies specific for antigen P1, a major surface protein of mutans streptococci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Molecular cloning and expression of a Streptococcus mutans major surface protein antigen, P1 (I/II), in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Manipulations of cellular iron metabolism for modulating normal and malignant cell proliferation: achievements and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Role of a cell surface-associated protein in adherence and dental caries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Glucans synthesized in situ in experimental salivary pellicle function as specific binding sites for Streptococcus mutans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

Growth of several cariogenic strains of oral streptococci in a chemically defined medium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

21 June 2018

A novel function for the competence inducing peptide, XIP, as a cell death effector of Streptococcus mutans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

Biofilms can be dispersed by focusing the immune system on a common family of bacterial nucleoid-associated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

A dual role of extracellular DNA during biofilm formation of Neisseria meningitidis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

Consequences of a sortase A mutation in Streptococcus gordonii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

Membrane vesicles traffic signals and facilitate group activities in a prokaryote

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

DNA binding-uptake system: a link between cell-to-cell communication and biofilm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

Neisseria gonorrhoeae secretes chromosomal DNA via a novel type IV secretion system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

An ffh mutant of Streptococcus mutans is viable and able to physiologically adapt to low pH in continuous culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

Roles of Streptococcus mutans dextranase anchored to the cell wall by sortase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

The sortase of Streptococcus mutans mediates cell wall anchoring of a surface protein antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4054167

30 October 2018

Binding properties of streptococcal glucosyltransferases for hydroxyapatite, saliva-coated hydroxyapatite, and bacterial surfaces

1 reference

https://pubmed.ncbi.nlm.nih.gov/24748612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Action of agents on glucosyltransferases from Streptococcus mutans in solution and adsorbed to experimental pellicle

1 reference

https://pubmed.ncbi.nlm.nih.gov/24748612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of eDNA on the adhesion forces between Streptococcus mutans and substratum surfaces: influence of ionic strength and substratum hydrophobicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24748612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of glucan-binding protein C reduces the cariogenicity of Streptococcus mutans: analysis of strains isolated from human blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/24748612

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JB.01493-14

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24748612%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24748612%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24748612%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

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