(Q33747406)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

0 references

1 reference

6

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18 January 2020

Alan V. Boddy

7

1 reference

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18 January 2020

author name string

J Bray

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

J Sludden

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

M J Griffin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

M Cole

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

M Verrill

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

language of work or name

English

0 references

publication date

23 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Cancer

18 January 2020

published in

1 reference

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18 January 2020

volume

102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

6

1 reference

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18 January 2020

page(s)

1003-1009

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6605587

18 January 2020

exact match

0 references

cites work

Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa

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Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide

21 June 2018

1 reference

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Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trials

21 June 2018

1 reference

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A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844036

Characterization of the organic cation transporter SLC22A16: a doxorubicin importer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844036

Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3)

21 June 2018

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A single nucleotide polymorphism of CYP2b6 found in Japanese enhances catalytic activity by autoactivation

21 June 2018

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Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease

21 June 2018

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Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment

21 June 2018

1 reference

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Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844036

Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844036

Identification of the polymorphically expressed CYP2C19 and the wild-type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosfamide activation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844036

The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans

21 June 2018

1 reference

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Mechanism of multidrug resistance

21 June 2018

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Isolation of amplified and overexpressed DNA sequences from adriamycin-resistant human breast cancer cells.

21 June 2018

1 reference

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Identification and functional characterization of eight CYP3A4 protein variants

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605587

Functional characterization of cytochrome P450 2B6 allelic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605587

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6605587

Association of high T allele frequency of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine

21 January 2018

1 reference

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Cytochrome P450 pharmacogenetics as a predictor of toxicity and clinical response to pulse cyclophosphamide in lupus nephritis

21 January 2018

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Antimycotic drug discovery in the age of genomics

21 January 2018

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Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial

21 January 2018

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Pharmacogenetics of cyclophosphamide in patients with hematological malignancies

21 January 2018

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Baculovirus vectors: novel mammalian cell gene-delivery vehicles and their applications

21 January 2018

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Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

21 January 2018

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ABCB1 and GST polymorphisms associated with TP53 status in breast cancer

30 October 2018

1 reference

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Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes

21 January 2018

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Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, methotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: results

30 October 2018

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12 December 2020

Polychemotherapy for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group

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12 December 2020

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

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12 December 2020

Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study

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12 December 2020

Association of cyclophosphamide pharmacokinetics to polymorphic cytochrome P450 2C19

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12 December 2020

Genetic polymorphisms of CYP2B6 affect the pharmacokinetics/pharmacodynamics of cyclophosphamide in Japanese cancer patients

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12 December 2020

Novel SLC22A16 polymorphisms and influence on doxorubicin pharmacokinetics in Asian breast cancer patients

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12 December 2020

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

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12 December 2020

Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6605587

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20179710%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

20179710

1 reference