(Q33747569)

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Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079681%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079681%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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16 January 2020

Lisbeth A Guethlein

4

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Lisbeth A Guethlein

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16 January 2020

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Laurent Abi-Rached

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16 January 2020

Raja Rajalingam

3

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16 January 2020

Peter Parham

5

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16 January 2020

publication date

4 November 2010

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16 January 2020

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Europe PubMed Central

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16 January 2020

6

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16 January 2020

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16 January 2020

e1001192

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16 January 2020

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Creative Commons Attribution 4.0 International

4 November 2010

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April 2022 Public Data File from Crossref

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Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 epitope of MHC class I

1 reference

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21 June 2018

Chimpanzees in hepatitis C virus research: 1998-2007.

1 reference

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21 June 2018

Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands

1 reference

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21 June 2018

A novel system of polymorphic and diverse NK cell receptors in primates

1 reference

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21 June 2018

Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies.

1 reference

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21 June 2018

DnaSP v5: a software for comprehensive analysis of DNA polymorphism data

1 reference

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21 June 2018

Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Human natural killer receptors, co-receptors, and their ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

NK receptor interactions with MHC class I molecules in pregnancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Balancing selection and heterogeneity across the classical human leukocyte antigen loci: a meta-analytic review of 497 population studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

The Yin and Yang of HLA and KIR in human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Functions of natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Up on the tightrope: natural killer cell activation and inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Evolutionary struggles between NK cells and viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Evolutionarily conserved amino acids that control TCR-MHC interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

A single bottleneck in HLA-C assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Protein kinase C regulates expression and function of inhibitory killer cell Ig-like receptors in NK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Haplotype inference for present-absent genotype data using previously identified haplotypes and haplotype patterns.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Effector and regulatory events during natural killer-dendritic cell interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Going east: new genetic and archaeological perspectives on the modern human colonization of Eurasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

The killer immunoglobulin-like receptor gene cluster: tuning the genome for defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Genomic evolution of MHC class I region in primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Understanding how combinations of HLA and KIR genes influence disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

MHC class I molecules and KIRs in human history, health and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

IPD--the Immuno Polymorphism Database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Kinase peptide specificity: improved determination and relevance to protein phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

New allele frequency database: http://www.allelefrequencies.net

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP-2) Can Play a Direct Role in the Inhibitory Function of Killer Cell Ig-Like Receptors in Human NK Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Sequencing the chimpanzee genome: insights into human evolution and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

The innate immune response to tumors and its role in the induction of T-cell immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Natural killer cells and pregnancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Natural killer cell immunoglobulin-like receptor (KIR) locus profiles in African and South Asian populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

DIVERGE: phylogeny-based analysis for functional-structural divergence of a protein family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

KIR: diverse, rapidly evolving receptors of innate and adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Conservation and variation in human and common chimpanzee CD94 and NKG2 genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Divergent and convergent evolution of NK-cell receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Common chimpanzees have greater diversity than humans at two of the three highly polymorphic MHC class I genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Plasticity in the organization and sequences of human KIR/ILT gene families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

The human natural killer cell immune synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

PAML: a program package for phylogenetic analysis by maximum likelihood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Determination of the specific substrate sequence motifs of protein kinase C isozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

A roadmap for HLA-A, HLA-B, and HLA-C peptide binding specificities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

The inter-locus recombinant HLA-B*4601 has high selectivity in peptide binding and functions characteristic of HLA-C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

The HLA-B73 antigen has a most unusual structure that defines a second lineage of HLA-B alleles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Diversity and diversification of HLA-A,B,C alleles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Distinctive polymorphism at the HLA-C locus: implications for the expression of HLA-C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

21 June 2018

Evolution of killer cell Ig-like receptor (KIR) genes: definition of an orangutan KIR haplotype reveals expansion of lineage III KIR associated with the emergence of MHC-C.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001192

21 January 2018

Brain size at birth throughout human evolution: a new method for estimating neonatal brain size in hominins

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001192

21 January 2018

HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001192

21 January 2018

Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001192

21 January 2018

KIR2DL5 alleles mark certain combination of activating KIR genes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001192

21 January 2018

SNP haplotypes and allele frequencies show evidence for disruptive and balancing selection in the human leukocyte receptor complex

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001192

21 January 2018

Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2973822

30 October 2018

Duplication, mutation and recombination of the human orphan gene KIR2DS3 contribute to the diversity of KIR haplotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21079681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21079681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominance of group A KIR haplotypes in Japanese associated with diverse NK cell repertoires of KIR expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21079681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High KIR diversity in Amerindians is maintained using few gene-content haplotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21079681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expanded cattle KIR genes are orthologous to the conserved single-copy KIR3DX1 gene of primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/21079681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PGEN.1001192

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079681%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079681%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21079681%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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