(Q33748844)

29 July 2017

title

Rapamycin is neuroprotective in a rat chronic hypertensive glaucoma model (English)

1 reference

29 July 2017

1 reference

Wenru Su

1

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author name string

Zuohong Li

series ordinal

2

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29 July 2017

Yu Jia

series ordinal

3

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29 July 2017

Yehong Zhuo

series ordinal

4

1 reference

29 July 2017

language of work or name

English

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publication date

12 June 2014

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29 July 2017

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29 July 2017

volume

9

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29 July 2017

issue

6

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29 July 2017

page(s)

e99719

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Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

12 June 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Autophagy in retinal ganglion cells in a rhesus monkey chronic hypertensive glaucoma model

28 July 2018

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28 July 2018

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Activation of Autophagy Pathway Suppresses the Expression of iNOS, IL6 and Cell Death of LPS-Stimulated Microglia Cells

28 July 2018

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The extent of synaptic stripping of motoneurons after axotomy is not correlated to activation of surrounding glia or downregulation of postsynaptic adhesion molecules.

28 July 2018

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M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells

28 July 2018

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Early reduction of microglia activation by irradiation in a model of chronic glaucoma

28 July 2018

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28 July 2018

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28 July 2018

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Activation of autophagy induces retinal ganglion cell death in a chronic hypertensive glaucoma model

28 July 2018

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The molecular basis of retinal ganglion cell death in glaucoma

28 July 2018

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28 July 2018

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Activation of autophagy in a rat model of retinal ischemia following high intraocular pressure

28 July 2018

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Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina

28 July 2018

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In glaucoma the upregulated truncated TrkC.T1 receptor isoform in glia causes increased TNF-alpha production, leading to retinal ganglion cell death

28 July 2018

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The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease

28 July 2018

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Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS

28 July 2018

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Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation

28 July 2018

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Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

28 July 2018

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An agonistic TrkB mAb causes sustained TrkB activation, delays RGC death, and protects the retinal structure in optic nerve axotomy and in glaucoma

28 July 2018

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28 July 2018

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28 July 2018

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Cilostazol is anti-inflammatory in BV2 microglial cells by inactivating nuclear factor-kappaB and inhibiting mitogen-activated protein kinases.

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability

28 July 2018

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Inhibition of p75(NTR) in glia potentiates TrkA-mediated survival of injured retinal ganglion cells

28 July 2018

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Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

On the action of cyclosporine A, rapamycin and tacrolimus on M. avium including subspecies paratuberculosis

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

PI3K: downstream AKTion blocks apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Regulation of neuronal survival by the serine-threonine protein kinase Akt

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Rapamycin is a neuroprotective treatment for traumatic brain injury.

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099719

Neuroprotective effect of melatonin against hypoxia-induced retinal ganglion cell death in neonatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099719

Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099719

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099719

Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099719

Regulation of cell death and survival pathways in experimental glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099719

Retinal ganglion cell death is delayed by activation of retinal intrinsic cell survival program

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099719

Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099719

Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0099719

Detection of early neuron degeneration and accompanying microglial responses in the retina of a rat model of glaucoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4055719

Quantitation of nitrate and nitrite in extracellular fluids

30 October 2018

1 reference

12 December 2020

Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain

1 reference

12 December 2020

Activated microglia in the human glaucomatous optic nerve head

1 reference

12 December 2020

Neurotrophic rationale in glaucoma: a TrkA agonist, but not NGF or a p75 antagonist, protects retinal ganglion cells in vivo

1 reference

12 December 2020

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12 December 2020

Doxycycline-mediated inhibition of corneal angiogenesis: an MMP-independent mechanism

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0099719

Identifiers

DOI

1 reference

29 July 2017

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29 July 2017

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