(Q33750163)

29 July 2017

title

Phosphoproteomics-based modeling defines the regulatory mechanism underlying aberrant EGFR signaling (English)

1 reference

29 July 2017

Noriko Gotoh

5

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author name string

Shinya Tasaki

1

1 reference

29 July 2017

Masao Nagasaki

2

1 reference

29 July 2017

Hiroko Kozuka-Hata

3

1 reference

29 July 2017

Kentaro Semba

4

1 reference

29 July 2017

Seisuke Hattori

6

1 reference

29 July 2017

Jun-ichiro Inoue

7

1 reference

29 July 2017

Tadashi Yamamoto

8

1 reference

29 July 2017

Satoru Miyano

9

1 reference

29 July 2017

Sumio Sugano

10

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29 July 2017

Masaaki Oyama

11

1 reference

29 July 2017

language of work or name

English

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publication date

10 November 2010

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29 July 2017

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29 July 2017

volume

5

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29 July 2017

issue

11

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29 July 2017

page(s)

e13926

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Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

10 November 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

21 June 2018

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21 June 2018

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An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing glioblastoma cells

21 June 2018

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Signaling flux redistribution at toll-like receptor pathway junctions

21 June 2018

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Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

21 June 2018

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Bayesian learning of biological pathways on genomic data assimilation

21 June 2018

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Temporal perturbation of tyrosine phosphoproteome dynamics reveals the system-wide regulatory networks

21 June 2018

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Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS

21 June 2018

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A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R.

21 June 2018

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Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface

21 June 2018

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Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses

21 June 2018

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An Improved Procedure for EI Nino Forecasting: Implications for Predictability

21 June 2018

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The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity

21 June 2018

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Modeling and estimation of dynamic EGFR pathway by data assimilation approach using time series proteomic data.

21 June 2018

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Genomic data assimilation for estimating hybrid functional Petri net from time-course gene expression data.

21 June 2018

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Epidermal growth factor receptor mutations in lung cancer

21 June 2018

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Diversity of translation start sites may define increased complexity of the human short ORFeome

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

The EGF receptor family: spearheading a merger of signaling and therapeutics

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

AYUMS: an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction

21 June 2018

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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

21 June 2018

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Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Phosphoproteomic analysis of Her2/neu signaling and inhibition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Phosphotyrosine interactome of the ErbB-receptor kinase family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Modeling the effects of HER/ErbB1-3 coexpression on receptor dimerization and biological response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

A quantitative protein interaction network for the ErbB receptors using protein microarrays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

21 June 2018

Biological robustness

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Analysis of small human proteins reveals the translation of upstream open reading frames of mRNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Signaling in small subcellular volumes. II. Stochastic and diffusion effects on synaptic network properties

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

A novel proteomic screen for peptide-protein interactions

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Molecular Mechanism for a Role of SHP2 in Epidermal Growth Factor Receptor Signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

An integrated model of epidermal growth factor receptor trafficking and signal transduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

A carboxyl-terminal mutation of the epidermal growth factor receptor alters tyrosine kinase activity and substrate specificity as measured by a fluorescence polarization assay

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Cbl: many adaptations to regulate protein tyrosine kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Subsets of epidermal growth factor receptors during activation and endocytosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Tyrosine phosphorylation of ras GTPase-activating protein does not require association with the epidermal growth factor receptor.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

A network model of early events in epidermal growth factor receptor signaling that accounts for combinatorial complexity

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013926

A decompositional approach to parameter estimation in pathway modeling: a case study of the Akt and MAPK pathways and their crosstalk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013926

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013926

Parameter estimation of in silico biological pathways with particle filtering towards a petascale computing

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Constructing biological pathway models with hybrid functional Petri nets.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

A versatile petri net based architecture for modeling and simulation of complex biological processes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2978091

Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

30 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013926

Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013926

Prediction and validation of the distinct dynamics of transient and sustained ERK activation

21 January 2018

1 reference

12 December 2020

Modeling and simulation with Hybrid Functional Petri Nets of the role of interleukin-6 in human early haematopoiesis

1 reference

12 December 2020

Epidermal growth factor receptor internalization rate is regulated by negative charges near the SH2 binding site Tyr992

1 reference

12 December 2020

Hybrid Petri net representation of gene regulatory network

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0013926

Identifiers

DOI

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference