(Q33750727)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Louise E Olofsson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Alison S Reed

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Merisa L Piper

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Martin G Myers

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Allison W Xu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

0 references

publication date

12 January 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

894-906

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

16 January 2020

copyright license

start time

30 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2844837/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Leptin targets in the mouse brain

21 June 2018

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Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity

21 June 2018

1 reference

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Endoplasmic reticulum stress induces leptin resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight

21 June 2018

1 reference

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The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity.

21 June 2018

1 reference

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Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice

21 June 2018

1 reference

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Specific physiological roles for signal transducer and activator of transcription 3 in leptin receptor-expressing neurons

21 June 2018

1 reference

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Hypothalamic phosphatidylinositol 3-kinase pathway of leptin signaling is impaired during the development of diet-induced obesity in FVB/N mice

21 June 2018

1 reference

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Mechanisms of leptin action and leptin resistance

21 June 2018

1 reference

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Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

21 June 2018

1 reference

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Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease

21 June 2018

1 reference

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AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons

21 June 2018

1 reference

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Leptin receptor signaling and action in the central nervous system

21 June 2018

1 reference

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Hypothalamic mTOR signaling regulates food intake

21 June 2018

1 reference

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Effects of hypothalamic neurodegeneration on energy balance

21 June 2018

1 reference

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The role of insulin receptor substrate 2 in hypothalamic and beta cell function.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

PI3K integrates the action of insulin and leptin on hypothalamic neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Monogenic obesity in humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Region-specific leptin resistance within the hypothalamus of diet-induced obese mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Ageing increases SOCS-3 expression in rat hypothalamus: effects of food restriction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B.

21 June 2018

1 reference

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PTP1B regulates leptin signal transduction in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Selective deletion of leptin receptor in neurons leads to obesity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Down-regulated STAT3 messenger ribonucleic acid and STAT3 protein in the hypothalamic arcuate nucleus of the obese leptin-deficient (ob/ob) mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Generalized lacZ expression with the ROSA26 Cre reporter strain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Identification of SOCS-3 as a potential mediator of central leptin resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Endoplasmic reticulum stress plays a central role in development of leptin resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2844837

A key role of leptin in the control of regulatory T cell proliferation

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20068134

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential accessibility of circulating leptin to individual hypothalamic sites

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20068134

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB09-1024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20068134%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

20068134

1 reference