(Q33754475)

29 July 2017

title

Telomere length regulation and transcriptional silencing in KU80-deficient Trypanosoma brucei (English)

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29 July 2017

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Christian J Janzen

1

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29 July 2017

Fabian Lander

series ordinal

2

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29 July 2017

Oliver Dreesen

series ordinal

3

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29 July 2017

George A M Cross

series ordinal

4

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29 July 2017

language of work or name

English

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publication date

15 December 2004

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29 July 2017

published in

Nucleic Acids Research

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29 July 2017

volume

32

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29 July 2017

issue

22

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29 July 2017

page(s)

6575-6584

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A means to a DNA end: the many roles of Ku.

29 July 2017

cites work

1 reference

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Multiple pathways for telomere tethering: functional implications of subnuclear position for heterochromatin formation.

21 June 2018

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Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast

21 June 2018

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Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins.

21 June 2018

1 reference

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Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends

21 June 2018

1 reference

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Telomere maintenance and DNA replication: how closely are these two connected?

21 June 2018

1 reference

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Subnuclear localization of Ku protein: functional association with RNA polymerase II elongation sites.

21 June 2018

1 reference

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Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast.

21 June 2018

1 reference

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Transcriptional silencing at Saccharomyces telomeres: implications for other organisms

21 June 2018

1 reference

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Antigenic variation in trypanosomes: enhanced phenotypic variation in a eukaryotic parasite

21 June 2018

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Turning telomeres off and on.

21 June 2018

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Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.

21 June 2018

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t-loops at trypanosome telomeres.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Telomeres and their control

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Nuclear pore complexes in the organization of silent telomeric chromatin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

21 June 2018

1 reference

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A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Trypanosoma brucei variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Regulated processive transcription of chromatin by T7 RNA polymerase in Trypanosoma brucei.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Position-dependent and promoter-specific regulation of gene expression in Trypanosoma brucei.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Antigenic variation in trypanosomes: secrets surface slowly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

VSG gene expression site control in insect form Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Gene expression mediated by bacteriophage T3 and T7 RNA polymerases in transgenic trypanosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Differential size variations between transcriptionally active and inactive telomeres ofTrypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

An analysis of cosmid clones of nuclear DNA from Trypanosoma brucei shows that the genes for variant surface glycoproteins are clustered in the genome.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Antigenic variation in clones of animal-infective Trypanosoma brucei derived and maintained in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

The effect of citrate/cis-aconitate on oxidative metabolism during transformation of Trypanosoma brucei.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Human telomeres are attached to the nuclear matrix

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat ofTrypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=545459

Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei

10 December 2018

1 reference

12 December 2020

Nuclear localization of Ku antigen is promoted independently by basic motifs in the Ku70 and Ku80 subunits

1 reference

12 December 2020

Telomere shortening and cell cycle arrest in Trypanosoma brucei expressing human telomeric repeat factor TRF1

1 reference

12 December 2020

Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions

1 reference

12 December 2020

Est1p as a cell cycle-regulated activator of telomere-bound telomerase

1 reference

12 December 2020

Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast

1 reference

12 December 2020

Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase

1 reference

12 December 2020

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

12 December 2020

Growth of chromosome ends in multiplying trypanosomes

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKH991

1 reference

29 July 2017

1 reference

29 July 2017

1 reference