(Q33760369)

29 July 2017

1 reference

title

Serine proteinase inhibitor therapy in alpha(1)-antitrypsin inhibitor deficiency and cystic fibrosis (English)

1 reference

29 July 2017

0 references

Döring G

1

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29 July 2017

language of work or name

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1 November 1999

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29 July 2017

number of pages

13

1 reference

based on heuristic

inferred from page(s)

published in

Pediatric Pulmonology

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29 July 2017

volume

28

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29 July 2017

issue

5

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29 July 2017

page(s)

363-375

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Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy

29 July 2017

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21 January 2018

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Molecular basis, clinical consequences and diagnosis of alpha-1 antitrypsin deficiency

21 January 2018

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Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase

21 January 2018

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Alpha-1-antitrypsin deficiency: biochemistry and clinical manifestations

21 January 2018

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The proteinase-antiproteinase theory of emphysema: a speculative analysis of recent advances into the pathogenesis of emphysema

21 January 2018

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Inhibitory conformation of the reactive loop of alpha 1-antitrypsin

21 January 2018

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21 January 2018

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Lung polymers in Z alpha1-antitrypsin deficiency-related emphysema

21 January 2018

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Intermediate alpha 1-antitrypsin deficiency PiSZ: a risk factor for pulmonary emphysema?

21 January 2018

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Alpha1-antitrypsin deficiency alleles and the Taq-I G-->A allele in cystic fibrosis lung disease

21 January 2018

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Lower airway inflammation in infants and young children with cystic fibrosis.

21 January 2018

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The role of fibrin degradation products in neutrophil recruitment to the lung

21 January 2018

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Mucoid Pseudomonas aeruginosa resists nonopsonic phagocytosis by human neutrophils and macrophages

21 January 2018

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21 January 2018

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Anaerobic production of alginate by Pseudomonas aeruginosa: alginate restricts diffusion of oxygen

21 January 2018

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Reduction of ciliary beat frequency in vitro by sputum from patients with bronchiectasis: a serine proteinase effect

21 January 2018

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Proteins of the cystic fibrosis respiratory tract. Fragmented immunoglobulin G opsonic antibody causing defective opsonophagocytosis

21 January 2018

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Proteolytic inactivation of dog lung surfactant-associated proteins by neutrophil elastase

21 January 2018

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Complement receptor expression on neutrophils at an inflammatory site, the Pseudomonas-infected lung in cystic fibrosis

21 January 2018

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Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch

21 January 2018

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Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells

21 January 2018

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Cystic fibrosis sputum induces a secretory response from airway gland serous cells that can be prevented by neutrophil protease inhibitors

21 January 2018

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Matrix metalloproteases and lung disease

21 January 2018

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Collagenase is a component of the specific granules of human neutrophil leucocytes

21 January 2018

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21 January 2018

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Collagenase in the Lower Respiratory Tract of Patients with Idiopathic Pulmonary Fibrosis

21 January 2018

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Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema.

21 January 2018

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Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development

21 January 2018

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Regulation of the serine proteinase inhibitor (SERPIN) gene alpha 1-antitrypsin: a paradigm for other SERPINs

21 January 2018

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Human plasma proteinase inhibitors

21 January 2018

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Kinetic mechanism of the inhibition of cathepsin G by alpha 1-antichymotrypsin and alpha 1-proteinase inhibitor

21 January 2018

1 reference

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Biosynthesis of alpha1-proteinase inhibitor by human lung-derived epithelial cells

21 January 2018

1 reference

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Stimulatory effect of inflammatory cytokines on alpha 1-antichymotrypsin expression in human lung-derived epithelial cells

21 January 2018

1 reference

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Pseudomonas aeruginosa lipopolysaccharide induces CF-like alteration of protein secretion by human tracheal gland cells

21 January 2018

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Production of recombinant human monocyte/neutrophil elastase inhibitor (rM/NEI).

21 January 2018

1 reference

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Use of a highly purified alpha 1-antitrypsin standard to establish ranges for the common normal and deficient alpha 1-antitrypsin phenotypes

21 January 2018

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Inactivation of alpha1-proteinase inhibitor as a broad screen for detecting proteolytic activities in unknown samples

21 January 2018

1 reference

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Rapid inactivation of alpha1-protease inhibitor (alpha1-antitrypsin) by elastase

21 January 2018

1 reference

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Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils

21 January 2018

1 reference

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Interstitial collagenase (matrix metalloproteinase-1) expresses serpinase activity

21 January 2018

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Substrate specificities and activation mechanisms of matrix metalloproteinases

21 January 2018

1 reference

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Preferential inactivation of tissue inhibitor of metalloproteinases-1 that is bound to the precursor of matrix metalloproteinase 9 (progelatinase B) by human neutrophil elastase.

21 January 2018

1 reference

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Tissue destruction by neutrophils

21 January 2018

1 reference

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Enzymatic inactivation of human alpha-1-proteinase inhibitor by neutrophil myeloperoxidase

21 January 2018

1 reference

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Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils

21 January 2018

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Increased levels of elastase and alpha1-antitrypsin in sputum of asthmatic patients.

21 January 2018

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Risk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase

21 January 2018

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Elastolytic activity in pulmonary lavage fluid from patients with adult respiratory-distress syndrome

21 January 2018

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Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor

21 January 2018

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Synthesis in E. coli of alpha 1-antitrypsin variants of therapeutic potential for emphysema and thrombosis.

21 January 2018

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Synthesis in yeast of a functional oxidation-resistant mutant of human alpha-antitrypsin.

21 January 2018

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The intrapulmonary half-life and safety of aerosolized alpha1-protease inhibitor in normal volunteers.

21 January 2018

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Replacement therapy of alpha 1-antitrypsin deficiency. Reversal of protease-antiprotease imbalance within the alveolar structures of PiZ subjects

21 January 2018

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Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema

21 January 2018

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Does alpha1-antitrypsin augmentation therapy slow the annual decline in FEV1 in patients with severe hereditary alpha1-antitrypsin deficiency? Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen (WATL) alpha1-AT study group.

21 January 2018

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Pulmonary deposition and clearance of aerosolized alpha-1-proteinase inhibitor administered to dogs and to sheep

21 January 2018

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Recombinant DNA-produced alpha 1-antitrypsin administered by aerosol augments lower respiratory tract antineutrophil elastase defenses in individuals with alpha 1-antitrypsin deficiency

21 January 2018

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Aerosols for therapy and diagnosis

21 January 2018

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Regional variability of lung inflammation in cystic fibrosis.

21 January 2018

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Gene therapy approaches for inherited and acquired lung diseases

21 January 2018

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Plasmid-liposome transfer of the alpha 1 antitrypsin gene to cystic fibrosis bronchial epithelial cells prevents elastase-induced cell detachment and cytokine release

21 January 2018

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Clonal gene therapy: transplanted mouse fibroblast clones express human alpha 1-antitrypsin gene in vivo

21 January 2018

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Aerosol and intravenous transfection of human alpha 1-antitrypsin gene to lungs of rabbits

21 January 2018

1 reference

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Adenovirus-mediated in vivo gene transfer and expression in normal rat liver

21 January 2018

1 reference

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Gene expression following direct injection of DNA into liver

21 January 2018

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Hepatic gene therapy: persistent expression of human alpha 1-antitrypsin in mice after direct gene delivery in vivo

21 January 2018

1 reference

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Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo

21 January 2018

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Adenovirus-mediated expression of an elastase-specific inhibitor (elafin): a comparison of different promoters

21 January 2018

1 reference

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Human neutrophil elastase releases cell surface mucins from primary cultures of hamster tracheal epithelial cells

21 January 2018

1 reference

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An ultrastructural study of the response of hamster bronchial epithelium to human neutrophil elastase

21 January 2018

1 reference

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Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release. Role of surface proteinase-3, alpha1-antitrypsin, and Fcgamma receptors

21 January 2018

1 reference

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Alpha-1 antitrypsin up-regulates human B cell differentiation selectively into IgE- and IgG4- secreting cells

21 January 2018

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Pitfalls in antiprotease therapy of emphysema

21 January 2018

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10.1002/(SICI)1099-0496(199911)28:5<363::AID-PPUL9>3.0.CO;2-#

21 January 2018

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DOI

1 reference

29 July 2017

1 reference