(Q33762335)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Enhancing the efficiency and regioselectivity of P450 oxidation catalysts by unnatural amino acid mutagenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

Joshua N Kolev

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Jacqueline M Zaengle

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Rajesh Ravikumar

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

publication date

1 April 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

1001-1010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

Discovery of potent parthenolide-based antileukemic agents enabled by late-stage P450-mediated C-H functionalization

12 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Controlled oxidation of remote sp3 C-H bonds in artemisinin via P450 catalysts with fine-tuned regio- and stereoselectivity

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Catalytic, mild, and selective oxyfunctionalization of linear alkanes: current challenges

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Diversity of P450 enzymes in the biosynthesis of natural products

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Active site substitution A82W improves the regioselectivity of steroid hydroxylation by cytochrome P450 BM3 mutants as rationalized by spin relaxation nuclear magnetic resonance studies.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Innate and Guided C–H Functionalization Logic

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

P450(BM3) (CYP102A1): connecting the dots.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

If C-H bonds could talk: selective C-H bond oxidation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Microbial transformation of (+)-nootkatone and the antiproliferative activity of its metabolites

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Combinatorial alanine substitution enables rapid optimization of cytochrome P450BM3 for selective hydroxylation of large substrates

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Screening of a minimal enriched P450 BM3 mutant library for hydroxylation of cyclic and acyclic alkanes

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Residue-specific incorporation of non-canonical amino acids into proteins: recent developments and applications

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Adding new chemistries to the genetic code

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

P450 enzymes: their structure, reactivity, and selectivity-modeled by QM/MM calculations

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Hydrocarbon hydroxylation by cytochrome P450 enzymes

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Efforts toward the direct experimental characterization of enzyme microenvironments: tyrosine100 in dihydrofolate reductase

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Chemo-enzymatic fluorination of unactivated organic compounds

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Evolutionary history of a specialized p450 propane monooxygenase

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Site-specific incorporation of a (19)F-amino acid into proteins as an NMR probe for characterizing protein structure and reactivity.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Improving nature's enzyme active site with genetically encoded unnatural amino acids

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Enantioselective alpha-hydroxylation of 2-arylacetic acid derivatives and buspirone catalyzed by engineered cytochrome P450 BM-3.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Structure and chemistry of cytochrome P450.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

A genetically encoded photocaged amino acid

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Global incorporation of norleucine in place of methionine in cytochrome P450 BM-3 heme domain increases peroxygenase activity

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Addition of the keto functional group to the genetic code of Escherichia coli.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

P450 BM3: the very model of a modern flavocytochrome

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Adding L-3-(2-Naphthyl)alanine to the genetic code of E. coli

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Role of Thr-252 in cytochrome P450cam: a study with unnatural amino acid mutagenesis

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Controlling site selectivity in palladium-catalyzed C-H bond functionalization

22 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

The heme monooxygenase cytochrome P450cam can be engineered to oxidize ethane to ethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

Engineered alkane-hydroxylating cytochrome P450(BM3) exhibiting nativelike catalytic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

Engineering and improvement of the efficiency of a chimeric [P450cam-RhFRed reductase domain] enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

Tuning P450 Enzymes as Oxidation Catalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

Site-specific insertion of 3-aminotyrosine into subunit alpha2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

A genetically encoded photocaged tyrosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

Improving a natural enzyme activity through incorporation of unnatural amino acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

An efficient system for the evolution of aminoacyl-tRNA synthetase specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

Enhancing the utility of unnatural amino acid synthetases by manipulating broad substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Further improvement of phosphite dehydrogenase thermostability by saturation mutagenesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

On the relationship between the metabolic and thermodynamic stabilities of T4 lysozymes. Measurements in Escherichia coli.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059402

Identification of Critical Residues in Novel Drug Metabolizing Mutants of Cytochrome P450 BM3 Using Random Mutagenesis

30 October 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.201400060

The structural stability of a protein is an important determinant of its proteolytic susceptibility in Escherichia coli

21 January 2018

1 reference

12 December 2020

Diverse organo-peptide macrocycles via a fast and catalyst-free oxime/intein-mediated dual ligation

1 reference

12 December 2020

Uncoupling oxygen transfer and electron transfer in the oxygenation of camphor analogues by cytochrome P450-CAM. Direct observation of an intermolecular isotope effect for substrate C-H activation

1 reference

12 December 2020

Is protein turnover thermodynamically controlled?

1 reference

12 December 2020

A regioselective biocatalyst for alkane activation under mild conditions

1 reference

12 December 2020

Identification and characterization of two functional domains in cytochrome P-450BM-3, a catalytically self-sufficient monooxygenase induced by barbiturates in Bacillus megaterium

1 reference

12 December 2020

P450 fingerprinting method for rapid discovery of terpene hydroxylating P450 catalysts with diversified regioselectivity

1 reference

12 December 2020

Identifiers

DOI

10.1002/CBIC.201400060

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24692265

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24692265%20AND%20SRC:MED&resulttype=core&format=json