(Q33765052)

29 July 2017

title

β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway (English)

1 reference

29 July 2017

4

Gi-Young Kim

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29 July 2017

5

Wun-Jae Kim

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29 July 2017

Hai Yang Yu

1

1 reference

29 July 2017

Sung Ok Kim

2

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29 July 2017

Cheng-Yun Jin

3

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29 July 2017

Young Hyun Yoo

6

1 reference

29 July 2017

Yung Hyun Choi

7

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29 July 2017

publication date

1 May 2014

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Biomolecules & therapeutics

29 July 2017

published in

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29 July 2017

volume

22

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29 July 2017

issue

3

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29 July 2017

page(s)

184-192

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Creative Commons Attribution-NonCommercial 3.0 Unported

29 July 2017

copyright license

start time

31 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Beta-lapachone (LAPA) decreases cell viability and telomerase activity in leukemia cells: suppression of telomerase activity by LAPA

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Induction of Egr-1 is associated with anti-metastatic and anti-invasive ability of beta-lapachone in human hepatocarcinoma cells

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Beta-lapachone, a quinone isolated from Tabebuia avellanedae, induces apoptosis in HepG2 hepatoma cell line through induction of Bax and activation of caspase

22 June 2018

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Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma

22 June 2018

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beta-lapachone induces growth inhibition and apoptosis in bladder cancer cells by modulation of Bcl-2 family and activation of caspases

22 June 2018

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Down-regulation of cyclooxygenase-2 and telomerase activity by beta-lapachone in human prostate carcinoma cells

22 June 2018

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Growth inhibition of A549 human lung carcinoma cells by beta-lapachone through induction of apoptosis and inhibition of telomerase activity.

22 June 2018

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22 June 2018

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22 June 2018

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Suppression of Human Prostate Cancer Cell Growth by β-Lapachone via Down-regulation of pRB Phosphorylation and Induction of Cdk Inhibitor p21WAF1/CIP1

22 June 2018

1 reference

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Apoptosis: biochemical aspects and clinical implications

22 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060078

Caspase-8-mediated BID cleavage and release of mitochondrial cytochrome c during Nomega-hydroxy-L-arginine-induced apoptosis in MDA-MB-468 cells. Antagonistic effects of L-ornithine

22 June 2018

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Mitochondrial control of cell death

22 June 2018

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Potential antipsoriatic agents: lapacho compounds as potent inhibitors of HaCaT cell growth

22 June 2018

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Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones.

22 June 2018

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Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

22 June 2018

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beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin

22 June 2018

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Inhibition of potentially lethal DNA damage repair in human tumor cells by beta-lapachone, an activator of topoisomerase I.

22 June 2018

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beta-Lapachone, an inhibitor of oncornavirus reverse transcriptase and eukaryotic DNA polymerase-alpha. Inhibitory effect, thiol dependence and specificity

22 June 2018

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Anti-inflammatory and anti-arthritic activities of 3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (β-lapachone).

22 June 2018

1 reference

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An in vivo analysis of MMC-induced DNA damage and its repair

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060078

β-Lapachone Reduces Endotoxin-induced Macrophage Activation and Lung Edema and Mortality

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060078

beta-lapachone, a novel plant product, overcomes drug resistance in human multiple myeloma cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060078

Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060078

Antibacterial and antifungal compounds from Kigelia pinnata

30 October 2018

1 reference

12 December 2020

Activation of c-Jun NH2-terminal kinase and subsequent CPP32/Yama during topoisomerase inhibitor beta-lapachone-induced apoptosis through an oxidation-dependent pathway

1 reference

12 December 2020

Phosphorylation of p53, induction of Bax and activation of caspases during beta-lapachone-mediated apoptosis in human prostate epithelial cells

1 reference

12 December 2020

Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives-eleutherin, alpha lapachone, and beta lapachone

1 reference

12 December 2020

Upregulated Akt signaling adjacent to gastric cancers: implications for screening and chemoprevention

1 reference

12 December 2020

10.4062/BIOMOLTHER.2014.026

Identifiers

DOI

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29 July 2017

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29 July 2017

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