(Q33768940)

29 July 2017

1 reference

30 January 2021

1 reference

title

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles (English)

1 reference

phospholipase A2 inhibitors

29 July 2017

1 reference

17 June 2019

1 reference

7 November 2019

1 reference

7 November 2019

1 reference

13 November 2020

1 reference

30 January 2021

15

1 reference

29 July 2017

34

1 reference

29 July 2017

Martina Müller-Nurasyid

42

Martina Müller-Nurasyid

0 references

Heribert Schunkert

56

Heribert Schunkert

0 references

Eric Boerwinkle

47

Eric Boerwinkle

0 references

Mathias Gorski

25

Mathias Gorski

0 references

Børge G. Nordestgaard

60

Børge G Nordestgaard

0 references

Satu Männistö

21

Satu Männistö

1 reference

29 July 2017

Jukka Kontto

16

0 references

Adam S. Butterworth

Adam S Butterworth

64

0 references

Giovanni Veronesi

Giovanni Veronesi

19

0 references

Stephen Burgess

Stephen Burgess

6

0 references

Honghuang Lin

Honghuang Lin

23

0 references

Philippe Amouyel

Philippe Amouyel

45

0 references

Markus Perola

17

Markus Perola

1 reference

29 July 2017

46

Veikko Salomaa

1 reference

29 July 2017

Anders Malarstig

33

0 references

Nilesh Samani

57

Nilesh J Samani

1 reference

29 July 2017

61

Danish Saleheen

1 reference

29 July 2017

51

Naveed Sattar

1 reference

29 July 2017

13

Stella Trompet

1 reference

29 July 2017

58

Sekar Kathiresan

1 reference

29 July 2017

55

Panos Deloukas

1 reference

29 July 2017

28

Patricia B Munroe

1 reference

29 July 2017

18

Stefan Blankenberg

1 reference

29 July 2017

50

J Wouter Jukema

1 reference

29 July 2017

65

John Danesh

1 reference

29 July 2017

8

Pei Gao

1 reference

29 July 2017

54

Dewan S Alam

1 reference

29 July 2017

11

Sune F Nielsen

1 reference

29 July 2017

62

Joanna Mm Howson

1 reference

29 July 2017

29

Georg B Ehret

1 reference

29 July 2017

41

Frank Kee

1 reference

29 July 2017

44

Dominique Arveiler

1 reference

29 July 2017

43

Jean Ferrières

1 reference

29 July 2017

3

Praveen Surendran

1 reference

29 July 2017

Emanuele Di Angelantonio

63

Emanuele Di Angelantonio

1 reference

29 July 2017

5

Rajiv Chowdhury

1 reference

29 July 2017

4

Nathan O Stitziel

1 reference

29 July 2017

2

Daniel F Freitag

1 reference

29 July 2017

9

James R Staley

1 reference

29 July 2017

12

Muriel Caslake

1 reference

29 July 2017

26

Vladan Mijatovic

1 reference

29 July 2017

32

Maria Uria-Nickelsen

1 reference

Abdulla Al Shafi Majumder

29 July 2017

53

Abdulla Al Shafi Majumder

1 reference

29 July 2017

7

Stephen Kaptoge

1 reference

29 July 2017

20

Francesco Gianfagna

1 reference

29 July 2017

49

Ian Ford

1 reference

29 July 2017

John M Gregson

1

1 reference

29 July 2017

Peter Willeit

10

1 reference

29 July 2017

Linda M Polfus

14

1 reference

29 July 2017

Akinori Kimura

22

1 reference

29 July 2017

Dermot F Reilly

24

1 reference

29 July 2017

CKDGen consortium

27

1 reference

29 July 2017

International Consortium for Blood Pressure

30

1 reference

29 July 2017

Alex Thompson

31

1 reference

29 July 2017

CHARGE inflammation working group

35

1 reference

29 July 2017

Thomas F Vogt

36

1 reference

29 July 2017

Taishi Sasaoka

37

1 reference

29 July 2017

Fumihiko Takeuchi

38

1 reference

29 July 2017

Norihiro Kato

39

1 reference

29 July 2017

Yoshiji Yamada

40

1 reference

29 July 2017

Simon G Thompson

48

1 reference

29 July 2017

Chris J Packard

52

1 reference

29 July 2017

MICAD Exome consortium

59

1 reference

29 July 2017

EPIC-CVD consortium and the CHD Exome+ consortium

66

1 reference

29 July 2017

publication date

11 December 2016

1 reference

European Journal of Preventive Cardiology

29 July 2017

1 March 2017

9 references

14 March 2019

19 March 2019

22 March 2019

17 June 2019

25 June 2019

2 October 2019

7 November 2019

13 November 2020

30 January 2021

10 references

29 July 2017

14 March 2019

19 March 2019

22 March 2019

17 June 2019

25 June 2019

2 October 2019

7 November 2019

13 November 2020

30 January 2021

24

1 reference

29 July 2017

issue

5

1 reference

29 July 2017

page(s)

492-504

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

copyright license

9 references

14 March 2019

19 March 2019

22 March 2019

17 June 2019

25 June 2019

2 October 2019

7 November 2019

13 November 2020

on focus list of Wikimedia project

30 January 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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The Bangladesh Risk of Acute Vascular Events (BRAVE) Study: objectives and design

28 July 2018

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Coronary heart disease and genetic variants with low phospholipase A2 activity

28 July 2018

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Inactivating mutations in NPC1L1 and protection from coronary heart disease

28 July 2018

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28 July 2018

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Effect of darapladib on major coronary events after an acute coronary syndrome: the SOLID-TIMI 52 randomized clinical trial

28 July 2018

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Inflammation modulation and cardiovascular disease prevention.

28 July 2018

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Efficient multivariate linear mixed model algorithms for genome-wide association studies

28 July 2018

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Discovery and refinement of loci associated with lipid levels

28 July 2018

1 reference

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Validating therapeutic targets through human genetics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

28 July 2018

1 reference

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An integrated map of genetic variation from 1,092 human genomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

Evolution and functional impact of rare coding variation from deep sequencing of human exomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

Genome-wide association and functional follow-up reveals new loci for kidney function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

28 July 2018

1 reference

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Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

28 July 2018

1 reference

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Darapladib: an emerging therapy for atherosclerosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry

28 July 2018

1 reference

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Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

28 July 2018

1 reference

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

28 July 2018

1 reference

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Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque

28 July 2018

1 reference

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The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, dou

28 July 2018

1 reference

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Case-cohort design in practice - experiences from the MORGAM Project

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

The mammalian unfolded protein response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5460752

Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target

28 July 2018

1 reference

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MORGAM (an international pooling of cardiovascular cohorts).

28 July 2018

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The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma

28 July 2018

1 reference

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Loss of activity of plasma platelet-activating factor acetylhydrolase due to a novel Gln281-->Arg mutation

28 July 2018

1 reference

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Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase

28 July 2018

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Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

28 July 2018

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Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males

28 July 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

Darapladib for Preventing Ischemic Events in Stable Coronary Heart Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

Analysis of protein-coding genetic variation in 60,706 humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

Plasma Platelet-activating Factor Acetylhydrolase Is a Secreted Phospholipase A2 with a Catalytic Triad

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

Genetically elevated lipoprotein(a) and increased risk of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries.

21 January 2018

1 reference

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The Pakistan Risk of Myocardial Infarction Study: a resource for the study of genetic, lifestyle and other determinants of myocardial infarction in South Asia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

Instrumental Variable Estimation of Causal Risk Ratios and Causal Odds Ratios in Mendelian Randomization Analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

Human genetics as a foundation for innovative drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

The support of human genetic evidence for approved drug indications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F2047487316682186

Effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity in Japanese dyslipidemic patients, with exploratory analysis of a PLA2G7 gene polymorphism of Val279Phe

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27940953

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age, and atherosclerosis in a Japanese population

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27940953

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1177/2047487316682186

1 reference

29 July 2017

1 reference

29 July 2017

1 reference