(Q33769993)

English

Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissue (English)

1 reference

Europe PubMed Central

29 July 2017

1 reference

based on heuristic

inferred from title

Tomáš Cihlář

4

object named as

Tomas Cihlar

1 reference

Europe PubMed Central

29 July 2017

author name string

William A Lee

1

1 reference

Europe PubMed Central

29 July 2017

Gong-Xin He

2

1 reference

Europe PubMed Central

29 July 2017

Eugene Eisenberg

3

1 reference

Europe PubMed Central

29 July 2017

Swami Swaminathan

5

1 reference

Europe PubMed Central

29 July 2017

Andrew Mulato

6

1 reference

Europe PubMed Central

29 July 2017

Kenneth C Cundy

7

1 reference

Europe PubMed Central

29 July 2017

language of work or name

0 references

publication date

1 May 2005

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Europe PubMed Central

29 July 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

29 July 2017

49

1 reference

Europe PubMed Central

29 July 2017

5

1 reference

Europe PubMed Central

29 July 2017

1898-1906

1 reference

Europe PubMed Central

29 July 2017

Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication

1 reference

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Metabolism of GS-7340, a novel phenyl monophosphoramidate intracellular prodrug of PMPA, in blood

1 reference

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A simple relationship between viral load and survival time in HIV-1 infection

1 reference

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4 July 2018

Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine

1 reference

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Use of real-time PCR and molecular beacons to detect virus replication in human immunodeficiency virus type 1-infected individuals on prolonged effective antiretroviral therapy

1 reference

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4 July 2018

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

1 reference

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The presence of substituents on the aryl moiety of the aryl phosphoramidate derivative of d4T enhances anti-HIV efficacy in cell culture: A structure-activity relationship.

1 reference

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Human immunodeficiency virus type 1 in the semen of men receiving highly active antiretroviral therapy

1 reference

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4 July 2018

Drug concentration heterogeneity facilitates the evolution of drug resistance.

1 reference

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4 July 2018

Safety, pharmacokinetics, and antiretroviral activity of intravenous 9-[2-(R)-(Phosphonomethoxy)propyl]adenine, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults.

1 reference

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4 July 2018

Pharmacokinetics and bioavailability of the anti-human immunodeficiency virus nucleotide analog 9-[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) in dogs.

1 reference

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4 July 2018

Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA

1 reference

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A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team

1 reference

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4 July 2018

The implications of drug resistance for strategies of combination antiviral chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

4 July 2018

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

4 July 2018

Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

4 July 2018

Metabolism and in vitro antiretroviral activities of bis(pivaloyloxymethyl) prodrugs of acyclic nucleoside phosphonates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

4 July 2018

Synthesis, oral bioavailability determination, and in vitro evaluation of prodrugs of the antiviral agent 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

4 July 2018

Cell volumes of normal and malignant mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

4 July 2018

Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents

1 reference

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4 July 2018

New soluble-formazan assay for HIV-1 cytopathic effects: application to high-flux screening of synthetic and natural products for AIDS-antiviral activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

4 July 2018

Tenofovir disoproxil fumarate in nucleoside-resistant HIV-1 infection: a randomized trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

30 October 2018

Visualizing the generation of memory CD4 T cells in the whole body

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

30 October 2018

The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

30 October 2018

Ongoing HIV dissemination during HAART.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

30 October 2018

Probing the mechanism of action and decomposition of amino acid phosphomonoester amidates of antiviral nucleoside prodrugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

30 October 2018

Persistence of HIV-1 Transcription in Peripheral-Blood Mononuclear Cells in Patients Receiving Potent Antiretroviral Therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1087627

30 October 2018

Decay of cell-associated HIV-1 DNA correlates with residual replication in patients treated during acute HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15855512

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The measurement of lymphocyte volume: importance of reference particle deformability and counting solution tonicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15855512

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An improved method for the quantitative determination of deoxyribonucleoside triphosphates in cell extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15855512

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acyclic adenine nucleoside phosphonates in plasma determined by high-performance liquid chromatography with fluorescence detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15855512

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/15855512

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.49.5.1898-1906.2005

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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