(Q33770896)

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Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth

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Europe PubMed Central

PubMed publication ID

29 July 2017

Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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author name string

Swei Sunny Hann

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Qing Tang

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Fang Zheng

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Shunyu Zhao

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Jianping Chen

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ZhiYu Wang

6

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Europe PubMed Central

PubMed publication ID

29 July 2017

publication date

13 June 2014

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Europe PubMed Central

PubMed publication ID

29 July 2017

Molecular Cancer

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Europe PubMed Central

PubMed publication ID

29 July 2017

13

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Europe PubMed Central

PubMed publication ID

29 July 2017

149

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Europe PubMed Central

PubMed publication ID

29 July 2017

https://scigraph.springernature.com/pub.10.1186/1476-4598-13-149

0 references

Targeting 3-phosphoinositide-dependent protein kinase 1 by N-acetyl-cysteine through activation of peroxisome proliferators activated receptor alpha in human lung cancer cells, the role of p53 and p65.

1 reference

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AMPK: a contextual oncogene or tumor suppressor?

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Cancer statistics, 2013

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Combined treatment with peroxisome proliferator-activated receptor (PPAR) gamma ligands and gamma radiation induces apoptosis by PPARγ-independent up-regulation of reactive oxygen species-induced deoxyribonucleic acid damage signals in non-small cel

1 reference

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Peroxisome proliferator-activated receptor γ agonists induce cell cycle arrest through transcriptional regulation of Kruppel-like factor 4 (KLF4)

1 reference

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COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells

1 reference

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Prevention of JNK phosphorylation as a mechanism for rosiglitazone in neuroprotection after transient cerebral ischemia: activation of dual specificity phosphatase

1 reference

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4 July 2018

3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner

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β-Catenin loss in hepatocytes promotes hepatocellular cancer after diethylnitrosamine and phenobarbital administration to mice

1 reference

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PPARγ agonists regulate the expression of stemness and differentiation genes in brain tumour stem cells

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The antidiabetic drug ciglitazone induces high grade bladder cancer cells apoptosis through the up-regulation of TRAIL

1 reference

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Role of JNK in mammary gland development and breast cancer

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Induction of IGF-1R expression by EGR-1 facilitates the growth of prostate cancer cells

1 reference

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Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

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Targeting PDK1 in cancer

1 reference

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PAR1 plays a role in epithelial malignancies: transcriptional regulation and novel signaling pathway

1 reference

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4 July 2018

EGR1 expression: a calcium and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12,14-prostaglandin J2 and thiazolidinediones in breast cancer cells

1 reference

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Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner

1 reference

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

1 reference

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4 July 2018

Combined treatment with the Cox-2 inhibitor niflumic acid and PPARγ ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061523

4 July 2018

The PPARγ ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061523

4 July 2018

Rosiglitazone inhibits monocyte/macrophage adhesion through de novo adiponectin production in human monocytes.

1 reference

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4 July 2018

Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells

1 reference

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Peroxisome proliferator-activated receptor gamma activation inhibits progesterone-stimulated human MUC1 expression

1 reference

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4 July 2018

3-phosphoinositide-dependent protein kinase-1 regulates proliferation and survival of cancer cells with an activated mitogen-activated protein kinase pathway

1 reference

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Targeted therapies for non-small cell lung cancer

1 reference

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Down-regulation of 3-phosphoinositide-dependent protein kinase-1 levels inhibits migration and experimental metastasis of human breast cancer cells

1 reference

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Prostaglandin E2 stimulates human lung carcinoma cell growth through induction of integrin-linked kinase: the involvement of EP4 and Sp1.

1 reference

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Small-molecule inhibitors of PDK1.

1 reference

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Green tea catechin (-)-epicatechin gallate induces tumour suppressor protein ATF3 via EGR-1 activation

1 reference

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Egr-1 abrogates the E2F-1 block in terminal myeloid differentiation and suppresses leukemia

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Activation of peroxisome proliferator-activated receptor gamma contributes to the survival of T lymphoma cells by affecting cellular metabolism.

1 reference

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Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rosiglitazone protects against palmitate-induced pancreatic beta-cell death by activation of autophagy via 5'-AMP-activated protein kinase modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24925061

12 December 2020

based on heuristic

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10.1186/1476-4598-13-149

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Europe PubMed Central

PubMed publication ID

29 July 2017

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

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Europe PubMed Central

PubMed publication ID

29 July 2017

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