(Q33772507)

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Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692636%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692636%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

2

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5 February 2020

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Bernard A Fox

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5 February 2020

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Ulf Petrausch

1

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5 February 2020

Christopher Twitty

3

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5 February 2020

Christian H Poehlein

4

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5 February 2020

Daniel P Haley

5

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5 February 2020

Edwin B Walker

6

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5 February 2020

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publication date

19 August 2009

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5 February 2020

number of pages

8

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Journal of Immunology

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5 February 2020

183

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692636%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692636%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

3682-3689

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692636%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma

1 reference

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Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma

1 reference

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4 July 2018

The critical contribution of TGF-beta to the induction of Foxp3 expression and regulatory T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

1 reference

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4 July 2018

Transforming growth factor-beta and the immune response: implications for anticancer therapy

1 reference

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4 July 2018

Adjuvant therapeutic vaccination in patients with non-small cell lung cancer made lymphopenic and reconstituted with autologous PBMC: first clinical experience and evidence of an immune response

1 reference

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Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: from preclinical to phase I/II studies

1 reference

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4 July 2018

TGFbeta signalling in control of T-cell-mediated self-reactivity

1 reference

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4 July 2018

Tregs and rethinking cancer immunotherapy

1 reference

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4 July 2018

Regulatory T cells and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumour immunity

1 reference

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Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

1 reference

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4 July 2018

Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Immune resistance orchestrated by the tumor microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Th17: an effector CD4 T cell lineage with regulatory T cell ties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

In vivo instruction of suppressor commitment in naive T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Cancer vaccines: between the idea and the reality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Anti-tumor T cell response and protective immunity in mice that received sublethal irradiation and immune reconstitution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Natural versus adaptive regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

1 reference

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4 July 2018

A subset of metastatic human colon cancers expresses elevated levels of transforming growth factor beta1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Immunocytochemical localization of secreted transforming growth factor-beta 1 to the advancing edges of primary tumors and to lymph node metastases of human mammary carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-beta activities.

1 reference

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1 reference

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4 July 2018

The concept of immunological surveillance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

4 July 2018

IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

30 October 2018

Phase I clinical trial of a TGF-beta antisense-modified tumor cell vaccine in patients with advanced glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

30 October 2018

Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

30 October 2018

Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

30 October 2018

The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

30 October 2018

Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system.

1 reference

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30 October 2018

Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

30 October 2018

Development of antitumor immune responses in reconstituted lymphopenic hosts.

1 reference

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30 October 2018

A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850273

30 October 2018

Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression.

1 reference

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30 October 2018

Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival

1 reference

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30 October 2018

Transforming growth factor beta1 in ductal carcinoma in situ and invasive carcinomas of the breast

1 reference

https://pubmed.ncbi.nlm.nih.gov/19692636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic efficacy of T cells derived from lymph nodes draining a poorly immunogenic tumor transduced to secrete granulocyte-macrophage colony-stimulating factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/19692636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated serum levels of transforming growth factor-beta1 in patients with colorectal carcinoma: its association with tumor progression and its significant decrease after curative surgical resection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19692636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducing and expanding regulatory T cell populations by foreign antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/19692636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of belagenpumatucel-L, a transforming growth factor beta-2 antisense gene-modified allogeneic tumor cell vaccine in non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19692636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19692636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19692636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD28, TNF receptor, and IL-12 are critical for CD4-independent cross-priming of therapeutic antitumor CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19692636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.0900560

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692636%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692636%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692636%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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