(Q33774353)

29 July 2017

Targeting mTORC2 inhibits colon cancer cell proliferation in vitro and tumor formation in vivo (English)

1 reference

29 July 2017

1 reference

5

Olivier Dormond

1 reference

29 July 2017

Didier Roulin

1

1 reference

29 July 2017

Yannick Cerantola

series ordinal

2

1 reference

29 July 2017

Anne Dormond-Meuwly

series ordinal

3

1 reference

29 July 2017

Nicolas Demartines

series ordinal

4

1 reference

29 July 2017

12 March 2010

1 reference

29 July 2017

1 reference

29 July 2017

9

1 reference

29 July 2017

57

1 reference

https://scigraph.springernature.com/pub.10.1186/1476-4598-9-57

29 July 2017

0 references

cites work

Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

mTORC2 activity is elevated in gliomas and promotes growth and cell motility via overexpression of rictor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

Defining the role of mTOR in cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

Current development of mTOR inhibitors as anticancer agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

TOR signaling in growth and metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

mTOR signaling pathway is a target for the treatment of colorectal cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

Upstream and downstream of mTOR

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850884

30 October 2018

Identifiers

DOI

10.1186/1476-4598-9-57

1 reference

Dimensions Publication ID

29 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1476-4598-9-57

9 September 2019

1 reference

29 July 2017

1 reference