(Q33776739)

29 July 2017

title

Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system (English)

1 reference

29 July 2017

Josée Coulombe

1

1 reference

29 July 2017

Prasanna Gamage

2

1 reference

29 July 2017

Madison T Gray

3

1 reference

29 July 2017

Mei Zhang

4

1 reference

29 July 2017

Matthew Y Tang

5

1 reference

29 July 2017

John Woulfe

6

1 reference

29 July 2017

M Jill Saffrey

7

1 reference

29 July 2017

Douglas A Gray

8

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29 July 2017

publication date

19 June 2014

1 reference

Frontiers in Aging Neuroscience

29 July 2017

published in

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29 July 2017

volume

6

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29 July 2017

page(s)

129

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Cellular changes in the enteric nervous system during ageing

29 July 2017

cites work

1 reference

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Myenteric neuron numbers are maintained in aging mouse distal colon

28 July 2018

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Effects of oxaliplatin on mouse myenteric neurons and colonic motility

28 July 2018

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Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury.

28 July 2018

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Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut.

28 July 2018

1 reference

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Structures and folding pathways of topologically knotted proteins

28 July 2018

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Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons

28 July 2018

1 reference

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Degradation of ubiquitin: the fate of the cellular reaper

28 July 2018

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Oxidative and nitrosative stress in Parkinson's disease

28 July 2018

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Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons

28 July 2018

1 reference

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Replaceable neurons and neurodegenerative disease share depressed UCHL1 levels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron

28 July 2018

1 reference

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Sensitivity of mammalian cells expressing mutant ubiquitin to protein-damaging agents

28 July 2018

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Analysis of ubiquitination in vivo using a transgenic mouse model

28 July 2018

1 reference

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Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

28 July 2018

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Restricted diet rescues rat enteric motor neurones from age related cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

Genomic structure of Unp, a murine gene encoding a ubiquitin-specific protease.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases

28 July 2018

1 reference

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The role of glutathione in dopaminergic neuronal survival.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons

28 July 2018

1 reference

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Progressive degeneration of motor nerve terminals in GAD mutant mouse with hereditary sensory axonopathy

28 July 2018

1 reference

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Parkinson's disease: a disorder due to nigral glutathione deficiency?

28 July 2018

1 reference

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Gracile axonal dystrophy (GAD), a new neurological mutant in the mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

MPTP produces a pattern of nigrostriatal degeneration which coincides with the mosaic organization of the caudate nucleus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

UCHL1 (PGP 9.5): neuronal biomarker and ubiquitin system protein

28 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

Effects of ageing on gastrointestinal motor function

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

UCHL1 is a Parkinson's disease susceptibility gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

Immunohistochemical analysis of neuron types in the mouse small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

An enzyme with ubiquitin carboxy-terminal esterase activity from reticulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

Reactive oxygen species, dietary restriction and neurotrophic factors in age-related loss of myenteric neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

Effects of age on mortality and antibiotic efficacy in cecal ligation and puncture

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

Neurodegeneration: a key factor in the ageing gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2014.00129

The enteric nervous system in chagasic and idiopathic megacolon

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063237

Mutation analysis and association studies of the UCHL1 gene in German Parkinson's disease patients

10 December 2018

1 reference

12 December 2020

Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples

1 reference

12 December 2020

Behavioral study on the gracile axonal dystrophy (GAD) mutant mouse

1 reference

12 December 2020

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

12 December 2020

Identifiers

DOI

10.3389/FNAGI.2014.00129

1 reference

29 July 2017

1 reference

29 July 2017

1 reference