(Q33773655)

English

Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Parkinson's disease

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

0 references

Nathalie Gaborit

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Benoit G. Bruneau

7

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17 January 2020

Robert L. Nussbaum

11

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Robert L Nussbaum

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17 January 2020

Michael D. Gershon

10

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Michael D Gershon

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17 January 2020

author name string

Yien-Ming Kuo

1

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17 January 2020

Zhishan Li

2

1 reference

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17 January 2020

Yun Jiao

3

1 reference

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17 January 2020

Amar K Pani

5

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17 January 2020

Bonnie M Orrison

6

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17 January 2020

Benoit I Giasson

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Richard J Smeyne

9

1 reference

Europe PubMed Central

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17 January 2020

publication date

27 January 2010

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17 January 2020

Human Molecular Genetics

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

19

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1633-1650

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Neuroanatomy and pathology of sporadic Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Lesions outside the CNS in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Parkinson's disease and the gut: a well known clinical association in need of an effective cure and explanation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Invited Article: Nervous system pathology in sporadic Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Abnormal colonic motility in mice overexpressing human wild-type alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Characterization of antibodies that selectively detect alpha-synuclein in pathological inclusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Applicability of current staging/categorization of alpha-synuclein pathology and their clinical relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Parkinson's disease: genetic versus toxin-induced rodent models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Animal models of Parkinson's disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Update on the genetics of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

In vivo alpha-synuclein overexpression in rodents: a useful model of Parkinson's disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Bowel movement frequency in late-life and incidental Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Parkinson's disease: premotor clinico-pathological correlations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Critical appraisal of brain pathology staging related to presymptomatic and symptomatic cases of sporadic Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Parkinson's disease: a rethink of rodent models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Stages in the development of Parkinson's disease-related pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Constipation in idiopathic Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Alzheimer's disease and Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

A highly efficient recombineering-based method for generating conditional knockout mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Staging of the intracerebral inclusion body pathology associated with idiopathic Parkinson's disease (preclinical and clinical stages).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Staging of brain pathology related to sporadic Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Frequency of bowel movements and the future risk of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Ambulatory ECG and analysis of heart rate variability in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Constipation in Parkinson's disease: objective assessment and response to psyllium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Alpha-synuclein in Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Gastrointestinal motility problems in patients with Parkinson's disease. Effects of antiparkinsonian treatment and guidelines for management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

How well does stool form reflect colonic transit?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Fluorescence in situ hybridization of interphase nuclei isolated from whole blood of transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

A large kindred with autosomal dominant Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Gastrointestinal dysfunction in Parkinson's disease: frequency and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Bilateral olfactory dysfunction in early stage treated and untreated idiopathic Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850613

4 July 2018

Alpha synuclein is present in Lewy bodies in sporadic Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Exacerbated synucleinopathy in mice expressing A53T SNCA on a Snca null background

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Association between cardiac denervation and parkinsonism caused by alpha-synuclein gene triplication

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Heart rate variability in mice: a theoretical and practical guide.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Familial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease A 3D [(18)F]dopa-PET study.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Enteric dopaminergic neurons: definition, developmental lineage, and effects of extrinsic denervation.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Loss of enteric dopaminergic neurons and associated changes in colon motility in an MPTP mouse model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Glia cell number modulates sensitivity to MPTP in mice

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ038

21 January 2018

Peripheral and central actions of orphanin FQ (nociceptin) on murine colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controversies over the staging of alpha-synuclein pathology in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathological lesions in colonic biopsies during Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastrointestinal dysfunction in Parkinson's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastrointestinal dysfunction in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal variation in anorectal manometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lewy bodies in the visceral autonomic nervous system in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluid loading of the human colon: effects on segmental transit and stool composition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colonic transit time in nonidiopathic Parkinson's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopaminergic defect of enteric nervous system in Parkinson's disease patients with chronic constipation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compounds possessing 5-HT3 receptor antagonistic activity inhibit intestinal propulsion in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20106867

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDQ038

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20106867%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

ResearchGate publication ID

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