(Q36460467)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16639500%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

review article

1 reference

title

Parkinson's disease: a rethink of rodent models (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16639500%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

4

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20 January 2020

author name string

Heather L Melrose

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16639500%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Sarah J Lincoln

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16639500%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Glenn M Tyndall

series ordinal

3

1 reference

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20 January 2020

publication date

26 April 2006

1 reference

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Experimental Brain Research

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16639500%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

173

1 reference

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20 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16639500%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

196-204

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https://scigraph.springernature.com/pub.10.1007/s00221-006-0461-3

20 January 2020

exact match

0 references

cites work

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

1 reference

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Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation

21 January 2018

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Description of Parkinson's disease as a clinical syndrome.

21 January 2018

1 reference

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Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation.

21 January 2018

1 reference

12 December 2020

Developmental pesticide models of the Parkinson disease phenotype

1 reference

12 December 2020

Synuclein expression is decreased in rat substantia nigra following induction of apoptosis by intrastriatal 6-hydroxydopamine.

1 reference

12 December 2020

Escaping Parkinson's disease: a neurologically healthy octogenarian with the LRRK2 G2019S mutation

1 reference

12 December 2020

The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

1 reference

12 December 2020

Efficient recombination-based methods for bacterial artificial chromosome fusion and mutagenesis

1 reference

12 December 2020

Alpha-synuclein and transgenic mouse models

1 reference

12 December 2020

Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

1 reference

12 December 2020

Mice lacking alpha-synuclein are resistant to mitochondrial toxins

1 reference

12 December 2020

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

1 reference

12 December 2020

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

1 reference

12 December 2020

Parkin gene therapy for alpha-synucleinopathy: a rat model of Parkinson's disease

1 reference

12 December 2020

Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity

1 reference

12 December 2020

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

1 reference

12 December 2020

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

1 reference

12 December 2020

Lrrk2 and Lewy body disease

1 reference

12 December 2020

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

12 December 2020

Overexpression of alpha-synuclein in rat substantia nigra results in loss of dopaminergic neurons, phosphorylation of alpha-synuclein and activation of caspase-9: resemblance to pathogenetic changes in Parkinson's disease

1 reference

12 December 2020

Paraquat neurotoxicity is distinct from that of MPTP and rotenone.

1 reference

12 December 2020

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

1 reference

12 December 2020

Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

1 reference

12 December 2020

Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice

1 reference

12 December 2020

Parkin genetics: one model for Parkinson's disease

1 reference

12 December 2020

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

1 reference

12 December 2020

Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1

1 reference

12 December 2020

Proteomic analysis of parkin knockout mice: alterations in energy metabolism, protein handling and synaptic function

1 reference

12 December 2020

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

12 December 2020

beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

1 reference

12 December 2020

Behavioral phenotyping of the MPTP mouse model of Parkinson's disease

1 reference

12 December 2020

Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP.

1 reference

12 December 2020

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

12 December 2020

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

1 reference

12 December 2020

Complex relationship between Parkin mutations and Parkinson disease

1 reference

12 December 2020

Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse

1 reference

12 December 2020

Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes

1 reference

12 December 2020

Lrrk2 pathogenic substitutions in Parkinson's disease

1 reference

12 December 2020

Environment, mitochondria, and Parkinson's disease

1 reference

12 December 2020

Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia

1 reference

12 December 2020

MPTP: insights into parkinsonian neurodegeneration

1 reference

12 December 2020

Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease

1 reference

12 December 2020

Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations

1 reference

12 December 2020

MPTP toxicity: implications for research in Parkinson's disease

1 reference

12 December 2020

Mechanisms of MPTP toxicity and their implications for therapy of Parkinson's disease

1 reference

12 December 2020

Parkin-deficient mice are not a robust model of parkinsonism

1 reference

12 December 2020

Systematic review of incidence studies of Parkinson's disease

1 reference

12 December 2020

Molecular pathophysiology of Parkinson's disease

1 reference

12 December 2020

6-Hydroxydopamine lesioning differentially affects alpha-synuclein mRNA expression in the nucleus accumbens, striatum and substantia nigra of adult rats.

1 reference

12 December 2020

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

1 reference

12 December 2020

Motor dysfunction and gliosis with preserved dopaminergic markers in human alpha-synuclein A30P transgenic mice

1 reference

12 December 2020

It's a double knock-out! The quaking mouse is a spontaneous deletion of parkin and parkin co-regulated gene (PACRG).

1 reference

12 December 2020

Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers

1 reference

12 December 2020

Stages in the development of Parkinson's disease-related pathology

1 reference

12 December 2020

Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease

1 reference

12 December 2020

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

1 reference

12 December 2020

Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.

1 reference

12 December 2020

Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice

1 reference

12 December 2020

Progression of nigrostriatal dysfunction in a parkin kindred: an [18F]dopa PET and clinical study

1 reference

12 December 2020

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

1 reference

12 December 2020

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

1 reference

12 December 2020

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

1 reference

12 December 2020

Loss of locus coeruleus neurons and reduced startle in parkin null mice

1 reference

12 December 2020

alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

1 reference

12 December 2020

Parkin-proven disease: common founders but divergent phenotypes

1 reference

12 December 2020

The neurological mutant quaking(viable) is Parkin deficient.

1 reference

12 December 2020

Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

1 reference

12 December 2020

Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration

1 reference

12 December 2020

Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice

1 reference

12 December 2020

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

1 reference

12 December 2020

Toxin-induced models of Parkinson's disease

1 reference

12 December 2020

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease

1 reference

12 December 2020

Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice

1 reference

12 December 2020

Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice

1 reference

12 December 2020

Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

1 reference

12 December 2020

Neuropathology in mice expressing human alpha-synuclein

1 reference

12 December 2020

Neuropathology and neurodegeneration in rodent brain induced by lentiviral vector-mediated overexpression of alpha-synuclein

1 reference

12 December 2020

Pathophysiology, pleiotrophy and paradigm shifts: genetic lessons from Parkinson's disease

1 reference

12 December 2020

Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

1 reference

12 December 2020

LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain.

1 reference

12 December 2020

Exacerbated synucleinopathy in mice expressing A53T SNCA on a Snca null background

1 reference

12 December 2020

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

1 reference

12 December 2020

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

1 reference

12 December 2020

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

1 reference

12 December 2020

6-Hydroxydopamine lesion of the rat substantia nigra: time course and morphology of cell death

1 reference

12 December 2020

Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein

1 reference

12 December 2020

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

1 reference

12 December 2020

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

1 reference

12 December 2020

Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis

1 reference

12 December 2020

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

1 reference

12 December 2020

Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

1 reference

12 December 2020

Dopaminergic cell loss induced by human A30P alpha-synuclein gene transfer to the rat substantia nigra

1 reference

12 December 2020

Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates

1 reference

12 December 2020

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

1 reference

12 December 2020

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

1 reference

12 December 2020

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

12 December 2020

10.1007/S00221-006-0461-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16639500%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference