(Q34802076)

4 August 2017

1 reference

title

MPTP: insights into parkinsonian neurodegeneration (English)

1 reference

4 August 2017

1 reference

Samuel G Speciale

1

1 reference

4 August 2017

1 September 2002

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Neurotoxicology and Teratology

4 August 2017

1 reference

4 August 2017

24

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4 August 2017

607-620

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4 August 2017

5

1 reference

Melatonin is protective against MPTP-induced striatal and hippocampal lesions.

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Biochemical mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. Could oxidative stress be involved in the brain?

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Participation of manganese-superoxide dismutase in the neuroprotection exerted by copper sulfate against 1-methyl 4-phenylpyridinium neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Prospective study of caffeine consumption and risk of Parkinson's disease in men and women.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The possible relation of glutathione, melanin and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) to Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Ecogenetics of Parkinson's disease: prevalence and environmental aspects in rural areas

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Degradation of alpha-synuclein by proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Neurogenetic correlates of Parkinson's disease: apolipoprotein-E and cytochrome P450 2D6 genetic polymorphism.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Neuroprotective properties of 17beta-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Parkinson's disease is not one disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Inhibition of uptake of 1-methyl-4-phenylpyridinium ion and dopamine in striatal synaptosomes by tobacco smoke components

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Neuroprotection in the MPTP Parkinsonian C57BL/6 mouse model by a compound isolated from tobacco

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Absence of mutations in the coding region of the alpha-synuclein gene in pathologically proven Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Paraquat: a useful tool for the in vivo study of mechanisms of neuronal cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Evidence for neuromelanin involvement in MPTP-induced neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Selectivity of the parkinsonian neurotoxin MPTP: toxic metabolite MPP+ binds to neuromelanin.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

In vivo imaging of monoaminergic nerve terminals in normal and MPTP-lesioned primate brain using positron emission tomography (PET) and [11C]tetrabenazine.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Is Parkinson's disease acquired or inherited?

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Low frequency of alpha-synuclein mutations in familial Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The protective effects of PBN against MPTP toxicity are independent of hydroxyl radical trapping

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The N-methyl-D-aspartate antagonist MK-801 fails to protect dopaminergic neurons from 1-methyl-4-phenylpyridinium toxicity in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Locus ceruleus lesions and eosinophilic inclusions in MPTP-treated monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

N,N'-bis-dibenzyl ethylenediaminediacetic acid (DBED): a site-specific hydroxyl radical scavenger acting as an "oxidative stress activatable" iron chelator in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Tamoxifen abolishes estrogen's neuroprotective effect upon methamphetamine neurotoxicity of the nigrostriatal dopaminergic system

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Free radical scavengers: chemical concepts and clinical relevance.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminum in Parkinson's disease: a LAMMA study

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Antiparkinsonian effect of a new selective adenosine A2A receptor antagonist in MPTP-treated monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Effects of R- and S-apomorphine on MPTP-induced nigro-striatal dopamine neuronal loss

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Increase in bax expression in substantia nigra following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment of mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Differential neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Swiss-Webster mice from different sources.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Smoking and Parkinson's disease: a case-control study in Germany.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Neurotoxicity at the N-methyl-D-aspartate receptor in energy-compromised neurons. An hypothesis for cell death in aging and disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: an X-ray microanalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Neuronal vulnerability in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Enhanced oxidative stress and altered antioxidants in brains of Bcl-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Age-dependent effects of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP).

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Iron-melanin complex in substantia nigra of parkinsonian brains: an x-ray microanalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Melatonin protects nigral dopaminergic neurons from 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The novel anticonvulsant lamotrigine prevents dopamine depletion in C57 black mice in the MPTP animal model of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Suppressive effect of FK-506, a novel immunosuppressant, against MPTP-induced dopamine depletion in the striatum of young C57BL/6 mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Increased susceptibility to sporadic Parkinson's disease by a certain combined alpha-synuclein/apolipoprotein E genotype

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Parkinson's disease in a chemist working with 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The ubiquitin pathway in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Pesticides and parkinsonism: is there an etiological link?

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Nicotine prevents experimental parkinsonism in rodents and induces striatal increase of neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Pathological basis for neurotransmitter changes in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Reduced expression of the G209A alpha-synuclein allele in familial Parkinsonism.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Novel free radical spin traps protect against malonate and MPTP neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

S-Methylthiocitrulline, a neuronal nitric oxide synthase inhibitor, protects against malonate and MPTP neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Preservation of hypothalamic dopaminergic neurons in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Dysfunction of rat forebrain astrocytes in culture alters cytokine and neurotrophic factor release

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Neurotoxicity of levodopa on catecholamine-rich neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Inhibition of ATP synthesis by 1-methyl-4-phenylpyridinium ion (MPP+) in isolated mitochondria from mouse brains.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

SKF-38393, a dopamine receptor agonist, attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Cell death induced by MPTP, a substrate for monoamine oxidase B.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Abnormalities of the electron transport chain in idiopathic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Differential expression of two vesicular monoamine transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Environmental risk factors and Parkinson's disease: a metaanalysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Subcellular compartmentalization of 1-methyl-4-phenylpyridinium with catecholamines in adrenal medullary chromaffin vesicles may explain the lack of toxicity to adrenal chromaffin cells

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Parkinson's disease--a multifactorial neurodegenerative disorder.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Brain dialysis in conscious rats reveals an instantaneous massive release of striatal dopamine in response to MPP+.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Association of coffee and caffeine intake with the risk of Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Evidence for mitochondrial dysfunction in Parkinson's disease--a critical appraisal

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Introduction: Targeted modulation of neuronal apoptosis: a double-edged sword?

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

DATATOP: A decade of neuroprotective inquiry

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

MPTP: a neurotoxin relevant to the pathophysiology of Parkinson's disease. The 1985 George C. Cotzias lecture

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The neurotoxin 1-methyl-4-phenylpyridinium is sequestered within neurons that contain the vesicular monoamine transporter.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Parkinson disease in twins: an etiologic study

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Paralysis agitans of early onset with marked diurnal fluctuation of symptoms

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

The role of iron in Parkinson disease and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-CH3-MPTP) is a more potent dopaminergic neurotoxin than MPTP in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

In brown Norway rats, MPP+ is accumulated in the nigrostriatal dopaminergic terminals but it is not neurotoxic: a model of natural resistance to MPTP toxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0892-0362%2802%2900222-2

7 January 2021

10.1016/S0892-0362(02)00222-2

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12200192