(Q48364081)

11 February 2018

title

Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins. (English)

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11 February 2018

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3

A H Schapira

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11 February 2018

J M Cooper

series ordinal

2

object named as

J M Cooper

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11 February 2018

author name string

T A Seaton

series ordinal

1

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11 February 2018

language of work or name

English

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publication date

1 October 1998

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11 February 2018

number of pages

6

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based on heuristic

inferred from page(s)

published in

Brain Research

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11 February 2018

volume

809

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11 February 2018

issue

1

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11 February 2018

page(s)

12-17

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11 February 2018

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

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Effects of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine and its metabolite 1-methyl-4-phenylpyridine on acetylcholine synthesis in synaptosomes from rat forebrain

7 January 2021

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Comparative studies on the mechanisms of paraquat and 1-methyl-4-phenylpyridine (MPP+) cytotoxicity

7 January 2021

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Apoptosis and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons

7 January 2021

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Comparison of the effects of NGF, activators of protein kinase C, and a calcium ionophore on the expression of Thy-1 and N-CAM in PC12 cell cultures

7 January 2021

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Biosynthesis of salsolinol, a tetrahydroisoquinoline alkaloid, in healthy subjects

7 January 2021

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Cyclosporin A, an immune suppressor, enhanced neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to mice.

7 January 2021

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Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease

7 January 2021

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7 January 2021

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7 January 2021

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Search for neurotoxins structurally related to 1-methyl-4-phenylpyridine (MPP+) in the pathogenesis of Parkinson's disease

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Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease.

7 January 2021

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

7 January 2021

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

7 January 2021

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Cyclosporine induces neuronal apoptosis and selective oligodendrocyte death in cortical cultures.

7 January 2021

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Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)

7 January 2021

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Inhibition of alpha-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

7 January 2021

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Nigral cell loss produced by infusion of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

7 January 2021

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Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain

7 January 2021

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Inhibition of ATP synthesis by 1-methyl-4-phenylpyridinium ion (MPP+) in isolated mitochondria from mouse brains.

7 January 2021

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Histochemical detection of apoptosis in Parkinson's disease.

7 January 2021

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Cyclosporin A, an immunosuppressive drug, induces programmed cell death in rat C6 glioma cells by a mechanism that involves the AP-1 transcription factor.

7 January 2021

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An endogenous substance of the brain, tetrahydroisoquinoline, produces parkinsonism in primates with decreased dopamine, tyrosine hydroxylase and biopterin in the nigrostriatal regions.

7 January 2021

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Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies.

7 January 2021

1 reference

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Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

7 January 2021

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MPTP, MPP+ and mitochondrial function

7 January 2021

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Detection of tetrahydroisoquinoline in parkinsonian brain as an endogenous amine by use of gas chromatography-mass spectrometry

7 January 2021

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Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

7 January 2021

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Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism

7 January 2021

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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and free radicals in vitro

7 January 2021

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Mitochondrial complex I deficiency in Parkinson's disease

7 January 2021

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On the voltage dependence of the mitochondrial permeability transition pore. A critical appraisal.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2898%2900790-2

Cyclosporin A blocks apoptosis by inhibiting the DNA binding activity of the transcription factor Nur77.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2898%2900790-2

Mitochondrial control of nuclear apoptosis.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-8993%2898%2900790-2

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2898%2900790-2

Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons--a possible novel pathogenetic mechanism in Parkinson's disease.

7 January 2021

1 reference

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10.1016/S0006-8993(98)00790-2

7 January 2021

Identifiers

DOI

1 reference

11 February 2018

PubMed ID

9795106

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11 February 2018