(Q35747138)

10 August 2017

title

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model (English)

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10 August 2017

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15

Haass C

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10 August 2017

9

Trojanowski JQ

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10 August 2017

Kahle PJ

1

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10 August 2017

Neumann M

2

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10 August 2017

Ozmen L

3

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10 August 2017

Müller V

4

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10 August 2017

Odoy S

5

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10 August 2017

Okamoto N

6

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10 August 2017

Jacobsen H

7

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10 August 2017

Iwatsubo T

8

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10 August 2017

Takahashi H

10

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10 August 2017

Wakabayashi K

11

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10 August 2017

Bogdanovic N

12

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10 August 2017

Riederer P

13

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10 August 2017

Kretzschmar HA

14

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10 August 2017

language of work or name

English

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publication date

1 December 2001

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The American Journal of Pathology

10 August 2017

published in

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10 August 2017

volume

159

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10 August 2017

issue

6

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10 August 2017

page(s)

2215-2225

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Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

10 August 2017

cites work

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12 July 2018

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

12 July 2018

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A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

12 July 2018

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Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

12 July 2018

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Parkinson's disease-associated alpha-synuclein is more fibrillogenic than beta- and gamma-synuclein and cannot cross-seed its homologs

12 July 2018

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12 July 2018

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Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

12 July 2018

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12 July 2018

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Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid

12 July 2018

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

12 July 2018

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Juvenile-onset generalized neuroaxonal dystrophy (Hallervorden-Spatz disease) with diffuse neurofibrillary and lewy body pathology

12 July 2018

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Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein

12 July 2018

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Widespread occurrence of alpha-synuclein/NACP-immunoreactive neuronal inclusions in juvenile and adult-onset Hallervorden-Spatz disease with Lewy bodies

12 July 2018

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Multiple system atrophy: a sporadic synucleinopathy

12 July 2018

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Widespread alterations of alpha-synuclein in multiple system atrophy

12 July 2018

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Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.

12 July 2018

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alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

12 July 2018

1 reference

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Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro

12 July 2018

1 reference

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Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

12 July 2018

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Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease

12 July 2018

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Immunoelectron-microscopic demonstration of NACP/alpha-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

The cDNA cloning and ontogeny of mouse alpha-synuclein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity

12 July 2018

1 reference

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NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease

12 July 2018

1 reference

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Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

12 July 2018

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Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

12 July 2018

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Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

12 July 2018

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

12 July 2018

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Alpha-synuclein in Lewy bodies

12 July 2018

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

12 July 2018

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Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system

12 July 2018

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12 July 2018

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Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

7 January 2021

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Identification of two distinct synucleins from human brain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Cell and tissue distribution and developmental change of neuron specific 14 kDa protein (phosphoneuroprotein 14)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Differential regulation of a Thy-1 gene in transgenic mice

12 July 2018

1 reference

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The rat brain synucleins; family of proteins transiently associated with neuronal membrane

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Crosslinking of alpha-synuclein by advanced glycation endproducts--an early pathophysiological step in Lewy body formation?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease?

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Lewy body in neurodegeneration with brain iron accumulation type 1 is immunoreactive for alpha-synuclein

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Alpha-synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome) with widespread cortical and brainstem-type Lewy bodies

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850592

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

25 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963072-6

PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963072-6

Neuropathology in mice expressing human alpha-synuclein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963072-6

alpha-Synuclein immunoreactivity in dementia with Lewy bodies: morphological staging and comparison with ubiquitin immunostaining

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963072-6

In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963072-6

Mutation screening in exons 3 and 4 of alpha-synuclein in sporadic Parkinson's and sporadic and familial dementia with Lewy bodies cases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963072-6

alpha-Synuclein membrane interactions and lipid specificity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963072-6

7 January 2021

1 reference

https://pubmed.ncbi.nlm.nih.gov/11733371

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0002-9440(10)63072-6

1 reference

10 August 2017

1 reference

10 August 2017

1 reference