(Q33781660)

29 July 2017

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title

The antihyperglycaemic effect of metformin: therapeutic and cellular mechanisms (English)

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29 July 2017

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Wiernsperger NF

1

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29 July 2017

Bailey CJ

series ordinal

2

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29 July 2017

publication date

1 January 1999

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29 July 2017

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29 July 2017

volume

58 Suppl 1

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29 July 2017

page(s)

31-9; discussion 75-82

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Effects of Metformin on Lactate Uptake and Gluconeogenesis in the Perfused Rat Liver

29 July 2017

cites work

1 reference

12 December 2020

Biguanides may produce hypoglycemic action in isolated rat hepatocytes through their effects on L-alanine transport

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12 December 2020

U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U.K. Prospective Diabetes Study Group

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Mode of action of hypoglycemic agents. IV. Control of the hypoglycemic activity of phenethylbiguanide in rats and guinea-pigs

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Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.

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Inhibition of hepatic gluconeogenesis by metformin. Synergism with insulin.

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12 December 2020

Effect of metformin on insulin-stimulated glucose transport in isolated skeletal muscle obtained from patients with NIDDM.

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12 December 2020

Inhibition of Carbohydrate-Induced Hypertriglyceridemia by Metformin

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12 December 2020

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12 December 2020

Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells

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12 December 2020

Metformin treatment of lean and obese Zucker rats modulates the ability of glucagon and insulin to regulate hepatocyte adenylate cyclase activity

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12 December 2020

Effect of metformin on glucose metabolism in the splanchnic bed

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12 December 2020

Role of glucose-6 phosphatase, glucokinase, and glucose-6 phosphate in liver insulin resistance and its correction by metformin.

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12 December 2020

Effects of biguanides on fatty acid and glucose oxidation in muscle.

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12 December 2020

Regulation by metformin of the hexose transport system in vascular endothelial and smooth muscle cells

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12 December 2020

Demonstration of defective glucose uptake and storage in erythrocytes from non-insulin dependent diabetic patients and effects of metformin.

1 reference

12 December 2020

1 reference

12 December 2020

Metformin potentiates the antigluconeogenic action of insulin

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12 December 2020

Accumulation of metformin by tissues of the normal and diabetic mouse

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12 December 2020

Hypoglycaemic effect of metformin in genetically obese (fa/fa) rats results from an increased utilization of blood glucose by intestine

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12 December 2020

Biguanide effects on insulin signaling

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12 December 2020

Metformin improves peripheral but not hepatic insulin action in obese patients with type II diabetes.

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12 December 2020

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12 December 2020

Metformin increases insulin-stimulated glucose transport in insulin-resistant human skeletal muscle

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12 December 2020

Inhibition of fatty acid oxidation by biguanides: implications for metabolic physiopathology

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12 December 2020

Acute antihyperglycemic mechanisms of metformin in NIDDM. Evidence for suppression of lipid oxidation and hepatic glucose production

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12 December 2020

Metformin decreases gluconeogenesis by enhancing the pyruvate kinase flux in isolated rat hepatocytes.

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12 December 2020

Clinical pharmacokinetics of metformin

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12 December 2020

Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group.

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12 December 2020

Glucose and lipid metabolism in non-insulin-dependent diabetes. Effect of metformin.

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12 December 2020

Metformin blocks downregulation of cell surface GLUT4 caused by chronic insulin treatment of rat adipocytes

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12 December 2020

Studies on the effect of oral hypoglycaemic agents on hepatic glycogenolysis

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12 December 2020

Potentiating effect of metformin on insulin-induced glucose uptake and glycogen metabolism with Xenopus oocytes

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12 December 2020

Changes in insulin receptor tyrosine kinase activity associated with metformin treatment of type 2 diabetes

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12 December 2020

Dietary fats and insulin action

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12 December 2020

Metformin-insulin interactions: from organ to cell

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12 December 2020

The effects of glucose, insulin and metformin on the order parameters of isolated red cell membranes. An electron paramagnetic resonance spectroscopic study

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12 December 2020

Metformin induces an agonist-specific increase in albumin production by primary cultured rat hepatocytes

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12 December 2020

Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects.

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12 December 2020

Insulin and IGF-1 signaling in oocyte maturation.

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12 December 2020

Prevention of dexamethasone-induced insulin resistance by metformin

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12 December 2020

In vivo metformin treatment ameliorates insulin resistance: evidence for potentiation of insulin-induced translocation and increased functional activity of glucose transporters in obese (fa/fa) Zucker rat adipocytes

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12 December 2020

Regulation of glucose transport and expression of GLUT3 transporters in human circulating mononuclear cells: studies in cells from insulin-dependent diabetic and nondiabetic individuals

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Worldwide experience of metformin as an effective glucose-lowering agent: a meta-analysis

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12 December 2020

Effect of metformin treatment on insulin action in diabetic rats: in vivo and in vitro correlations.

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12 December 2020

Dual effect of metformin in cultured rat hepatocytes: potentiation of insulin action and prevention of insulin-induced resistance

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12 December 2020

Effect of metformin on postprandial lipemia in patients with fairly to poorly controlled NIDDM.

1 reference

12 December 2020

Effect of metformin on glucose metabolism in mouse soleus muscle

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12 December 2020

The antidiabetic drug metformin elevates receptor tyrosine kinase activity and inositol 1,4,5-trisphosphate mass in Xenopus oocytes

1 reference

12 December 2020

Inhibitory effects of metformin on insulin and glucagon action in rat hepatocytes involve post-receptor alterations

1 reference

12 December 2020

Effect of chronic metformin treatment of hepatic and muscle glycogen metabolism in KK mice

1 reference

12 December 2020

Treatment of streptozotocin-diabetic rats with metformin restores the ability of insulin to inhibit adenylate cyclase activity and demonstrates that insulin does not exert this action through the inhibitory guanine nucleotide regulatory protein Gi.

1 reference

12 December 2020

Importance of the intestine as a site of metformin-stimulated glucose utilization

1 reference

12 December 2020

Association of Metformin's Effect to Increase Insulin-Stimulated Glucose Transport With Potentiation of Insulin-Induced Translocation of Glucose Transporters From Intracellular Pool to Plasma Membrane in Rat Adipocytes

1 reference

12 December 2020

Glucose transport in human skeletal muscle cells in culture. Stimulation by insulin and metformin

1 reference

12 December 2020

10.2165/00003495-199958001-00009

Identifiers

DOI

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Dimensions Publication ID

1010066320

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