(Q33782512)

29 July 2017

title

Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity (English)

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29 July 2017

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Christopher R Weber

1

1 reference

29 July 2017

David R Raleigh

2

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29 July 2017

Liping Su

3

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29 July 2017

Le Shen

4

1 reference

29 July 2017

Erika A Sullivan

5

1 reference

29 July 2017

Yingmin Wang

6

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29 July 2017

Jerrold R Turner

7

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29 July 2017

language of work or name

English

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publication date

22 February 2010

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Journal of Biological Chemistry

29 July 2017

published in

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29 July 2017

volume

285

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29 July 2017

issue

16

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29 July 2017

page(s)

12037-12046

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2852941/fullTextXML

inferred from PubMed Central ID database lookup

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis

4 July 2018

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4 July 2018

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4 July 2018

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Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution

4 July 2018

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Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane

4 July 2018

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Defects in mucosal immunity leading to ulcerative colitis

4 July 2018

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Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation?

4 July 2018

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4 July 2018

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Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

4 July 2018

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4 July 2018

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Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis.

4 July 2018

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4 July 2018

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Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms

4 July 2018

1 reference

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Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells

4 July 2018

1 reference

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4 July 2018

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4 July 2018

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4 July 2018

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Interleukins 4 and 13 increase intestinal epithelial permeability by a phosphatidylinositol 3-kinase pathway. Lack of evidence for STAT 6 involvement.

4 July 2018

1 reference

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4 July 2018

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Tumor necrosis factor-alpha increases sodium and chloride conductance across the tight junction of CACO-2 BBE, a human intestinal epithelial cell line.

4 July 2018

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4 July 2018

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4 July 2018

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A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064808

Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064808

IL-13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064808

Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064808

Interferon-gamma selectively increases epithelial permeability to large molecules by activating different populations of paracellular pores

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064808

Both the lymphotoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064808

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064808

Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebo-controlled study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064808

Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064808

Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease

21 January 2018

1 reference

12 December 2020

Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor

1 reference

12 December 2020

Is small intestinal permeability really increased in relatives of patients with Crohn's disease?

1 reference

12 December 2020

Intestinal permeability and the prediction of relapse in Crohn's disease

1 reference

12 December 2020

Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

1 reference

12 December 2020

Regulatory sequences of the mouse villin gene that efficiently drive transgenic expression in immature and differentiated epithelial cells of small and large intestines

1 reference

12 December 2020

Intestinal permeability test as a predictor of clinical course in Crohn's disease

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.064808

1 reference

29 July 2017

1 reference

29 July 2017

1 reference