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Aging, DNA methylation and cancer
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Aging, DNA methylation and cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
main subject
DNA methylation
0 references
author name string
Issa JP
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 September 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
published in
Critical Reviews in Oncology Hematology
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
volume
32
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
page(s)
31-43
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
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Telomeres shorten during ageing of human fibroblasts
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Telomere reduction in human colorectal carcinoma and with ageing
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Telomerase activity, cell proliferation, and cancer
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Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia
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Expression genetics in cancer: shifting the focus from DNA to RNA.
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DNA Methylation and Gene Function
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Dna Methylation in Eukaryote
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DNA methylation and gene activity
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DNA methylation in early development
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The essentials of DNA methylation
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Estradiol down regulates the binding activity of an avian vitellogenin gene repressor (MDBP-2) and triggers a gradual demethylation of the mCpG pair of its DNA binding site
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Localization of methylation sites in the human O6-methylguanine-DNA methyltransferase promoter: correlation with gene suppression
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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
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7 January 2021
based on heuristic
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Cytosine methylation and mammalian development
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7 January 2021
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Active chromatin
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7 January 2021
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inferred from DOI database lookup
DNA methylation and chromatin structure
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7 January 2021
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The effects of 5-azacytidine and 5-azadeoxycytidine on chromosome structure and function: implications for methylation-associated cellular processes
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DNA hypomethylation leads to elevated mutation rates
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inferred from DOI database lookup
Transcriptional silencing of human Alu sequences and inhibition of protein binding in the box B regulatory elements by 5'-CG-3' methylation
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Creation of genomic methylation patterns
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CpG islands and genes
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7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of methylation patterns in the mammalian genome
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7 January 2021
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X-chromosome inactivation in mammals
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reference URL
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7 January 2021
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DNA methylation and genomic imprinting
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Crossref
reference URL
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7 January 2021
based on heuristic
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Reactivation of inactive X-linked genes
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7 January 2021
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Gametic imprinting in mammals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
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7 January 2021
based on heuristic
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Role for DNA methylation in genomic imprinting
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of DNA methylation on DNA-binding proteins and gene expression.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How does DNA methylation repress transcription?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of the cDNA encoding human DNA methyltransferase
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7 January 2021
based on heuristic
inferred from DOI database lookup
A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and analysis of a novel human putative DNA methyltransferase
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of reiterated sequences in mammalian DNAs Effects of the tissue type, age, malignancy and hormonal induction
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
The 5-methylcytosine content of DNA from human tumors
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased methylation of the major mouse long interspersed repeated DNA during aging and in myeloma cells
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of DNA methylation by chemical carcinogens in vitro
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methyl group deficiency in hepatocarcinogenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of DNA methylation in the rat
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA hypomethylation in ethionine-induced rat preneoplastic hepatocyte nodules
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic 5-methyldeoxycytidine decreases associated with the induction of squamous differentiation in cultured normal human bronchial epithelial cells.
1 reference
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related methylation changes in DNA may reflect the proliferative potential of organs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypomethylation of ras oncogenes in primary human cancers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypomethylation of DNA from benign and malignant human colon neoplasms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of c-myc gene changes in human lymphoproliferative diseases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes in methylation pattern of albumin and α-fetoprotein genes in developing rat liver and neoplasia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related changes of proliferative response, kinetics of expression of protooncogenes after the mitogenic stimulation and methylation level of the protooncogene in purified human lymphocyte subsets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An embryonic-like methylation pattern of classical satellite DNA is observed in ICF syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA demethylation and pericentromeric rearrangements of chromosome 1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation and genetic instability in colorectal cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic instability in colorectal cancers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of intestinal neoplasia by DNA hypomethylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of 5-azacytidine in syrian golden hamsters: Toxicity, tumorigenicity, and differential modulation of bronchial carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased cytosine DNA-methyltransferase activity during colon cancer progression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular distribution of DNA methyltransferase during the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation and silencing of the Thrombospondin-1 promoter in human cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inheritance of epigenetic defects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation in aging and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation decreases in aging but not in immortal cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Strong effects of 5-azacytidine on the in vitro lifespan of human diploid fibroblasts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro senescence of human keratinocyte cultures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Maintenance of DNA methylation level in SV40-infected human fibroblasts during their in vitro limited proliferative life span
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation and epigenetic mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation in aging of mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of repetitive DNA sequences in the brain during aging of the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-related increase in methylation of ribosomal genes and inactivation of chromosome-specific rRNA gene clusters in mouse.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Changes of the methylation pattern of the c-myc gene during in vitro aging of IMR90 human embryonic fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of the c-myc gene changes during aging process of mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Messenger RNA levels and methylation patterns of GAPDH and beta-actin genes in rat liver, spleen and brain in relation to aging.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous virus genomes become hypomethylated tissue--specifically during aging process of C57BL mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of CpG-island-containing genes in human sperm, fetal and adult tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age-associated changes in DNA methylation and mRNA level of the c-myc gene in spleen and liver of mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of age-associated changes of c-myc gene methylation in liver between man and mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Concordant methylation of the ER and N33 genes in glioblastoma multiforme.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of ageing on reactivation of the human X-linked HPRT locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stability of DNA methylation of X-chromosome genes during aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypermethylation of chromosome 17P locus D17S5 in human prostate tissue.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epigenetic gene inactivation induced by a cis-acting methylation center.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sp1 elements protect a CpG island from de novo methylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hormone replacement therapy, reproductive history, and colon cancer: a multicenter, case-control study in the United States
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of gene expression in plants as a consequence of specific sequence duplication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of crossing-over by DNA methylation in Ascobolus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1040-8428%2899%2900019-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1040-8428(99)00019-0
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
PubMed ID
10586353
1 reference
stated in
Europe PubMed Central
PubMed ID
10586353
retrieved
29 July 2017
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