(Q33787533)

29 July 2017

title

Calcium sensitivity, force frequency relationship and cardiac troponin I: critical role of PKA and PKC phosphorylation sites (English)

1 reference

29 July 2017

1 reference

Genaro A Ramirez-Correa

1

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29 July 2017

Sonia Cortassa

2

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29 July 2017

Brian Stanley

3

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29 July 2017

Wei Dong Gao

4

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29 July 2017

Anne M Murphy

5

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29 July 2017

language of work or name

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18 January 2010

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Journal of Molecular and Cellular Cardiology

29 July 2017

published in

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29 July 2017

volume

48

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29 July 2017

issue

5

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29 July 2017

page(s)

943-953

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Distinct sarcomeric substrates are responsible for protein kinase D-mediated regulation of cardiac myofilament Ca2+ sensitivity and cross-bridge cycling

29 July 2017

cites work

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4 July 2018

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Acceleration of crossbridge kinetics by protein kinase A phosphorylation of cardiac myosin binding protein C modulates cardiac function.

4 July 2018

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Negative charges at protein kinase C sites of troponin I stabilize the inactive state of actin

4 July 2018

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A computational model integrating electrophysiology, contraction, and mitochondrial bioenergetics in the ventricular myocyte

4 July 2018

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Regulation of cardiac contractile function by troponin I phosphorylation

4 July 2018

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Calcium, thin filaments, and the integrative biology of cardiac contractility

4 July 2018

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In vivo and in vitro analysis of cardiac troponin I phosphorylation

4 July 2018

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Force-frequency relationship in intact mammalian ventricular myocardium: physiological and pathophysiological relevance

4 July 2018

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PKC-alpha regulates cardiac contractility and propensity toward heart failure

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Covalent and noncovalent modification of thin filament action: the essential role of troponin in cardiac muscle regulation.

4 July 2018

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Inhibition of PKC phosphorylation of cTnI improves cardiac performance in vivo

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Targeting phospholamban by gene transfer in human heart failure

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Regulation of contraction in striated muscle

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Phospholamban: a major determinant of the cardiac force-frequency relationship

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

In vivo phosphorylation of cardiac troponin I by protein kinase Cbeta2 decreases cardiomyocyte calcium responsiveness and contractility in transgenic mouse hearts

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

The relationship between contractile force and intracellular [Ca2+] in intact rat cardiac trabeculae

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Cardiac troponin I mutants. Phosphorylation by protein kinases C and A and regulation of Ca(2+)-stimulated MgATPase of reconstituted actomyosin S-1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Intracellular calcium transients underlying the short-term force-interval relationship in ferret ventricular myocardium

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Calcium transients in aequorin-injected frog cardiac muscle

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Cardiac transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Frequency-dependent myofilament Ca2+ desensitization in failing rat myocardium

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Roles of phosphorylation of myosin binding protein-C and troponin I in mouse cardiac muscle twitch dynamics.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Frequency- and afterload-dependent cardiac modulation in vivo by troponin I with constitutively active protein kinase A phosphorylation sites.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Altered force-frequency response in non-failing hearts with decreased SERCA pump-level

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Protein kinase C and A sites on troponin I regulate myofilament Ca2+ sensitivity and ATPase activity in the mouse myocardium

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Phosphorylation of troponin I controls cardiac twitch dynamics: evidence from phosphorylation site mutants expressed on a troponin I-null background in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Levosimendan improves diastolic and systolic function in failing human myocardium.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Troponin I protein kinase C phosphorylation sites and ventricular function

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854165

Calcium cycling and contractile activation in intact mouse cardiac muscle

30 October 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Frequency-dependent changes in calcium cycling and contractile activation in SERCA2a transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Intrinsic myofilament alterations underlying the decreased contractility of stunned myocardium. A consequence of Ca2+-dependent proteolysis?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Myofilament Ca2+ sensitivity in intact versus skinned rat ventricular muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Effect of inotropic stimulation on the negative force-frequency relationship in the failing human heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Differential roles of cardiac myosin-binding protein C and cardiac troponin I in the myofibrillar force responses to protein kinase A phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Beta-adrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Cardiac troponin I phosphorylation increases the rate of cardiac muscle relaxation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Nitroxyl increases force development in rat cardiac muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

PKC-betaII sensitizes cardiac myofilaments to Ca2+ by phosphorylating troponin I on threonine-144

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

A kinetic model for the binding of Ca2+ to the regulatory site of troponin from cardiac muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Power output is increased after phosphorylation of myofibrillar proteins in rat skinned cardiac myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.01.004

Positive force- and [Ca2+]i-frequency relationships in rat ventricular trabeculae at physiological frequencies

7 January 2021

1 reference

12 December 2020

Comparison of putative cooperative mechanisms in cardiac muscle: length dependence and dynamic responses

1 reference

12 December 2020

Measurement of myofilament calcium sensitivity at physiological temperature in intact cardiac trabeculae

1 reference

12 December 2020

Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function

1 reference

12 December 2020

Frequency-dependent acceleration of relaxation involves decreased myofilament calcium sensitivity

1 reference

12 December 2020

10.1016/J.YJMCC.2010.01.004

Identifiers

DOI

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29 July 2017

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29 July 2017

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