(Q33792264)

29 July 2017

title

A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics (English)

1 reference

29 July 2017

0 references

1 reference

Brett M Babin

2

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author name string

Colin L Walsh

1

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29 July 2017

Rachel W Kasinskas

3

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29 July 2017

Jean A Foster

4

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29 July 2017

Marissa J McGarry

5

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29 July 2017

Neil S Forbes

6

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29 July 2017

publication date

21 November 2008

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29 July 2017

number of pages

10

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inferred from page(s)

published in

Lab on a Chip

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29 July 2017

volume

9

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29 July 2017

issue

4

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29 July 2017

page(s)

545-554

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2855303/fullTextXML

inferred from PubMed Central ID database lookup

cites work

pH-responsive nanoparticles for cancer drug delivery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Microfluidic self-assembly of tumor spheroids for anticancer drug discovery

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Drug resistance and the solid tumor microenvironment

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Molecular description of a 3D in vitro model for the study of epithelial ovarian cancer (EOC).

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

pH-sensitive liposomes--principle and application in cancer therapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Salmonella typhimurium lacking ribose chemoreceptors localize in tumor quiescence and induce apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Flux analysis shows that hypoxia-inducible-factor-1-alpha minimally affects intracellular metabolism in tumor spheroids

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

The use of targeted mouse models for preclinical testing of novel cancer therapeutics.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

A biocompatible micro cell culture chamber (microCCC) for the culturing and on-line monitoring of eukaryote cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Drug penetration in solid tumours

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Transparent polymeric cell culture chip with integrated temperature control and uniform media perfusion

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Salmonella typhimurium specifically chemotax and proliferate in heterogeneous tumor tissue in vitro

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Glutathione-mediated delivery and release using monolayer protected nanoparticle carriers

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Repopulation of cancer cells during therapy: an important cause of treatment failure

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

50 years of preclinical anticancer drug screening: empirical to target-driven approaches.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

NanoLiterBioReactor: long-term mammalian cell culture at nanofabricated scale

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Effects of medium perfusion rate on cell-seeded three-dimensional bone constructs in vitro

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Poly(dimethylsiloxane) as a material for fabricating microfluidic devices

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Tumor physiology and drug resistance

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Transport of molecules, particles, and cells in solid tumors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Tumor biology and experimental therapeutics

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Paclitaxel-induced apoptosis in non-small cell lung cancer cell lines is associated with increased caspase-3 activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

The next frontier of molecular medicine: delivery of therapeutics.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Growth and cellular characteristics of multicell spheroids.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Cell and environment interactions in tumor microregions: the multicell spheroid model

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Quick and accurate method to convert BCECF fluorescence to pHi: Calibration in three different types of cell preparations

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Two-dimensional diffusion limited system for cell growth.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Profile of a bacterial tumor killer.

28 July 2018

1 reference

Incorporating energy metabolism into a growth model of multicellular tumor spheroids.

21 January 2018

1 reference

Quantification of longitudinal tissue pO2 gradients in window chamber tumours: impact on tumour hypoxia

21 January 2018

1 reference

Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response

21 January 2018

1 reference

A novel high aspect ratio microfluidic design to provide a stable and uniform microenvironment for cell growth in a high throughput mammalian cell culture array

21 January 2018

1 reference

Gelatin based microfluidic devices for cell culture.

21 January 2018

1 reference

A parametric study of human fibroblasts culture in a microchannel bioreactor.

21 January 2018

1 reference

A novel 3D mammalian cell perfusion-culture system in microfluidic channels.

21 January 2018

1 reference

Three-dimensional perfusion culture of human bone marrow cells and generation of osteoinductive grafts.

21 January 2018

1 reference

Development and characterization of a small-scale bioreactor based on a bioartificial hepatic culture model for predictive pharmacological in vitro screenings.

21 January 2018

1 reference

Perfusion of medium improves growth of human oral neomucosal tissue constructs

21 January 2018

1 reference

The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo.

21 January 2018

1 reference

A mathematical model of drug transport in human breast cancer.

21 January 2018

1 reference

Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Effect of longitudinal oxygen gradients on effectiveness of manipulation of tumor oxygenation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Limited penetration of anticancer drugs through tumor tissue: a potential cause of resistance of solid tumors to chemotherapy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855303

Influence of flow conditions and matrix coatings on growth and differentiation of three-dimensionally cultured rat hepatocytes

30 October 2018

1 reference

12 December 2020

Selective dissociation and characterization of cells from different regions of multicell tumor spheroids

1 reference

12 December 2020

Regulation of growth saturation and development of necrosis in EMT6/Ro multicellular spheroids by the glucose and oxygen supply

1 reference

12 December 2020

Fluorescence ratio imaging measurement of pH gradients: calibration and application in normal and tumor tissues

1 reference

12 December 2020

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

1 reference

12 December 2020

Light-regulated release of DNA and its delivery to nuclei by means of photolabile gold nanoparticles

1 reference

12 December 2020

Identifiers

DOI

10.1039/B810571E

1 reference

29 July 2017

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29 July 2017

1 reference