(Q33794797)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling (English)

1 reference

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21 March 2020

3

1 reference

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21 March 2020

author name string

Jian-Guo Ren

1

1 reference

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21 March 2020

Pankaj Seth

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Pawel K Lorkiewicz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Richard M Higashi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Andrew N Lane

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Teresa W-M Fan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Vikas P Sukhatme

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

language of work or name

English

0 references

publication date

24 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

page(s)

5414

1 reference

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

21 March 2020

copyright license

start time

24 June 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

New targetable oncogenes in non-small-cell lung cancer

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Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence

28 July 2018

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High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS.

28 July 2018

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Comprehensive genomic characterization of squamous cell lung cancers

28 July 2018

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Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

28 July 2018

1 reference

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Mitochondrial Akt-regulated mitochondrial apoptosis signaling in cardiac muscle cells

28 July 2018

1 reference

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Reactive oxygen species production by forward and reverse electron fluxes in the mitochondrial respiratory chain

28 July 2018

1 reference

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Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2

28 July 2018

1 reference

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Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions

28 July 2018

1 reference

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Redox-optimized ROS balance: a unifying hypothesis

28 July 2018

1 reference

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Akt1 intramitochondrial cycling is a crucial step in the redox modulation of cell cycle progression

28 July 2018

1 reference

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Isotopomer analysis of lipid biosynthesis by high resolution mass spectrometry and NMR.

28 July 2018

1 reference

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Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067620

Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067620

The basal flux of Akt in the mitochondria is mediated by heat shock protein 90.

28 July 2018

1 reference

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Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067620

Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067620

Pyruvate kinase M2 is a phosphotyrosine-binding protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067620

A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067620

Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067620

K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.

28 July 2018

1 reference

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Gleevec (STI-571) inhibits lung cancer cell growth (A549) and potentiates the cisplatin effect in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067620

The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme

28 July 2018

1 reference

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In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors

28 July 2018

1 reference

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Glutaminase activities and growth rates of rat hepatomas.

28 July 2018

1 reference

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Cytoskeletal changes as an early event in hydrogen peroxide-induced cell injury: a study in A549 cells

28 July 2018

1 reference

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Deviant energetic metabolism of glycolytic cancer cells

28 July 2018

1 reference

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Malic enzyme and malate dehydrogenase activities in rat tracheal epithelial cells during the progression of neoplasia.

28 July 2018

1 reference

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Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways

21 January 2018

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Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes.

21 January 2018

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Hydrogen peroxide controls Akt activity via ubiquitination/degradation pathways.

21 January 2018

1 reference

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Reactive oxygen species induced by diamide inhibit insulin-induced ATP-sensitive potassium channel activation in cultured vascular smooth muscle cells.

30 October 2018

1 reference

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Expression of p14ARF overcomes tumor resistance to p53.

30 October 2018

1 reference

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Involvement of Fenton reaction products in differentiation induction of K562 human leukemia cells

30 October 2018

1 reference

12 December 2020

Mitochondrial malic enzymes. Mitochondrial NAD(P)+-dependent malic enzyme activity and malate-dependent pyruvate formation are progression-linked in Morris hepatomas

1 reference

12 December 2020

Metformin inhibits inflammatory response via AMPK-PTEN pathway in vascular smooth muscle cells

1 reference

12 December 2020

Trends in incidence of small cell lung cancer and all lung cancer

1 reference

12 December 2020

Apoptosis, redifferentiation and arresting proliferation simultaneously triggered by oxidative stress in human hepatoma cells

1 reference

12 December 2020

Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP05414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

24957098

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957098%20AND%20SRC:MED&resulttype=core&format=json