(Q28504783)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

GOA release 2020-03-11

author

Anne Le

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Sminu Bose

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Daniel C. Liebler

12

1 reference

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19 January 2020

Chi V. Dang

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

13

Robbert J C Slebos

1 reference

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19 January 2020

9

Barbara S Slusher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Max Hamaker

3

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Arvin Gouw

5

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Joseph Barbi

6

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Takashi Tsukamoto

7

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Haixia Zhang

10

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Andrew N Lane

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Camilio J Rojas

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Lisa J Zimmerman

11

1 reference

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19 January 2020

Pawel K Lorkiewicz

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Richard M Higashi

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Teresa W M Fan

16

1 reference

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19 January 2020

publication date

1 January 2012

1 reference

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19 January 2020

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

15

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

110-121

1 reference

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19 January 2020

issue

1

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

Full-length human glutaminase in complex with an allosteric inhibitor

19 January 2020

cites work

1 reference

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

19 March 2017

1 reference

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

19 March 2017

1 reference

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Brick by brick: metabolism and tumor cell growth

19 March 2017

1 reference

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Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

19 March 2017

1 reference

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

19 March 2017

1 reference

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Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth

19 March 2017

1 reference

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

19 March 2017

1 reference

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19 March 2017

2 references

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19 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

29 September 2017

1 reference

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

7 April 2017

1 reference

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Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

7 April 2017

1 reference

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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

7 April 2017

1 reference

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Otto Warburg's contributions to current concepts of cancer metabolism

7 April 2017

1 reference

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Reductive carboxylation supports growth in tumour cells with defective mitochondria.

29 September 2017

1 reference

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Targeting cancer metabolism: a therapeutic window opens

29 September 2017

1 reference

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Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

29 September 2017

1 reference

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Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

29 September 2017

1 reference

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Normalization of the vasculature for treatment of cancer and other diseases

29 September 2017

1 reference

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Stable isotope resolved metabolomics of lung cancer in a SCID mouse model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

IDH mutations in glioma and acute myeloid leukemia

29 September 2017

1 reference

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Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Rethinking the Warburg effect with Myc micromanaging glutamine metabolism

29 September 2017

1 reference

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MYC-induced cancer cell energy metabolism and therapeutic opportunities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Mitochondrial uncoupling and the Warburg effect: molecular basis for the reprogramming of cancer cell metabolism

29 September 2017

1 reference

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Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo

29 September 2017

1 reference

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The oncoprotein H-RasV12 increases mitochondrial metabolism

29 September 2017

1 reference

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Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Control of cell growth by c-Myc in the absence of cell division

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

Hypoxia divergently regulates production of reactive oxygen species in human pulmonary and coronary artery smooth muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3345194

10.1016/J.CMET.2011.12.009

27 November 2018

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22225880%20AND%20SRC:MED&resulttype=core&format=json