(Q34554818)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

review article

1 reference

title

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

3

1 reference

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28 December 2019

author name string

King A

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Selak MA

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

language of work or name

English

0 references

publication date

1 August 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

page(s)

4675-4682

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

issue

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209594

28 December 2019

exact match

0 references

cites work

Mitochondrial defects in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

On the association of succinate dehydrogenase mutations with hereditary paraganglioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

An Alu-mediated partial SDHC deletion causes familial and sporadic paraganglioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Mitochondrial succinate is instrumental for HIF1alpha nuclear translocation in SDHA-mutant fibroblasts under normoxic conditions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Evolving concepts in pheochromocytoma and paraganglioma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Oncogenic alterations of metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Dioxygenases as O2-dependent regulators of the hypoxic response pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

SDHD mutations in head and neck paragangliomas result in destabilization of complex II in the mitochondrial respiratory chain with loss of enzymatic activity and abnormal mitochondrial morphology.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

A role for mitochondrial enzymes in inherited neoplasia and beyond

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Hereditary paraganglioma/pheochromocytoma and inherited succinate dehydrogenase deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Why do cancers have high aerobic glycolysis?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

JunD reduces tumor angiogenesis by protecting cells from oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Functional consequences of a SDHB gene mutation in an apparently sporadic pheochromocytoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Mitochondrial tumour suppressors: a genetic and biochemical update

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Pharmacological manipulation of cell death: clinical applications in sight?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Beginnings of a signal-transduction pathway for bioenergetic control of cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

The HIF pathway as a therapeutic target

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Dysregulation of the TSC-mTOR pathway in human disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Role of VHL gene mutation in human cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

The HIF pathway in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Hypoxia-inducible factor as a physiological regulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Mitochondrial dysfunction in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

The key role of anaplerosis and cataplerosis for citric acid cycle function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Mutations of the SDHB and SDHD genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis

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7 January 2021

Akt-dependent transformation: there is more to growth than just surviving

1 reference

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7 January 2021

Evidence of increased microvessel density and activation of the hypoxia pathway in tumours from the hereditary leiomyomatosis and renal cell cancer syndrome.

1 reference

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7 January 2021

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

1 reference

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7 January 2021

Mitochondria, oxygen free radicals, disease and ageing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Mitochondrial hexokinases: guardians of the mitochondria

1 reference

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7 January 2021

Inborn errors of complex II--unusual human mitochondrial diseases

1 reference

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7 January 2021

Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Oxygen sensing by HIF hydroxylases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Signalling hypoxia by HIF hydroxylases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Distinct expression profile in fumarate-hydratase-deficient uterine fibroids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Novel mutations in FH and expansion of the spectrum of phenotypes expressed in families with hereditary leiomyomatosis and renal cell cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Glycobiology and cancer: meeting summary and future diections

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Architecture of succinate dehydrogenase and reactive oxygen species generation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Cancer metabolism: facts, fantasy, and fiction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209594

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209594

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16892081%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 December 2019

0 references

1 reference