(Q33799197)

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Effective caspase inhibition blocks neutrophil apoptosis and reveals Mcl-1 as both a regulator and a target of neutrophil caspase activation

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Effective caspase inhibition blocks neutrophil apoptosis and reveals Mcl-1 as both a regulator and a target of neutrophil caspase activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Colin D. Bingle

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Stephen A. Renshaw

object named as

Stephen A Renshaw

6

0 references

object named as

Ian Sabroe

3

0 references

Moira K B Whyte

5

object named as

Moira K B Whyte

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

David J Wardle

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Joseph Burgon

2

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Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

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publication date

6 January 2011

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

e15768

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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Creative Commons Attribution 4.0 International

6 January 2011

1 reference

April 2022 Public Data File from Crossref

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0 references

15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Constitutive neutrophil apoptosis: mechanisms and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Deactivation of phosphatidylinositol 3,4,5-trisphosphate/Akt signaling mediates neutrophil spontaneous death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Resolution of inflammation: the beginning programs the end

1 reference

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4 July 2018

Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance

1 reference

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4 July 2018

Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

The role of interleukin-1beta in direct and toll-like receptor 4-mediated neutrophil activation and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Cleavage of Mcl-1 by caspases impaired its ability to counteract Bim-induced apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Regulation of neutrophil apoptosis by Mcl-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

What can we learn from highly purified neutrophils?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Characterisation of Mcl-1 cleavage during apoptosis of haematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Activation of adherent vascular neutrophils in the lung during acute endotoxemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

4 July 2018

The cyclin-dependent kinase inhibitor R-roscovitine down-regulates Mcl-1 to override pro-inflammatory signalling and drive neutrophil apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Cyclic AMP delays neutrophil apoptosis via stabilization of Mcl-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Sodium salicylate promotes neutrophil apoptosis by stimulating caspase-dependent turnover of Mcl-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Characterization of the survival effect of tumour necrosis factor-alpha in human neutrophils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Granulocyte macrophage colony-stimulating factor signaling and proteasome inhibition delay neutrophil apoptosis by increasing the stability of Mcl-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Spontaneous in contrast to CD95-induced neutrophil apoptosis is independent of caspase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3017075

30 October 2018

Resolution of acute inflammation and the role of apoptosis in the tissue fate of granulocytes

1 reference

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30 October 2018

Inflammatory neutrophils retain susceptibility to apoptosis mediated via the Fas death receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21253591

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The loss of Mcl-1 expression in human polymorphonuclear leukocytes promotes apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21253591

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of PMN apoptosis by hypoxia is dependent on Mcl-1 and MAPK activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21253591

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/21253591

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mcl-1 expression in human neutrophils: regulation by cytokines and correlation with cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/21253591

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive apoptosis in human neutrophils requires synergy between calpains and the proteasome downstream of caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21253591

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and Bax, Bcl-2, Mcl-1 expression in neutrophils of Crohn's disease patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21253591

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0015768

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

2011PLoSO...615768W

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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