(Q33799901)

29 July 2017

title

Exogenous Nef is an inhibitor of Mycobacterium tuberculosis-induced tumor necrosis factor-alpha production and macrophage apoptosis (English)

1 reference

Mycobacterium tuberculosis

29 July 2017

main subject

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author name string

Kuldeep Kumawat

1

1 reference

29 July 2017

Sushil Kumar Pathak

2

1 reference

29 July 2017

Anna-Lena Spetz

3

1 reference

29 July 2017

Manikuntala Kundu

4

1 reference

29 July 2017

Joyoti Basu

5

1 reference

29 July 2017

language of work or name

English

0 references

publication date

12 January 2010

1 reference

Journal of Biological Chemistry

29 July 2017

published in

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29 July 2017

volume

285

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29 July 2017

issue

17

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29 July 2017

page(s)

12629-12637

1 reference

HIV-1 Nef interferes with host cell motility by deregulation of Cofilin

29 July 2017

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4 July 2018

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4 July 2018

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4 July 2018

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Mycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophages

4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages

4 July 2018

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4 July 2018

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Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.

4 July 2018

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4 July 2018

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Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300.

4 July 2018

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Exogenous Nef protein activates NF-kappa B, AP-1, and c-Jun N-terminal kinase and stimulates HIV transcription in promonocytic cells. Role in AIDS pathogenesis

4 July 2018

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4 July 2018

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4 July 2018

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HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

4 July 2018

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HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

4 July 2018

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Mechanism for down-regulation of CD28 by Nef.

4 July 2018

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Regulation of tumour necrosis factor alpha mRNA stability by the mitogen-activated protein kinase p38 signalling cascade

4 July 2018

1 reference

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Lipoarabinomannan from Mycobacterium tuberculosis promotes macrophage survival by phosphorylating Bad through a phosphatidylinositol 3-kinase/Akt pathway

4 July 2018

1 reference

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4 July 2018

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4 July 2018

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The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells

4 July 2018

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4 July 2018

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Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner

4 July 2018

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4 July 2018

1 reference

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Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

4 July 2018

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Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF alpha promoter in stimulated mast cells

4 July 2018

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Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

4 July 2018

1 reference

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Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes.

4 July 2018

1 reference

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Relative contribution of transcription and translation to the induction of tumor necrosis factor-alpha by lipopolysaccharide

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Effects of mycobacteria on regulation of apoptosis in mononuclear phagocytes.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Cytomegalovirus modulates transcription factors necessary for the activation of the tumor necrosis factor-alpha promoter.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Infection by Mycobacterium tuberculosis promotes human alveolar macrophage apoptosis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Cell-type-specific regulation of the human tumor necrosis factor alpha gene in B cells and T cells by NFATp and ATF-2/JUN.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+ T cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

4 July 2018

1 reference

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HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Interaction of nuclear proteins with an AP-1/CRE-like promoter sequence in the human TNF-alpha gene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

C/EBP beta regulation of the tumor necrosis factor alpha gene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857058

The Nef protein of human immunodeficiency virus establishes superinfection immunity by a dual strategy to downregulate cell-surface CCR5 and CD4.

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.073320

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.073320

Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.073320

HIV impairs TNF-alpha mediated macrophage apoptotic response to Mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.073320

HIV-1 Nef induces the release of inflammatory factors from human monocyte/macrophages: involvement of Nef endocytotic signals and NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.073320

In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of mitogen-activated protein kinases, IkappaB kinases, and interferon regulatory factor 3 and to the r

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.073320

HIV-1 Nef protects human-monocyte-derived macrophages from HIV-1-induced apoptosis

21 January 2018

1 reference

12 December 2020

p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation

1 reference

12 December 2020

Massive Secretion by T Cells Is Caused by HIV Nef in Infected Cells and by Nef Transfer to Bystander Cells

1 reference

12 December 2020

Macrophages and T-cell apoptosis in HIV infection: a leading role for accessory cells?

1 reference

12 December 2020

HIV-1 Nef activates STAT1 in human monocytes/macrophages through the release of soluble factors

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.073320

1 reference

29 July 2017

1 reference

29 July 2017

1 reference