(Q33800456)

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Vorinostat interferes with the signaling transduction pathway of T-cell receptor and synergizes with phosphoinositide-3 kinase inhibitors in cutaneous T-cell lymphoma.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133897%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Vorinostat interferes with the signaling transduction pathway of T-cell receptor and synergizes with phosphoinositide-3 kinase inhibitors in cutaneous T-cell lymphoma (English)

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17 January 2020

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17 January 2020

Daniel Martín-Pérez

9

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17 January 2020

Miguel A. Piris

12

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17 January 2020

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Magdalena B Wozniak

1

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17 January 2020

Raquel Villuendas

2

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17 January 2020

James R Bischoff

3

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17 January 2020

Carmen Blanco Aparicio

4

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17 January 2020

Paloma de La Cueva

6

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17 January 2020

Ma Elena Rodriguez

7

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17 January 2020

Beatriz Herreros

8

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17 January 2020

Maria I Longo

10

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17 January 2020

Marta Herrera

11

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17 January 2020

Pablo L Ortiz-Romero

13

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17 January 2020

publication date

4 February 2010

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17 January 2020

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17 January 2020

95

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17 January 2020

4

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17 January 2020

613-621

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17 January 2020

Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3-kinases

1 reference

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4 July 2018

Co-treatment with heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG) and vorinostat: a highly active combination against human mantle cell lymphoma (MCL) cells

1 reference

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4 July 2018

Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma

1 reference

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Critical roles of the PI3K/Akt signaling pathway in T cell development

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Histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis through both mitochondrial and Fas (Cd95) signaling in head and neck squamous carcinoma cells.

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Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

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4 July 2018

Selective induction of apoptosis by histone deacetylase inhibitor SAHA in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action

1 reference

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Targeting histones and proteasomes: new strategies for the treatment of lymphoma

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The spectrum of cutaneous T-cell lymphomas: new insights into biology and therapy

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Histone deacetylase inhibitors in programmed cell death and cancer therapy

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Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

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The pathogenesis of mycosis fungoides

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Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1

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Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications

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Histone deacetylase inhibitors in cancer therapy: is transcription the primary target?

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4 July 2018

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

1 reference

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4 July 2018

Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration

1 reference

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Histone deacetylases and cancer: causes and therapies

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4 July 2018

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

1 reference

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Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

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4 July 2018

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1 reference

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Signal transduction by lymphocyte antigen receptors

1 reference

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1 reference

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Identifiers

10.3324/HAEMATOL.2009.013870

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133897%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PMC publication ID

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Europe PubMed Central

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17 January 2020

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Europe PubMed Central

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17 January 2020

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