(Q33813191)

29 July 2017

1 reference

title

Profile and mechanisms of gastrointestinal and other side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). (English)

1 reference

29 July 2017

K D Rainsford

1

1 reference

PubMed ID

10628591

29 July 2017

language of work or name

English

0 references

publication date

1 December 1999

1 reference

American Journal of Medicine

29 July 2017

1 reference

29 July 2017

107

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29 July 2017

6A

1 reference

29 July 2017

27S-35S; discussion 35S-36S

1 reference

Effect of non-steroidal anti-inflammatory drugs on the course of osteoarthritis

29 July 2017

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The treatment of osteoarthritis

7 January 2021

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Cyclo-oxygenase isoenzymes. How recent findings affect thinking about nonsteroidal anti-inflammatory drugs

7 January 2021

1 reference

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Review article: COX-II inhibitors--a new generation of safer NSAIDs?

7 January 2021

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7 January 2021

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Nimesulide. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy

7 January 2021

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An analysis from clinico-epidemiological data of the principal adverse events from the COX-2 selective NSAID, nimesulide, with particular reference to hepatic injury

7 January 2021

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Risk of hospitalization for upper gastrointestinal tract bleeding associated with ketorolac, other nonsteroidal anti-inflammatory drugs, calcium antagonists, and other antihypertensive drugs

7 January 2021

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Ketorolac use in outpatients and gastrointestinal hospitalization: a comparison with other non-steroidal anti-inflammatory drugs in Italy.

7 January 2021

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Association of upper gastrointestinal toxicity of non-steroidal anti-inflammatory drugs with continued exposure: cohort study

7 January 2021

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Protection from gastrointestinal side-effects by azapropazone by its incorporation into a glucose-sodium acid citrate formulation

7 January 2021

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Relationship of gastric mucosal damage induced in pigs by antiinflammatory drugs to their effects on prostaglandin production

7 January 2021

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Classical absorption theory and the development of gastric mucosal damage associated with the non-steroidal anti-inflammatory drugs

7 January 2021

1 reference

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Dissolution and partition thermodynamic functions of some nonsteroidal anti-inflammatory drugs.

7 January 2021

1 reference

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The amphiprotic character of azapropazone and its relevance to the gastric mucosa

7 January 2021

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hP, the component of log P controlling structure-activity relationships amongst non-steroidal anti-inflammatory drugs

7 January 2021

1 reference

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Interactions of Nonsteroidal Antiinflammatory Drugs with Phospholipids: Comparison between Octanol/Buffer Partition Coefficients and Chromatographic Indexes on Immobilized Artificial Membranes

7 January 2021

1 reference

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Structure-activity relationships of non-steroid anti-inflammatory drug 1. Gastric ulcerogenic activity

7 January 2021

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Esterification of acidic anti-inflammatory drugs suppresses their gastrotoxicity without adversely affecting their anti-inflammatory activity in rats

7 January 2021

1 reference

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Gastric ulcerogenicity of non-steroidal anti-inflammatory drugs in mice with mucosa sensitized by cholinomimetic treatment

7 January 2021

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Correlation between gastric irritancy and anti-inflammatory activity of non-steroidal anti-inflammatory drugs

7 January 2021

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Preclinical overview of nabumetone. Pharmacology, bioavailability, metabolism, and toxicology

7 January 2021

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Antiinflammatory and gastrointestinal effects of nabumetone or its active metabolite, 6-methoxy-2-naphthylacetic acid (6MNA). Comparative studies with indomethacin

7 January 2021

1 reference

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Relationship between lipophilicity and binding to human serum albumin of arylpropionic acid non-steroidal anti-inflammatory drugs

7 January 2021

1 reference

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Role of surface-active phospholipids in gastric cytoprotection

7 January 2021

1 reference

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Phosphatidylcholines as mediators of adaptive cytoprotection of the rat duodenum.

7 January 2021

1 reference

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Gastric mucosal barrier: barrier to hydrogen ions imparted by gastric surfactant in vitro

7 January 2021

1 reference

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Non-steroidal anti-inflammatory drugs (NSAIDs) associate with zwitterionic phospholipids: Insight into the mechanism and reversal of NSAID-induced gastrointestinal injury

7 January 2021

1 reference

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Deranged hydrophobic barrier of the rat gastroduodenal mucosa after parenteral nonsteroidal anti-inflammatory drugs

7 January 2021

1 reference

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Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): rationale for selective inhibition and progress to date

7 January 2021

1 reference

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Biochemical pharmacology of nonsteroidal anti-inflammatory drugs

7 January 2021

1 reference

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Differentiating among nonsteroidal antiinflammatory drugs by pharmacokinetic and pharmacodynamic profiles

7 January 2021

1 reference

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

7 January 2021

1 reference

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Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2

7 January 2021

1 reference

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Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents

7 January 2021

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A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

7 January 2021

1 reference

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Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.

7 January 2021

1 reference

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Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor

7 January 2021

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Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2

7 January 2021

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Differential allosteric regulation of prostaglandin H synthase 1 and 2 by arachidonic acid

7 January 2021

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The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs

7 January 2021

1 reference

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7 January 2021

Cyclooxygenases 1 and 2

1 reference

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Effects of the prodrug nabumetone, and its active metabolite, 6-MNA, on human and rat gastric mucosal prostanoids and platelet function

7 January 2021

1 reference

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Comparative effects of nabumetone, sulindac, and indomethacin on urinary prostaglandin excretion and platelet function in volunteers

7 January 2021

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Nabumetone. A reappraisal of its pharmacology and therapeutic use in rheumatic diseases

7 January 2021

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Gastrointestinal irritancy, antiinflammatory activity, and prostanoid inhibition in the rat. Differentiation of effects between nabumetone and etodolac

7 January 2021

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Importance of local versus systemic effects of non-steroidal anti-inflammatory drugs in increasing small intestinal permeability in man

7 January 2021

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Effects of meloxicam, compared with other NSAIDs, on cartilage proteoglycan metabolism, synovial prostaglandin E2, and production of interleukins 1, 6 and 8, in human and porcine explants in organ culture.

7 January 2021

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Can non-steroidal anti-inflammatory drugs act as metalloproteinase modulators? An in-vitro study of inhibition of collagenase activity

7 January 2021

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Luminal surface hydrophobicity of canine gastric mucosa is dependent on a surface mucous gel.

7 January 2021

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Morphological effects of aspirin and prostaglandin on the canine gastric mucosal surface. Analysis with a phospholipid-selective cytochemical stain

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0002-9343(99)00365-4

1 reference

29 July 2017

1 reference

PubMed ID

10628591